Lian Deng, Xiaoran Wu, Xiongjie Zhu, Zhongjian Yu, Zhile Liu, Jinting Wang, Yanfang Zheng: Combination effect of curcumin with docetaxel on the PI3K/AKT/mTOR pathway to induce autophagy and apoptosis in esophageal squamous cell carcinoma. American Journal of Translational Research 2021;13(1):57-72. (Full text, PDF)
Min Xiao, Chunhua Lin, Zhaoxin Yang, Shuhong Tian, Yanan Huang, Jian Fu: Compound TDB (Tricyclic decyl benzoxazole) induces autophagy-dependent apoptosis in the gastric cancer cell line MGC-803 by regulating PI3K/AKT/mTOR. American Journal of Translational Research 2021;13(1):73-87. (Full text, PDF)
Zhuolong Tu, Xiaoqi Jiang, Yuan Li, Shiwei Yang, Deyong Lin, Yingfeng Shi, Cong Mao, Xingxing Zhang, Cai Lin: Curcumin promotes the survival of ischemic random skin flaps via autophagy. American Journal of Translational Research 2021;13(3):1337-1351. (Full text, PDF)
Yi-Ren Qin, Chi-Qian Ma, Da-Peng Wang, Quan-Quan Zhang, Mei-Rong Liu, Hong-Ru Zhao, Jian-Hua Jiang, Qi Fang: Bilobalide alleviates neuroinflammation and promotes autophagy in Alzheimer’s disease by upregulating lincRNA-p21. American Journal of Translational Research 2021;13(4):2021-2040. (Full text, PDF)
Bin Zhang, Yan Zhang, Rongzhen Li, Jiazhen Li, Xinchang Lu, Yi Zhang: Oncolytic adenovirus Ad11 enhances the chemotherapy effect of cisplatin on osteosarcoma cells by inhibiting autophagy. American Journal of Translational Research 2020;12(1):105-117. (Full text, PDF)
Youdan Dong, Zeming Zhang, Hezuo Liu, Lihong Jia, Muting Qin, Xiaofei Wang: Exacerbating lupus nephritis following BPA exposure is associated with abnormal autophagy in MRL/lpr mice. American Journal of Translational Research 2020;12(2):649-659. (Full text, PDF)
Rui Zhang, Xiao-Quan Huang, Ying-Yi Jiang, Na Li, Jian Wang, Shi-Yao Chen: LncRNA TUG1 regulates autophagy-mediated endothelial-mesenchymal transition of liver sinusoidal endothelial cells by sponging miR-142-3p. American Journal of Translational Research 2020;12(3):758-772. (Full text, PDF)
Xiao-Jie Zhang, Dong-Mei Liu, Ying Sun, Yan-Shan Li, Li-Li Ma, Xiu-Fang Kong, Xiao-Meng Cui, Rong-Yi Chen, Zhuo-Jun Zhang, Lin-Di Jiang: Potential risk of hyperuricemia: leading cardiomyocyte hypertrophy by inducing autophagy. American Journal of Translational Research 2020;12(5):1894-1903. (Full text, PDF)
Feng Zhang, Qianwen Li, Kai Zhu, Junfeng Zhu, Jiajia Li, Yuan Yuan, Pingping Zhang, Lili Zhou, Lin Liu: LncRNA LINC00265/miR-485-5p/IRF2-mediated autophagy suppresses apoptosis in acute myeloid leukemia cells. American Journal of Translational Research 2020;12(6):2451-2462. (Full text, PDF)
Jing Zheng, Min Zeng, Jia-Bin Nian, Lian-Ya Zeng, Zhi Fu, Qiu-Ju Huang, Xin Wei: The CXCR4/miR-125b/FoxP3 axis regulates the function of the epithelial barrier via autophagy in allergic rhinitis. American Journal of Translational Research 2020;12(6):2570-2584. (Full text, PDF)
Xinghan Liu, Yujun Xu, Yi Li, Yuchen Pan, Zhiheng Sun, Shuli Zhao, Yayi Hou: Ganoderma lucidum fruiting body extracts inhibit colorectal cancer by inducing apoptosis, autophagy, and G0/G1 phase cell cycle arrest in vitro and in vivo. American Journal of Translational Research 2020;12(6):2675-2684. (Full text, PDF)
Gang Chen, Jiandong Li, Zhenyu Wang, Wenge Liu: Ezetimibe protects against spinal cord injury by regulating autophagy and apoptosis through inactivation of PI3K/AKT/mTOR signaling. American Journal of Translational Research 2020;12(6):2685-2694. (Full text, PDF)
Banglv Ju, Zhilan Liu, Chao Nai, Xinyong Zhu: Long non-coding RNA CASC2 induces apoptosis and autophagy in human colon cancer cells via modulation of TRIM16 expression. American Journal of Translational Research 2020;12(6):2695-2702. (Full text, PDF)
Xueqin Li, Lei Gao, Linjing Zheng, Jing Shi, Junli Ma: BMP4-mediated autophagy is involved in the metastasis of hepatocellular carcinoma via JNK/Beclin1 signaling. American Journal of Translational Research 2020;12(6):3068-3077. (Full text, PDF)
Jinwu Wang, Jie Cai, Xingyu Wang, Gaosheng Zhu, Yongzeng Feng, Hua Chen, Leyi Cai: An injectable liposome for sustained release of tanshinone IIA to the treatment of acute blunt muscle injury by augmenting autophagy and alleviating oxidative stress. American Journal of Translational Research 2020;12(8):4189-4203. (Full text, PDF)
Fan Zhou, Jingjing Jin, Lin Zhou, Longyun Wu, Yu Cao, Hongli Yan, Qin Huang, Lei Wang, Xiaoping Zou: Suppression of estrogen receptor-beta promotes gastric cancer cell apoptosis with induction of autophagy. American Journal of Translational Research 2020;12(8):4397-4409. (Full text, PDF)
Xuejing Guan, Jie Shen, Yahong Xu, Xuefang Feng, Rong Zhou: Heme oxygenase-1 enhances autophagy by modulating the AMPK/mTORC1 signaling pathway as a renoprotective mechanism to mitigate lead-induced nephrotoxicity. American Journal of Translational Research 2020;12(8):4807-4818. (Full text, PDF)
Xun Chen, Xiao-Ru Yan, Jing Liu, Li-Ping Zhang: Chaiqi decoction ameliorates vascular endothelial injury in metabolic syndrome by upregulating autophagy. American Journal of Translational Research 2020;12(9):4902-4922. (Full text, PDF)
Chongxin He, Jie Xia, Yinghua Gao, Zhilong Chen, Xinjian Wan: Chlorin A-mediated photodynamic therapy induced apoptosis in human cholangiocarcinoma cells via impaired autophagy flux. American Journal of Translational Research 2020;12(9):5080-5094. (Full text, PDF)
Bo Sheng, Yizuo Song, Jianan Zhang, Ruyi Li, Zhiwei Wang, Xueqiong Zhu: Atorvastatin suppresses the progression of cervical cancer via regulation of autophagy. American Journal of Translational Research 2020;12(9):5252-5268. (Full text, PDF)
Shanqiang Qu, Shuhao Liu, Weiwen Qiu, Jin Liu, Huafu Wang: Screening of autophagy genes as prognostic indicators for glioma patients. American Journal of Translational Research 2020;12(9):5320-5331. (Full text, PDF)
Tong Zhang, Hongxin Wang, Meili Lu, Kun Zhao, Jiawei Yin, Yang Liu, Yang Sun: Astragaloside IV prevents myocardial hypertrophy induced by mechanical stress by activating autophagy and reducing inflammation. American Journal of Translational Research 2020;12(9):5332-5342. (Full text, PDF)
Fenglin Hu, Xufeng Tao, Liang Zhao, Fangyue Guo, Qi Zhou, Huiyi Song, Hong Xiang, Dong Shang: LncRNA-PVT1 aggravates severe acute pancreatitis by promoting autophagy via the miR-30a-5p/Beclin-1 axis. American Journal of Translational Research 2020;12(9):5551-5562. (Full text, PDF)
Yong Li, Xuguan Chen, Peng Li, Qianxuan Xiao, Daorong Hou, Xiangqing Kong: CD47 antibody suppresses isoproterenol-induced cardiac hypertrophy through activation of autophagy. American Journal of Translational Research 2020;12(9):5908-5923. (Full text, PDF)
Weicheng Xu, Xu Zhao, Panpan Sun, Cong Zhang, Zhijian Fu, Dongsheng Zhou: The effect of medical ozone treatment on cartilage chondrocyte autophagy in a rat model of osteoarthritis. American Journal of Translational Research 2020;12(9):5967-5976. (Full text, PDF)
Retraction: Oncolytic adenovirus Ad11 enhances the chemotherapy effect of cisplatin on osteosarcoma cells by inhibiting autophagy. American Journal of Translational Research 2020;12(9):5992. (Full text, PDF)
Hui Zuo, Cheng Chen, Ling Ma, Qiu-Xia Min, Yue-Hai Shen: Caspase-8 knockdown suppresses apoptosis, while induces autophagy and chemo-sensitivity in non-small cell lung cancer cells. American Journal of Translational Research 2020;12(10):6478-6489. (Full text, PDF)
Wanli Yang, Liaoran Niu, Xinhui Zhao, Lili Duan, Yiding Li, Xiaoqian Wang, Yujie Zhang, Wei Zhou, Jinqiang Liu, Qingchuan Zhao, Yu Han, Daiming Fan, Liu Hong: Development and validation of a survival model based on autophagy-associated genes for predicting prognosis of hepatocellular carcinoma. American Journal of Translational Research 2020;12(10):6705-6722. (Full text, PDF)
Shuyu Fang, Chaoqun Hu, Lei Xu, Jiejie Cui, Li Tao, Mengjia Gong, Yi Wang, Yun He, Tongchuan He, Yang Bi: All-trans-retinoic acid inhibits the malignant behaviors of hepatocarcinoma cells by regulating autophagy. American Journal of Translational Research 2020;12(10):6793-6810. (Full text, PDF)
Jing Zheng, Min Zeng, Jia-Bin Nian, Lian-Ya Zeng, Zhi Fu, Qiu-Ju Huang, Xin Wei: The CXCR4/miR-125b/FoxP3 axis regulates the function of the epithelial barrier via autophagy in allergic rhinitis. American Journal of Translational Research 2020;12(10):6975. (Full text, PDF)
Peng Chu, Shisheng Wang, Xinxing Zhu, Ying Yang, Hailong Li, Tsehaye Tesfaldet, Abdullah Shopit, Yongliang Yang, Xiaodong Ma, Jinyong Peng, Zeyao Tang, Zhaolin Sun: Selaginellin B induces apoptosis and autophagy in pancreatic cancer cells via the JAK2/STAT3 signaling pathway. American Journal of Translational Research 2020;12(11):7127-7143. (Full text, PDF, Supplementary Movie)
Yanghua Tang, Yafeng Mo, Dawei Xin, Linru Zeng, Zhenshuang Yue, Canda Xu: β-ecdysterone alleviates osteoarthritis by activating autophagy in chondrocytes through regulating PI3K/AKT/mTOR signal pathway. American Journal of Translational Research 2020;12(11):7174-7186. (Full text, PDF)
Lingfeng Meng, Zijian Tian, Xingbo Long, Tongxiang Diao, Maolin Hu, Miao Wang, Wei Zhang, Yaoguang Zhang, Jianye Wang, Yuhui He: Prognostic autophagy model based on CASP4 and BIRC5 expression in patients with renal cancer: independent datasets-based study. American Journal of Translational Research 2020;12(11):7475-7489. (Full text, PDF)
Jun Zheng, Jin Tan, Yu-Yang Miao, Qiang Zhang: Extracellular vesicles degradation pathway based autophagy lysosome pathway. American Journal of Translational Research 2019;11(3):1170-1183. (Full text, PDF)
Juan Wen, Jiajie Wang, Lan Guo, Weijun Cai, Yang Wu, Wei Chen, Xiaohong Tang: Chemerin stimulates aortic smooth muscle cell proliferation and migration via activation of autophagy in VSMCs of metabolic hypertension rats. American Journal of Translational Research 2019;11(3):1327-1342. (Full text, PDF)
Jing Ding, Fangchun Jin, Xiang Zhao, Li Zhao, Zhenkai Wu, Jiyu Li: Hemiepiphysiodesis stapling induces ER stress apoptosis and autophagy in rat growth plates. American Journal of Translational Research 2019;11(3):1486-1497. (Full text, PDF)
Yanping Zhang, Yan Geng, Juntao He, Dong Wu, Tong Zhang, Li Xue, Lei Zhang, Aili He: Tanshinone IIA induces apoptosis and autophagy in acute monocytic leukemia via downregulation of PI3K/Akt pathway. American Journal of Translational Research 2019;11(5):2995-3006. (Full text, PDF)
Weiting Cheng, Wei Xiang, Shan Wang, Kai Xu: Tanshinone IIA ameliorates oxaliplatin-induced neurotoxicity via mitochondrial protection and autophagy promotion. American Journal of Translational Research 2019;11(5):3140-3149. (Full text, PDF)
Min Wang, Shenglong Qiu, Jun Qin: Baicalein induced apoptosis and autophagy of undifferentiated thyroid cancer cells by the ERK/PI3K/Akt pathway. American Journal of Translational Research 2019;11(6):3341-3352. (Full text, PDF)
Langen Zhuang, Guoxi Jin, Xiaolei Hu, Qingqing Yang, Zhaoming Shi: The inhibition of SGK1 suppresses epithelial-mesenchymal transition and promotes renal tubular epithelial cell autophagy in diabetic nephropathy. American Journal of Translational Research 2019;11(8):4946-4956. (Full text, PDF)
Xin-Qiu-Yue Wang, Zong-Tang Xu, Gui-Ping Zhang, Ning Hou, Qin-Xing Mo, Jie Wei, Xin Jiang, Yun Liu, Jian-Dong Luo: Endophilin A2 attenuates cardiac hypertrophy induced by isoproterenol through the activation of autophagy. American Journal of Translational Research 2019;11(8):5065-5075. (Full text, PDF)
Qi Wang, Zhile Liu, Kunpeng Du, Min Liang, Xiongjie Zhu, Zhongjian Yu, Rui Chen, Lingyu Qin, Ying Li, Yanfang Zheng: Babaodan inhibits cell growth by inducing autophagy through the PI3K/AKT/mTOR pathway and enhances antitumor effects of cisplatin in NSCLC cells. American Journal of Translational Research 2019;11(8):5272-5283. (Full text, PDF)
Haiquan Huang, Haifeng Ni, Kunling Ma, Jihong Zou: ANGPTL2 regulates autophagy through the MEK/ERK/Nrf-1 pathway and affects the progression of renal fibrosis in diabetic nephropathy. American Journal of Translational Research 2019;11(9):5472-5486. (Full text, PDF)
Guoxin Tong, Yongmei Wang, Chenke Xu, Yizhou Xu, Xianhua Ye, Liang Zhou, Gangjie Zhu, Zhanlin Zhou, Jinyu Huang: Long non-coding RNA FOXD3-AS1 aggravates ischemia/reperfusion injury of cardiomyocytes through promoting autophagy. American Journal of Translational Research 2019;11(9):5634-5644. (Full text, PDF)
Keren Wu, Jie Huang, Tao Xu, Zhipeng Ye, Fa Jin, Ning Li, Bin Lv: MicroRNA-181b blocks gensenoside Rg3-mediated tumor suppression of gallbladder carcinoma by promoting autophagy flux via CREBRF/CREB3 pathway. American Journal of Translational Research 2019;11(9):5776-5787. (Full text, PDF)
Zengxin Gao, Yucheng Lin, Pei Zhang, Qinghua Cheng, Linhui Ye, Fuhua Wu, Yingjun Chen, Minghui Fu, Changgui Cheng, Yucheng Gao: Sinomenine ameliorates intervertebral disc degeneration via inhibition of apoptosis and autophagy in vitro and in vivo. American Journal of Translational Research 2019;11(9):5956-5966. (Full text, PDF)
Hyun-Jin Jang, Kyeong Eun Yang, In-Hu Hwang, Yang Hoon Huh, Dae Joon Kim, Hwa-Seung Yoo, Soo Jung Park, Ik-Soon Jang: Cordycepin inhibits human ovarian cancer by inducing autophagy and apoptosis through Dickkopf-related protein 1/β-catenin signaling. American Journal of Translational Research 2019;11(11):6890-6906. (Full text, PDF)
Weiping Liu, Shaoling Li, Ziling Qu, Yi Luo, Ruifeng Chen, Sufen Wei, Xin Yang, Qi Wang: Betulinic acid induces autophagy-mediated apoptosis through suppression of the PI3K/AKT/mTOR signaling pathway and inhibits hepatocellular carcinoma. American Journal of Translational Research 2019;11(11):6952-6964. (Full text, PDF)
Rong Zeng, Xiao-Jun Song, Chang-Wei Liu, Wei Ye: LncRNA ANRIL promotes angiogenesis and thrombosis by modulating microRNA-99a and microRNA-449a in the autophagy pathway. American Journal of Translational Research 2019;11(12):7441-7448. (Full text, PDF)
Haoyuan Jia, Wanzhu Liu, Bin Zhang, Juanjuan Wang, Peipei Wu, Nitin Tandra, Zhaofeng Liang, Cheng Ji, Lei Yin, Xinyuan Hu, Yongmin Yan, Fei Mao, Xu Zhang, Jing Yu, Wenrong Xu, Hui Qian: HucMSC exosomes-delivered 14-3-3ζ enhanced autophagy via modulation of ATG16L in preventing cisplatin-induced acute kidney injury. American Journal of Translational Research 2018;10(1):101-113. (Full text, PDF)
Jingjing Dai, Yong Liang, Honglin Li, Wubi Zhou, Bing Wang, Aijia Gong, Rongbo Zhang: Vitamin D enhances resistance to aspergillus fumigatus in mice via inhibition of excessive autophagy. American Journal of Translational Research 2018;10(2):381-391. (Full text, PDF)
Beiyun Wang, Jing Huang, Jingbo Li, Yuan Zhong: Control of macrophage autophagy by miR-384-5p in the development of diabetic encephalopathy. American Journal of Translational Research 2018;10(2):511-518. (Full text, PDF)
Qingbin Zhang, Shixiang Lai, Xunyao Hou, Wei Cao, Ying Zhang, Zhaoqiang Zhang: Protective effects of PI3K/Akt signal pathway induced cell autophagy in rat knee joint cartilage injury. American Journal of Translational Research 2018;10(3):762-770. (Full text, PDF)
Long Li, Hongyan Yin, Yan Zhao, Xiaofang Zhang, Chaoli Duan, Jing Liu, Caoxin Huang, Suhuan Liu, Shuyu Yang, Xuejun Li: Protective role of puerarin on LPS/D-Gal induced acute liver injury via restoring autophagy. American Journal of Translational Research 2018;10(3):957-965. (Full text, PDF)
Wenxia Xu, Qiqi Shi, Xiaoling Qian, Bingluo Zhou, Jinye Xu, Liyuan Zhu, Lifeng Feng, Hongchuan Jin, Xian Wang: Rab5a suppresses autophagy to promote drug resistance in cancer cells. American Journal of Translational Research 2018;10(4):1229-1236. (Full text, PDF)
Yuelong Ma, Qin Pei, Li Zhang, Jie Lu, Tiejun Shui, Jia Chen, Chao Shi, Jun Yang, Michael Smith, Yeqiang Liu, Jianyu Zhu, Degang Yang: Live Mycobacterium leprae inhibits autophagy and apoptosis of infected macrophages and prevents engulfment of host cell by phagocytes. American Journal of Translational Research 2018;10(9):2929-2939. (Full text, PDF)
Shaoming Zhu, Wei Li, Xiao Yang, Weimin Yu, Ting Rao, Yuan Ruan, Jinzhuo Ning, Run Yuan, Haoyong Li, Kun Jiang, Chenglong Li, Fan Cheng: Effects of autophagy on the spermatogonia of chronic hypoxic mice. American Journal of Translational Research 2018;10(12):4119-4129. (Full text, PDF)
Yexun Song, Wei Li, Xiaowei Peng, Jun Xie, Heqing Li, Guolin Tan: Inhibition of autophagy results in a reversal of taxol resistance in nasopharyngeal carcinoma by enhancing taxol-induced caspase-dependent apoptosis. American Journal of Translational Research 2017;9(4):1934-1942. (Full text, PDF)
Shu Li, Jin-Wei Chen, Xi Xie, Jing Tian, Cong Deng, Jia Wang, Hai-Na Gan, Fen Li: Autophagy inhibitor regulates apoptosis and proliferation of synovial fibroblasts through the inhibition of PI3K/AKT pathway in collagen-induced arthritis rat model. American Journal of Translational Research 2017;9(5):2065-2076. (Full text, PDF)
Bingke Lv, Tian Hua, Feng Li, Jianbang Han, Jie Fang, Limin Xu, Chengmei Sun, Zhongfei Zhang, Zhiming Feng, Xiaodan Jiang: Hypoxia-inducible factor 1 α protects mesenchymal stem cells against oxygen-glucose deprivation-induced injury via autophagy induction and PI3K/AKT/mTOR signaling pathway. American Journal of Translational Research 2017;9(5):2492-2499. (Full text, PDF)
Yong-Da Liu, Zhi-Bin Wang, Guang Han, Ping Zhao: Hyperbaric oxygen treatment attenuates neuropathic pain by elevating autophagy flux via inhibiting mTOR pathway. American Journal of Translational Research 2017;9(5):2629-2638. (Full text, PDF)
Shaohua Dai, Qirong Xu, Sheng Liu, Bentong Yu, Jichun Liu, Jian Tang: Role of autophagy and its signaling pathways in ischemia/reperfusion injury. American Journal of Translational Research 2017;9(10):4470-4480. (Full text, PDF)
Jinquan Hu, Hui Han, Peng Cao, Wenchao Yu, Chen Yang, Yang Gao, Wen Yuan: Resveratrol improves neuron protection and functional recovery through enhancement of autophagy after spinal cord injury in mice. American Journal of Translational Research 2017;9(10):4607-4616. (Full text, PDF)
Xin-Yu Wang, Xue-Hong Zhang, Li Peng, Zheng Liu, Yin-Xue Yang, Zhi-Xu He, Hong-Wan Dang, Shu-Feng Zhou: Bardoxolone methyl (CDDO-Me or RTA402) induces cell cycle arrest, apoptosis and autophagy via PI3K/Akt/mTOR and p38 MAPK/Erk1/2 signaling pathways in K562 cells. American Journal of Translational Research 2017;9(10):4652-4672. (Full text, PDF)
Qing-Hua Cao, Fang Liu, Zu-Li Yang, Xin-Hui Fu, Zi-Huan Yang, Quentin Liu, Lei Wang, Xiang-Bo Wan, Xin-Juan Fan: Prognostic value of autophagy related proteins ULK1, Beclin 1, ATG3, ATG5, ATG7, ATG9, ATG10, ATG12, LC3B and p62/SQSTM1 in gastric cancer. American Journal of Translational Research 2016;8(9):3831-3847. (Full text, PDF)
Qunjun Duan, Weijun Yang, Daming Jiang, Kaiyu Tao, Aiqiang Dong, Haifeng Cheng: Spermine ameliorates ischemia/reperfusion injury in cardiomyocytes via regulation of autophagy. American Journal of Translational Research 2016;8(9):3976-3985. (Full text, PDF)
Shyam Sundar Nandi, Michael J Duryee, Hamid R Shahshahan, Geoffrey M Thiele, Daniel R Anderson, Paras K Mishra: Induction of autophagy markers is associated with attenuation of miR-133a in diabetic heart failure patients undergoing mechanical unloading. American Journal of Translational Research 2015;7(4):683-696. (Full text, PDF)
Jia Chen, Qi Wang, Fu-Qiang Yin, Wei Zhang, Lin-Hai Yan, Li Li: MTRR silencing inhibits growth and cisplatin resistance of ovarian carcinoma via inducing apoptosis and reducing autophagy. American Journal of Translational Research 2015;7(9):1510-1527. (Full text, PDF)
Yanchun Chen, Huancai Liu, Yingjun Guan, Qiaozhen Wang, Fenghua Zhou, Linlin Jie, Jie Ju, Leidong Pu, Hongmei Du, Xin Wang: The altered autophagy mediated by TFEB in animal and cell models of amyotrophic lateral sclerosis. American Journal of Translational Research 2015;7(9):1574-1587. (Full text, PDF)
Jinghui Yang, Qi Chen, Shiyin Tian, Shaohua Song, Fang Liu, Quanxing Wang, Zhiren Fu: The role of 1,25-dyhydroxyvitamin D3 in mouse liver ischemia reperfusion injury: regulation of autophagy through activation of MEK/ERK signaling and PTEN/PI3K/Akt/mTORC1 signaling. American Journal of Translational Research 2015;7(12):2630-2645. (Full text, PDF)
Mei Sun, Li Tan, Min Hu: The role of autophagy in hepatic fibrosis. American Journal of Translational Research 2021;13(6):5747-5757. (Full text, PDF)
Weidong Zhou, Qingsong Yu, Junjie Ma, Chengdang Xu, Denglong Wu, Chao Li: Triamcinolone acetonide combined with 5-fluorouracil suppresses urethral scar fibroblasts autophagy and fibrosis by increasing miR-192-5p expression. American Journal of Translational Research 2021;13(6):5956-5968. (Full text, PDF)
Elgin Turkoz Uluer, Pinar Kilicaslan Sonmez, Damla Akogullari, Melike Onal, Gamze Tanriover, Sevinc Inan: Do Wortmannin and Thalidomide induce apoptosis by autophagy inhibition in 4T1 breast cancer cells in vitro and in vivo?. American Journal of Translational Research 2021;13(6):6236-6247. (Full text, PDF)
Jinwu Wang, Jie Cai, Xingyu Wang, Gaosheng Zhu, Yongzeng Feng, Hua Chen, Leyi Cai: An injectable liposome for sustained release of tanshinone IIA to the treatment of acute blunt muscle injury by augmenting autophagy and alleviating oxidative stress. American Journal of Translational Research 2021;13(6):7422-7424. (Full text, PDF)
Hui Shen, Yan Sha, Jun Huang, An-Qi Mao, Tao Zhang, Mu-Yao Wu, Fang Sun, Ying-Yuan Yu, Zhong-Qin Cheng, Ya-Ting Gong: The roles of AMPK-mediated autophagy and mitochondrial autophagy in a mouse model of imiquimod-induced psoriasis. American Journal of Translational Research 2021;13(11):12626-12637. (Full text, PDF)
Yanshang Wang, Ling Ding, Xian Wang, Jingyi Zhang, Weidong Han, Lifeng Feng, Jie Sun, Hongchuan Jin, Xiao Jia Wang: Pterostilbene simultaneously induces apoptosis, cell cycle arrest and cyto-protective autophagy in breast cancer cells. American Journal of Translational Research 2012;4(1):44-51. (Full text, PDF)
Jianjie Qin, Junjin Zhou, Xinzheng Dai, Haoming Zhou, Xiongxiong Pan, Xuehao Wang, Feng Zhang, Jianhua Rao, Ling Lu: Short-term starvation attenuates liver ischemia-reperfusion injury (IRI) by Sirt1-autophagy signaling in mice. American Journal of Translational Research 2016;8(8):3364-3375. (Full text, PDF)
Sheng Liu, Jun Zhang, Bentong Yu, Lei Huang, Bin Dai, Jichun Liu, Jian Tang: The role of autophagy in lung ischemia/reperfusion injury after lung transplantation in rats. American Journal of Translational Research 2016;8(8):3593-3602. (Full text, PDF)
Qian-Juan Fang, Bing-Huan Chi, Qi-Cheng Lin, Chen-Miao Huang, Shao-Wu Jin, Jia-Jing Cai, Ke Nan, Yuan Han, Yuan-Xiang Tao, Hong Cao, Jun Li: Surgery-induced downregulation of hippocampal sirtuin-1 contributes to cognitive dysfunction by inhibiting autophagy and activating apoptosis in aged mice. American Journal of Translational Research 2020;12(12):8111-8122. (Full text, PDF)
Tian Li, Shiyi Zhang, Fengsong Chen, Jun Hu, Shuai Yuan, Chaoran Li, Xiaoting Wang, Weihong Zhang, Runwei Tang: Formononetin ameliorates the drug resistance of Taxol resistant triple negative breast cancer by inhibiting autophagy. American Journal of Translational Research 2021;13(2):497-514. (Full text, PDF)
Zhen Zhang, Dongming Zhu, Xiaobo Zhang, Yun Liu, Jingcheng Wang, Lianqi Yan: Tanshinone IIA regulates fibroblast proliferation and migration and post-surgery arthrofibrosis through the autophagy-mediated PI3K and AMPK-mTOR signaling pathway. American Journal of Translational Research 2021;13(2):565-584. (Full text, PDF)
Fang Yang, Zhiqiang Yan, Wei Nie, Xingzhen Cheng, Zeying Liu, Wei Wang, Chunyan Shao, Gui Fu, Yanni Yu: LACTB induced apoptosis of oxaliplatin-resistant gastric cancer through regulating autophagy-mediated mitochondrial apoptosis pathway. American Journal of Translational Research 2021;13(2):601-616. (Full text, PDF)
Yulong Luo, Lin Fan, Lixing Huang, Canhui Ouyang, Qiuping Zhu: Expression of serum autophagy-related protein P62 in patients with severe pancreatitis and its correlation with prognosis. American Journal of Translational Research 2022;14(2):1376-1383. (Full text, PDF)
Beiyun Wang, Yuan Zhong, Dong Huang, Jingbo Li: Macrophage autophagy regulated by miR-384-5p-mediated control of Beclin-1 plays a role in the development of atherosclerosis. American Journal of Translational Research 2016;8(2):606-614. (Full text, PDF)
Zhi Chen, Shuohui Gao, Dayv Wang, Defeng Song, Ye Feng: Colorectal cancer cells are resistant to anti-EGFR monoclonal antibody through adapted autophagy. American Journal of Translational Research 2016;8(2):1190-1196. (Full text, PDF)
Qichun Zhang, Huimin Bian, Liwei Guo, Huaxu Zhu: Pharmacologic preconditioning with berberine attenuating ischemia-induced apoptosis and promoting autophagy in neuron. American Journal of Translational Research 2016;8(2):1197-1207. (Full text, PDF)
Zhaohua Geng, Fei Xu, Yiguan Zhang: MiR-129-5p-mediated Beclin-1 suppression inhibits endothelial cell autophagy in atherosclerosis. American Journal of Translational Research 2016;8(4):1886-1894. (Full text, PDF)
Xin Gong, Huiqing Wang, Yongyi Ye, Yugao Shu, Yongwen Deng, Xiaozheng He, Guohui Lu, Shizhong Zhang: miR-124 regulates cell apoptosis and autophagy in dopaminergic neurons and protects them by regulating AMPK/mTOR pathway in Parkinson’s disease. American Journal of Translational Research 2016;8(5):2127-2137. (Full text, PDF)
Bisharad Anil Thapalia, Zhen Zhou, Xianhe Lin: Sauchinone augments cardiomyocyte viability by enhancing autophagy proteins -PI3K, ERK(1/2), AMPK and Beclin-1 during early ischemia-reperfusion injury in vitro. American Journal of Translational Research 2016;8(7):3251-3265. (Full text, PDF)
Qing Li, Qiu-Ting Dong, Yue-Jin Yang, Xia-Qiu Tian, Chen Jin, Pei-Sen Huang, Lei-Pei Jiang, Gui-Hao Chen: AMPK-mediated cardioprotection of atorvastatin relates to the reduction of apoptosis and activation of autophagy in infarcted rat hearts. American Journal of Translational Research 2016;8(10):4160-4171. (Full text, PDF)
Zuo-Qing Liu, Shan Zhao, Wen-Qin Fu: Insulin-like growth factor 1 antagonizes lumbar disc degeneration through enhanced autophagy. American Journal of Translational Research 2016;8(10):4346-4353. (Full text, PDF)
Jiabao Liu, Peng Wu, Yunle Wang, Yingqiang Du, Nan A, Shuiyuan Liu, Yiming Zhang, Ningtian Zhou, Zhihui Xu, Zhijian Yang: Ad-HGF improves the cardiac remodeling of rat following myocardial infarction by upregulating autophagy and necroptosis and inhibiting apoptosis. American Journal of Translational Research 2016;8(11):4605-4627. (Full text, PDF)
Zheng Liu, Feng Wang, Zhi-Wei Zhou, He-Chun Xia, Xin-Yu Wang, Yin-Xue Yang, Zhi-Xu He, Tao Sun, Shu-Feng Zhou: Alisertib induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt/mTOR- and p38 MAPK-mediated pathways in human glioblastoma cells. American Journal of Translational Research 2017;9(3):845-873. (Full text, PDF)
Yongyue Gao, Zong Zhuang, Shanting Gao, Xiang Li, Zihuan Zhang, Zhennan Ye, Liwen Li, Chao Tang, Mengliang Zhou, Xiao Han, Jie Li: Tetrahydrocurcumin reduces oxidative stress-induced apoptosis via the mitochondrial apoptotic pathway by modulating autophagy in rats after traumatic brain injury. American Journal of Translational Research 2017;9(3):887-899. (Full text, PDF)
Yan-Yan Li, Yin Xiang, Song Zhang, Yan Wang, Jie Yang, Wei Liu, Feng-Tai Xue: Thioredoxin-2 protects against oxygen-glucose deprivation/reperfusion injury by inhibiting autophagy and apoptosis in H9c2 cardiomyocytes. American Journal of Translational Research 2017;9(3):1471-1482. (Full text, PDF)
Zeming Liu, Wen Zeng, Shi Wang, Xiangwang Zhao, Yawen Guo, Pan Yu, Xingjie Yin, Chunping Liu, Tao Huang: A potential role for the Hippo pathway protein, YAP, in controlling proliferation, cell cycle progression, and autophagy in BCPAP and KI thyroid papillary carcinoma cells. American Journal of Translational Research 2017;9(7):3212-3223. (Full text, PDF)
Long Chen, Kailiang Zhou, Huanwen Chen, Shihen Li, Dingsheng Lin, Dongsheng Zhou: Calcitriol promotes survival of experimental random pattern flap via activation of autophagy. American Journal of Translational Research 2017;9(8):3642-3653. (Full text, PDF)
Jie Zhu, Ya Zheng, Haiyan Zhang, Jing Zhu, Hong Sun: Low concentration of chloroquine enhanced efficacy of cisplatin in the treatment of human ovarian cancer dependent on autophagy. American Journal of Translational Research 2017;9(9):4046-4058. (Full text, PDF)
Chun-Jie Gu , Jiao Cheng, Bing Zhang, Shao-Liang Yang, Feng Xie, Jian-Song Sun, Li-Qing Huang, Jin-Jin Yu, Ming-Qing Li: Protopanaxadiol and metformin synergistically inhibit estrogen-mediated proliferation and anti-autophagy effects in endometrial cancer cells. American Journal of Translational Research 2017;9(9):4071-4082. (Full text, PDF)
Li Wang, Dongliang Feng, Yuan Liu, Sen Li, Long Jiang, Zaiyun Long, Yamin Wu: Autophagy plays a protective role in motor neuron degeneration following spinal cord ischemia/reperfusion-induced spastic paralysis. American Journal of Translational Research 2017;9(9):4261-4270. (Full text, PDF)
Hui-Li Yang, Jie Mei, Kai-Kai Chang, Wen-Jie Zhou, Li-Qing Huang, Ming-Qing Li: Autophagy in endometriosis. American Journal of Translational Research 2017;9(11):4707-4725. (Full text, PDF)
Haoyuan Jia, Zhaofeng Liang, Xu Zhang, Juanjuan Wang, Wenrong Xu, Hui Qian: 14-3-3 proteins: an important regulator of autophagy in diseases. American Journal of Translational Research 2017;9(11):4738-4746. (Full text, PDF)
Bin Yu, Ming Ruan, Tao Liang, Shi-Wen Huang, Sheng-Jin Liu, Hai-Bo Cheng, Xiang-Chun Shen: Tetramethylpyrazine phosphate and borneol combination therapy synergistically attenuated ischemia-reperfusion injury of the hypothalamus and striatum via regulation of apoptosis and autophagy in a rat model. American Journal of Translational Research 2017;9(11):4807-4820. (Full text, PDF)
Jin-Ting Wang, Wen-Quan Xie, Fa-Quan Liu, Yue Bi, Xiong-Jie Zhu, Qi-En Wang, Yan-Fang Zheng: NADH protect against radiation enteritis by enhancing autophagy and inhibiting inflammation through PI3K/AKT pathway. American Journal of Translational Research 2018;10(6):1713-1721. (Full text, PDF)
Shuoqiang Hu, Shujun Cao, Zichuan Tong, Jinghua Liu: FGF21 protects myocardial ischemia-reperfusion injury through reduction of miR-145-mediated autophagy. American Journal of Translational Research 2018;10(11):3677-3688. (Full text, PDF)
Yongyong Ma, Zhouxiang Jin, Kang Yu, Qifa Liu: NVP-BEZ235-induced autophagy as a potential therapeutic approach for multiple myeloma. American Journal of Translational Research 2019;11(1):87-105. (Full text, PDF)
Can Lv, Zhan Zhang, Tong Zhao, Meng-Fei Han, Da-Peng Jia, Ling-Zi Su, Feng Huang, Fu-Zhe Wang, Fan-Fu Fang, Bai Li: The anti-tumour effect of Mel and its role in autophagy in human hepatocellular carcinoma cells. American Journal of Translational Research 2019;11(2):931-941. (Full text, PDF)
Lihua Qu, Chao Chen, Wei He, Yangye Chen, Yi Li, Yi Wen, Sichun Zhou, Yiqun Jiang, Xiaoping Yang, Ran Zhang, Li Shen: Glycyrrhizic acid ameliorates LPS-induced acute lung injury by regulating autophagy through the PI3K/AKT/mTOR pathway. American Journal of Translational Research 2019;11(4):2042-2055. (Full text, PDF)
Shuyi Xue, Yu Zhou, Jin Zhang, Zhuo Xiang, Yang Liu, Ting Miao, Guoxin Liu, Bangguo Liu, Xu Liu, Lixia Shen, Zhe Zhang, Mingchun Li, Qing Miao: Anemoside B4 exerts anti-cancer effect by inducing apoptosis and autophagy through inhibiton of PI3K/Akt/mTOR pathway in hepatocellular carcinoma. American Journal of Translational Research 2019;11(4):2580-2589. (Full text, PDF)
Haiying Tang, Xiaoyan Tan, Lei Zhu, Kairong Qin, Huan Gao, Hao Bai: Swimming prevents nonalcoholic fatty liver disease by reducing migration inhibitory factor through Akt suppression and autophagy activation. American Journal of Translational Research 2019;11(7):4315-4325. (Full text, PDF)
Weibin Wu, Zhen Shan, Rui Wang, Guangqi Chang, Mian Wang, Ridong Wu, Zilun Li, Chunxiang Zhang, Wen Li, Shenming Wang: Overexpression of miR-223 inhibits foam cell formation by inducing autophagy in vascular smooth muscle cells. American Journal of Translational Research 2019;11(7):4326-4336. (Full text, PDF)
Yecheng Li, Xiaodong Yang, Pingan Yao, Wenqi Shen, Yong Wu, Zhenyu Ye, Kui Zhao, Hanqing Chen, Jianping Cao, Chungen Xing: B7-H3 increases the radioresistance of gastric cancer cells through regulating baseline levels of cell autophagy. American Journal of Translational Research 2019;11(7):4438-4449. (Full text, PDF)
Yumei Li, Shengming Lin, Xiaoliang Xie, Haixia Zhu, Tianyou Fan, Song Wang: Highly enriched exosomal lncRNA OIP5-AS1 regulates osteosarcoma tumor angiogenesis and autophagy through miR-153 and ATG5. American Journal of Translational Research 2021;13(5):4211-4223. (Full text, PDF)
Xia Zhao, Bo Huang, Hao Wang, Na Ni, Fang He, Qing Liu, Deyao Shi, Connie Chen, Piao Zhao, Xi Wang, William Wagstaff, Mikhail Pakvasa, Andrew Blake Tucker, Michael J Lee, Jennifer Moriatis Wolf, Russell R Reid, Kelly Hynes, Jason Strelzow, Sherwin H Ho, Tengbo Yu, Jian Yang, Le Shen, Tong-Chuan He, Yongtao Zhang: A functional autophagy pathway is essential for BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs). American Journal of Translational Research 2021;13(5):4233-4250. (Full text, PDF)
Hao Zha, Yaodong Fan, Li Yang, Mei Yin, Wei Miao, Jin He, Ying Wang: Autophagy protects against cerebral ischemic reperfusion injury by inhibiting neuroinflammation. American Journal of Translational Research 2021;13(5):4726-4737. (Full text, PDF)
Wenliang Chen, Zhuo Li, Junfang Duan, Yingtao Liu, Changzhong Fang, Zihao Bai: LncRNA SNHG6 inhibits autophagy of gastric carcinoma cells via PI3K/AKT/mTOR signaling pathway. American Journal of Translational Research 2022;14(5):2861-2873. (Full text, PDF)
Yu Chen, Hao Liu, Xueyang Zheng, Jiyuan Wang, Liming Wang, Jinghui Yang: SIRT1 ameliorates renal ischemia-reperfusion injury through suppressing endoplasmic reticulum stress-mediated autophagy. American Journal of Translational Research 2022;14(5):3419-3429. (Full text, PDF)
Yibo Xu, Zhimeng Wang, Yakang Wang, Qiang Huang, Cheng Ren, Liang Sun, Qian Wang, Ming Li, Hongliang Liu, Zhong Li, Kun Zhang, Teng Ma, Yao Lu: Identification of differentially expressed autophagy genes associated with osteogenic differentiation in human bone marrow mesenchymal stem cells. American Journal of Translational Research 2022;14(8):5326-5342. (Full text, PDF)
Jie Zhang, Linlin Yao, Shaohua Li, Misbahul Ferdous, Peng Zhao: ER stress induces myocardial dysfunction and cardiac autophagy in Sestrin2 knockout mice. American Journal of Translational Research 2022;14(8):5800-5811. (Full text, PDF)
Xuehui Zhang, Naibin Yang, Lijiang Shao, Xuxia Chen, Xueqin Chen: Autophagy genes CCL2 and MYC are considered as potential biomarkers for pulmonary embolism. American Journal of Translational Research 2022;14(8):5896-5904. (Full text, PDF)
Wen-Jun Qin, Yi-Ge Su, Xiao-Long Ding, Ren Zhao, Zhi-Jun Zhao, Yan-Yang Wang: CDK4/6 inhibitor enhances the radiosensitization of esophageal squamous cell carcinoma (ESCC) by activating autophagy signaling via the suppression of mTOR. American Journal of Translational Research 2022;14(3):1616-1627. (Full text, PDF)
Haikang Liao, Zhenyou Zou, Weiqin Liu, Xuefeng Guo, Jinlu Xie, Liangxian Li, Xia Li, Xinying Gan, Xiansheng Huang, Juxia Liu, Wenyang Li, Hongji Zeng, Zheng Chen, Qiuhua Jiang, Hua Yao: Osteopontin-integrin signaling positively regulates neuroplasticity through enhancing neural autophagy in the peri-infarct area after ischemic stroke. American Journal of Translational Research 2022;14(11):7726-7743. (Full text, PDF)
Jian An, Wentao Wang, Yanqing Guo, Chao Wang, Qingbo Bao, Yongping Jia: Angiotensin receptor-neprilysin inhibitor attenuates ischemia-hypoxia-induced myocardial injury via inhibition of autophagy. American Journal of Translational Research 2022;14(12):8611-8620. (Full text, PDF)
Rong Li, Yanping Lin, Fengdi Hu, Yedan Liao, Jiadai Tang, Yan Shen, Heng Li, Jiangyan Guo, Lin Xie: LncRNA TEX41 regulates autophagy by increasing Runx2 expression in lung adenocarcinoma bone metastasis. American Journal of Translational Research 2023;15(2):949-966. (Full text, PDF)
Sheng Zhang, Kun Lin, Jun Qiu, Bin Feng, Juan Wang, Jia Li, Xia Peng, Renxin Ji, Longwei Qiao, Yuting Liang: Identification of potential key autophagy-related genes in asthma with bioinformatics approaches. American Journal of Translational Research 2022;14(10):7350-7361. (Full text, PDF, Supplementary Tables 1, 2)
Jianbin Sun, Wendi Zhai, Zheng Wang, Weijun An: Methotrexate plus electroacupuncture reduces autophagy in ankle synovial tissue in rats with rheumatoid arthritis. American Journal of Translational Research 2023;15(4):2747-2756. (Full text, PDF)
Qingqing Xia, Jie Li, Lingmin Zhang, Yingying Zhou, Zaixing Yang, Jing Xie: Increasing autophagy ameliorates all-trans-retinal-activated NLRP3 inflammasomes in human THP-1 macrophages. American Journal of Translational Research 2023;15(6):4380-4389. (Full text, PDF)
Jinjing Yang, Xiurui Ma, Dan Niu, Yu Sun, Xiaohong Chai, Yongzhi Deng, Jingping Wang, Jin Dong: PCSK9 inhibitors suppress oxidative stress and inflammation in atherosclerotic development by promoting macrophage autophagy. American Journal of Translational Research 2023;15(8):5129-5144. (Full text, PDF)
Yu Wang, Yuke Zhang, Hongxu Lu, Kai Liu, Wanxiong He, Zhiwei Pei, Jianzhong Wang: Integrative analysis of cellular autophagy-related genes in steroid-induced osteonecrosis of the femoral head. American Journal of Translational Research 2023;15(9):5850-5872. (Full text, PDF)
Fangfang Zhao, Wei Wei, Dongping Huang, Yi Guo: Knockdown of miR-27a reduces TGFβ-induced EMT and H2O2-induced oxidative stress through regulating mitochondrial autophagy. American Journal of Translational Research 2023;15(10):6071-6082. (Full text, PDF)
Lingji Li, Ranran Xi, Bing Gao, Yonglei Zeng, Qiang Ma, Tiantian Gong, Jing Wang: Research progress of autophagy in heart failure. American Journal of Translational Research 2024;16(5):1991-2000. (Full text, PDF)
Weizhi Yin, Meilan Liu, Zhiqi Zheng, Zhaoning Liu, Zhitao Men: Evaluation of the clinical efficacy of Zhuanggu Zhitong Recipe in treatment of postmenopausal osteoporosis and its correlation with the AMPK/mTOR autophagy signaling pathway. American Journal of Translational Research 2024;16(9):4301-4319. (Full text, PDF)
Fubo Tian, Yu Cao, Yaojun Lu, Zixuan Ren, Shen Sun, Jianhua Xia: Effects of warm silver needle acupuncture combined with myofascial trigger point intervention on peripheral neutrophil autophagy and alleviation of chronic pelvic pain in women. American Journal of Translational Research 2025;17(4):2885-2897. (Full text, PDF)
Yuanxin Huang, Hai Xu, Dongmei Mao, Jinqi Shao, Lili Deng, Tingyu Wang, Zeqing Liao, Xue Li, Yutao Chen, Jing Yao, Zhongjie Zhang: Effects of stellate ganglion block on inflammation and autophagy of spinal cord neurons in rats with neuropathic pain after spinal cord injury. American Journal of Translational Research 2025;17(4):3063-3073. (Full text, PDF)
Yifan Huang, Bin Yang, Xiaopeng Liu, Xiaozhan Yang, Jiankai Gao, Ruifang Cui, Rui Zhang, Sisen Zhang: Mechanisms and therapeutic potential of hyperbaric oxygen inducing autophagy in cerebral ischemia-reperfusion injury. American Journal of Translational Research 2025;17(11):9084-9091. (Full text, PDF)
Xiaoqin Zheng, Hehe Chen: Roles of autophagy in sepsis-induced myocardial dysfunction: a comprehensive review. American Journal of Translational Research 2026;18(1):64-76. (Full text, PDF)
Dejiang Ji, Dan Yang, Yahong Feng, Xiaojing Zhang, Gaxi Ye: Acupuncture at "Baihui" and "Xuanli" attenuates intracerebral hemorrhage-induced brain injury by modulating autophagy and the PI3K/AKT signaling pathway in rats. American Journal of Translational Research 2026;18(3):1945-1958. (Full text, PDF)
Xin Dai, Lin Liu, Nana Guo, Chaokun Mao, Xuesen Yan: Cross-linked (R)-(+)-lipoic acid nanoparticles loaded with silibinin induce apoptosis and autophagy in glioblastoma cells. American Journal of Translational Research 2026;18(5):4265-4279. (Full text, PDF)
Minghua Shang, Jinyi Yu, Xingang Li: Brazilin induces apoptosis and autophagy in human glioblastoma cells via the PI3K/AKT/mTOR signaling pathway. American Journal of Translational Research 2026;18(5):4577-4592. (Full text, PDF)
