Shan-Shan Guo, Bi-Xia Li, Duo-Bing Zou, Shu-Jun Yang, Li-Xia Sheng, Gui-Fang Ouyang, Qi-Tian Mu, He Huang: Tip of the iceberg: roles of circRNAs in hematological malignancies. Am J Cancer Res 2020;10(2):367-382. (Full text, PDF)
Zhongbo Zhu, Xiangdong Zhu, Shuo Yang, Zhanzi Guo, Kangle Li, Cuicui Ren, Yunyun Zhou, Jianwei Dou: Yin-yang effect of tumour cells in breast cancer: from mechanism of crosstalk between tumour-associated macrophages and cancer-associated adipocytes. Am J Cancer Res 2020;10(2):383-392. (Full text, PDF)
Ping Zhu, Jerry Yu, Ping Zhou: Role of tRNA-derived fragments in cancer: novel diagnostic and therapeutic targets tRFs in cancer. Am J Cancer Res 2020;10(2):393-402. (Full text, PDF)
Mengmeng Cheng, Yannan Jiang, Han Yang, Dongyao Zhao, Longyu Li, Xinyu Liu: FLNA promotes chemoresistance of colorectal cancer through inducing epithelial-mesenchymal transition and smad2 signaling pathway. Am J Cancer Res 2020;10(2):403-423. (Full text, PDF)
Soon-Kyung Hwang, Yun-Jeong Jeong, Young-Chae Chang: PDCD4 inhibits lung tumorigenesis by the suppressing p62-Nrf2 signaling pathway and upregulating Keap1 expression. Am J Cancer Res 2020;10(2):424-439. (Full text, PDF)
Kiichiro Baba, Motoo Nomura, Shinya Ohashi, Takuya Hiratsuka, Yukie Nakai, Tomoki Saito, Yuki Kondo, Keita Fukuyama, Osamu Kikuchi, Atsushi Yamada, Junichi Matsubara, Kenshiro Hirohashi, Yosuke Mitani, Ayaka Mizumoto, Manabu Muto: Experimental model for the irradiation-mediated abscopal effect and factors influencing this effect. Am J Cancer Res 2020;10(2):440-453. (Full text, PDF)
Houyu Ju, Zhenrong Hu, Yusheng Lu, Yunteng Wu, Liming Zhang, Dongliang Wei, Wei Guo, Weiya Xia, Shuli Liu, Guoxin Ren, Jingzhou Hu: TLR4 activation leads to anti-EGFR therapy resistance in head and neck squamous cell carcinoma. Am J Cancer Res 2020;10(2):454-472. (Full text, PDF)
Deqiang Fu, Jichun Wu, Jinzhi Lai, Ying Liu, Linlin Zhou, Ling Chen, Qiuyu Zhang: T cell recruitment triggered by optimal dose platinum compounds contributes to the therapeutic efficacy of sequential PD-1 blockade in a mouse model of colon cancer. Am J Cancer Res 2020;10(2):473-490. (Full text, PDF)
Xiaowei Wu, Yu Deng, Yukun Zu, Jin Yin: Histone demethylase KDM4C activates HIF1α/VEGFA signaling through the costimulatory factor STAT3 in NSCLC. Am J Cancer Res 2020;10(2):491-506. (Full text, PDF)
Juan Li, Jie Liu, Riqi Wang, He Chen, Cui Li, Minggang Zhao, Fang He, Yaochun Wang, Peijun Liu: Trifluridine selectively inhibits cell growth and induces cell apoptosis of triple-negative breast cancer. Am J Cancer Res 2020;10(2):507-522. (Full text, PDF)
Chong Yang, Shikai Zhu, Hongji Yang, Ping Fan, Zibo Meng, Jingyuan Zhao, Kun Zhang, Xin Jin: FBP1 binds to the bromodomain of BRD4 to inhibit pancreatic cancer progression. Am J Cancer Res 2020;10(2):523-535. (Full text, PDF)
Peiqiang Yi, Huan Li, Yuehua Fang, Jun Su, Cheng Xu, Lu Cao, Min Li, Jiayi Chen: Administration of trastuzumab with heart irradiation induced acute cardiotoxicity in mice. Am J Cancer Res 2020;10(2):536-544. (Full text, PDF)
Xin Zhang, Kaikai Ding, Jianxiong Ji, Himalaya Parajuli, Synnøve Nymark Aasen, Heidi Espedal, Bin Huang, Anjing Chen, Jian Wang, Xingang Li, Frits Thorsen: Trifluoperazine prolongs the survival of experimental brain metastases by STAT3-dependent lysosomal membrane permeabilization. Am J Cancer Res 2020;10(2):545-563. (Full text, PDF)
Xian Sun, Chia-Wei Li, Wei-Jan Wang, Mei-Kuang Chen, Hui Li, Yun-Ju Lai, Jennifer L Hsu, Paul B Koller, Li-Chuan Chan, Pei-Chih Lee, Fang-Ju Cheng, Clinton Yam, Gong-Yan Chen, Mien-Chie Hung: Inhibition of c-MET upregulates PD-L1 expression in lung adenocarcinoma. Am J Cancer Res 2020;10(2):564-571. (Full text, PDF)
Francesca Ricci, Federica Guffanti, Roberta Affatato, Laura Brunelli, Pastorelli Roberta, Robert Fruscio, Patrizia Perego, Maria Rosa Bani, Giovanna Chiorino, Andrea Rinaldi, Francesco Bertoni, Maddalena Fratelli, Giovanna Damia: Establishment of patient-derived tumor xenograft models of mucinous ovarian cancer. Am J Cancer Res 2020;10(2):572-580. (Full text, PDF)
Kuniaki Nerome, Taku Ito-Kureha, Tiziana Paganini, Takao Fukuda, Yasuhiro Igarashi, Hiroto Ashitomi, Shinya Ikematsu, Tadashi Yamamoto: Potent and broad anticancer activities of leaf extracts from Melia azedarach L. of the subtropical Okinawa islands. Am J Cancer Res 2020;10(2):581-594. (Full text, PDF)
Shizhen Ding, Dandan Wu, Quotao Lu, Li Qian, Yanbing Ding, George Liu, Xiaoqin Jia, Yu Zhang, Weiming Xiao, Weijuan Gong: Angiopoietin-like 4 deficiency upregulates macrophage function through the dysregulation of cell-intrinsic fatty acid metabolism. Am J Cancer Res 2020;10(2):595-609. (Full text, PDF)
Dongying Wang, Jiaxing He, Junxue Dong, Thomas F Meyer, Tianmin Xu: The HIPPO pathway in gynecological malignancies. Am J Cancer Res 2020;10(2):610-629. (Full text, PDF)
Wei Hu, Fengqi Yan, Yi Ru, Mingyuan Xia, Guang Yan, Mei Zhang, He Wang, Guojun Wu, Libo Yao, Lan Shen, Xia Li, Qinhao Wang: MIIP inhibits EMT and cell invasion in prostate cancer through miR-181a/b-5p-KLF17 axis. Am J Cancer Res 2020;10(2):630-647. (Full text, PDF)
Yu-Yi Chu, Clinton Yam, Mei-Kuang Chen, Li-Chuan Chan, Min Xiao, Yong-Kun Wei, Hirohito Yamaguchi, Pei-Chih Lee, Ye Han, Lei Nie, Xian Sun, Stacy L Moulder, Kenneth R Hess, Bin Wang, Jennifer L Hsu, Gabriel N Hortobagyi, Jennifer Litton, Jeffrey T Chang, Mien-Chie Hung: Blocking c-Met and EGFR reverses acquired resistance of PARP inhibitors in triple-negative breast cancer. Am J Cancer Res 2020;10(2):648-661. (Full text, PDF)
Jin Chen, Qiu-Meng Liu, Peng-Chen Du, Deng Ning, Jie Mo, Hai-Dan Zhu, Chao Wang, Qian-Yun Ge, Qi Cheng, Xue-Wu Zhang, Ya-Wei Fan, Hui-Fang Liang, Liang Chu, Xiao-Ping Chen, Bi-Xiang Zhang, Li Jiang: Type-2 11β-hydroxysteroid dehydrogenase promotes the metastasis of colorectal cancer via the Fgfbp1-AKT pathway. Am J Cancer Res 2020;10(2):662-673. (Full text, PDF)
Monrat Chulanetra, Atthapan Morchang, Elias Sayour, Lamis Eldjerou, Rowan Milner, Joanne Lagmay, Matt Cascio, Brian Stover, William Slayton, Wanpen Chaicumpa, Pa-Thai Yenchitsomanus, Lung-Ji Chang: GD2 chimeric antigen receptor modified T cells in synergy with sub-toxic level of doxorubicin targeting osteosarcomas. Am J Cancer Res 2020;10(2):674-687. (Full text, PDF)
Hongzhi Li, Weihua Yuan, Shufang Bin, Guang Wu, Panyuan Li, Min Liu, Jifeng Yang, Xiang Li, Kaiyan Yang, Haihua Gu: Overcome trastuzumab resistance of breast cancer using anti-HER2 chimeric antigen receptor T cells and PD1 blockade. Am J Cancer Res 2020;10(2):688-703. (Full text, PDF)