Marta De Donato, Mara Fanelli, Marisa Mariani, Giuseppina Raspaglio, Deep Pandya, Shiquan He, Paul Fiedler, Marco Petrillo, Giovanni Scambia, Cristiano Ferlini: Nek6 and Hif-1α cooperate with the cytoskeletal gateway of drug resistance to drive outcome in serous ovarian cancer. Am J Cancer Res 2015;5(6):1862-1877. (Full text, PDF)
Shaolin Tao, Jie Yu, Yi Xu, Bo Deng, Tianyu Sun, Pingping Hu, Zhuanqin Wei, Jingge Zhang, Ruwen Wang, Chunmeng Shi, Qunyou Tan: PC4 induces lymphangiogenesis dependent VEGF-C/VEGF-D/VEGFR-3 axis activation in lung adenocarcinoma. Am J Cancer Res 2015;5(6):1878-1889. (Full text, PDF)
Liling Li, Fang Cao, Baoan Liu, Xiaojuan Luo, Xin Ma, Zhongliang Hu: TGF-β induces fascin expression in gastric cancer via phosphorylation of smad3 linker area. Am J Cancer Res 2015;5(6):1890-1896. (Full text, PDF)
Yuwen Cao, Yixiao Li, Na Zhang, Jianming Hu, Liang Yin, Zemin Pan, Yucong Li, Xiaoming Du, Wenjie Zhang, Feng Li: Quantitative DNA hypomethylation of ligand Jagged1 and receptor Notch1 signifies occurrence and progression of breast carcinoma. Am J Cancer Res 2015;5(6):1897-1910. (Full text, PDF)
Guohui Wu, Xiaoli Fan, Li Sun: Silencing of Wnt10B reduces viability of heptocellular carcinoma HepG2 cells. Am J Cancer Res 2015;5(6):1911-1920. (Full text, PDF)
Carolien Boeckx, Lina Blockx, Ken Op de Beeck, Ridha Limame, Guy Van Camp, Marc Peeters, Jan B Vermorken, Pol Specenier, An Wouters, Marc Baay, Filip Lardon: Establishment and characterization of cetuximab resistant head and neck squamous cell carcinoma cell lines: focus on the contribution of the AP-1 transcription factor. Am J Cancer Res 2015;5(6):1921-1938. (Full text, PDF)
Langyong Mao, Yan Zhang, Xiaolong Deng, Wenjuan Mo, Yao Yu, Hong Lu: Transcription factor KLF4 regulates microRNA-544 that targets YWHAZ in cervical cancer. Am J Cancer Res 2015;5(6):1939-1953. (Full text, PDF)
Ivana Kurelac, Dario de Biase, Claudia Calabrese, Claudio Ceccarelli, Charlotte KY Ng, Raymond Lim, Alan MacKay, Britta Weigelt, Anna Maria Porcelli, Jorge S Reis-Filho, Giovanni Tallini, Giuseppe Gasparre: High-resolution genomic profiling of thyroid lesions uncovers preferential copy number gains affecting mitochondrial biogenesis loci in the oncocytic variants. Am J Cancer Res 2015;5(6):1954-1971. (Full text, PDF)
Fanny Dubois, Cédric Leroy, Valérie Simon, Christine Benistant, Serge Roche: YES oncogenic activity is specified by its SH4 domain and regulates RAS/MAPK signaling in colon carcinoma cells. Am J Cancer Res 2015;5(6):1972-1987. (Full text, PDF, Supplementary Data)
Zhengting Wang, Liying Wang, Jiajia Hu, Rong Fan, Jie Zhou, Lei Wang, Jie Zhong: RARRES3 suppressed metastasis through suppression of MTDH to regulate epithelial-mesenchymal transition in colorectal cancer. Am J Cancer Res 2015;5(6):1988-1999. (Full text, PDF)
Da-Jian Zhu, Xiao-Wu Chen, Wei-Jie Zhang, Jia-Zhi Wang, Man-Zhao Ouyang, Qiang Zhong, Chang-Chun Liu: Twist1 is a potential prognostic marker for colorectal cancer and associated with chemoresistance. Am J Cancer Res 2015;5(6):2000-2011. (Full text, PDF)
Chao Jiang, Qiong Wang, Zhe Xu, Wei-Su Li, Che Chen, Xue-Quan Yao, Fu-Kun Liu: Cyclooxygenase-2 knockdown using retinoic acid chalcone (RAC), a promising therapeutic strategy for colon cancer. Am J Cancer Res 2015;5(6):2012-2021. (Full text, PDF)
Qingguo Li, Jitao Wu, Ping Wei, Ye Xu, Changhua Zhuo, Yuwei Wang, Dawei Li, Sanjun Cai: Overexpression of forkhead Box C2 promotes tumor metastasis and indicates poor prognosis in colon cancer via regulating epithelial-mesenchymal transition. Am J Cancer Res 2015;5(6):2022-2034. (Full text, PDF)
Stephanie Booy, Casper HJ van Eijck, Joseph AMJL Janssen, Fadime Dogan, Peter M van Koetsveld, Leo J Hofland: IFN-β is a potent inhibitor of insulin and insulin like growth factor stimulated proliferation and migration in human pancreatic cancer cells. Am J Cancer Res 2015;5(6):2035-2046. (Full text, PDF)
Jing-Dong Zhou, Dong-Ming Yao, Ying-Ying Zhang, Ji-Chun Ma, Xiang-Mei Wen, Jing Yang, Hong Guo, Qin Chen, Jiang Lin, Jun Qian: GPX3 hypermethylation serves as an independent prognostic biomarker in non-M3 acute myeloid leukemia. Am J Cancer Res 2015;5(6):2047-2055. (Full text, PDF)
Peng Zhou, Wei-Guo Chen, Xiao-Wei Li: MicroRNA-143 acts as a tumor suppressor by targeting hexokinase 2 in human prostate cancer. Am J Cancer Res 2015;5(6):2056-2063. (Full text, PDF)
Feifei Teng, Dianbin Mu, Xiangjiao Meng, Li Kong, Hui Zhu, Sujing Liu, Jianbo Zhang, Jinming Yu: Tumor infiltrating lymphocytes (TILs) before and after neoadjuvant chemoradiotherapy and its clinical utility for rectal cancer. Am J Cancer Res 2015;5(6):2064-2074. (Full text, PDF)
Long Jiang, Shanshan Jiang, Yongbin Lin, Dongrong Situ, Han Yang, Yuanfang Li, Hao Long, Zhiwei Zhou: Significance of local treatment in patients with metastatic soft tissue sarcoma. Am J Cancer Res 2015;5(6):2075-2082. (Full text, PDF)
John Bunni, Golda Shelley-Fraser, Kirsty Stevenson, Sebastian Oltean, Andy Salmon, Steven J Harper, James G Carter, David O Bates: Circulating levels of anti-angiogenic VEGF-A isoform (VEGF-Axxxb) in colorectal cancer patients predicts tumour VEGF-A ratios. Am J Cancer Res 2015;5(6):2083-2089. (Full text, PDF)
Huan Feng, Wei Zhang, Jiajun Li, Xiaozhe Lu: Different patterns in the prognostic value of age for bladder cancer-specific survival depending on tumor stages. Am J Cancer Res 2015;5(6):2090-2097. (Full text, PDF)
Qiang Guo, Fen Ning, Rui Fang, Hong-Sheng Wang, Ge Zhang, Mei-Yu Quan, Shao-Hui Cai, Jun Du: Endogenous Nodal promotes melanoma undergoing epithelial-mesenchymal transition via Snail and Slug in vitro and in vivo. Am J Cancer Res 2015;5(6):2098-2112. (Full text, PDF)