Suzhu Chen, Taiping Li, Lijuan Meng, Kangsheng Liu: Advances in immunotherapy and molecular targeted therapy of gestational trophoblastic tumor: current practice and future perspectives. Am J Cancer Res 2022;12(6):2422-2432. (Full text, PDF)
Yang Liu, Yang Zhang, Bin Zhu, Wenyun Xu, Yi Yang, Zui Zou: Development of endotracheal intubation devices for patients with tumors. Am J Cancer Res 2022;12(6):2433-2446. (Full text, PDF)
Xingyu Liu, Huifang Xing, Baoxing Liu: Current status and future perspectives of immune checkpoint inhibitors in extensive-stage small cell lung cancer. Am J Cancer Res 2022;12(6):2447-2464. (Full text, PDF)
Miao Liu, Ai Shen, Yongbo Zheng, Xiong Chen, Leilei Wang, Ting Li, Xin Ouyang, Xian Yu, Hao Sun, Xiaohou Wu: Long non-coding RNA lncHUPC1 induced by FOXA1 promotes tumor progression by inhibiting apoptosis via miR-133b/SDCCAG3 in prostate cancer. Am J Cancer Res 2022;12(6):2465-2491. (Full text, PDF)
Siwen Yang, Yunkun Zhang, Chunmei Guo, Rui Liu, Maroua Elkharti, Zhenhua Ge, Qinlong Liu, Shuqing Liu, Ming-Zhong Sun: The homeostatic malfunction of a novel feedback pathway formed by lncRNA021545, miR-330-3p and epiregulin contributes in hepatocarcinoma progression via mediating epithelial-mesenchymal transition. Am J Cancer Res 2022;12(6):2492-2525. (Full text, PDF)
Migl? Paškevi?i: Effect of natural flavonoids to reverse P-glycoprotein-related multidrug resistance in breast cancer cell cultures. Am J Cancer Res 2022;12(6):2526-2538. (Full text, PDF)
Guohua Gong, Jikai She, Danni Fu, Dong Zhen, Bin Zhang: CircUBR5 acts as a ceRNA for miR-1179 to up-regulate UBR5 and to promote malignancy of triple-negative breast cancer. Am J Cancer Res 2022;12(6):2539-2557. (Full text, PDF)
Chuanhong Zhong, Lilei Peng, Bei Tao, Senlin Yin, Liang Lyu, Hao Ding, Xiaobo Yang, Tangming Peng, Haiping He, Peizhi Zhou: TDO2 and tryptophan metabolites promote kynurenine/AhR signals to facilitate glioma progression and immunosuppression. Am J Cancer Res 2022;12(6):2558-2575. (Full text, PDF)
Yihua Lai, Hsiuhui Chang, Hueiwen Chen, Geechen Chang, Jeremy JW Chen: Peruvoside is a novel Src inhibitor that suppresses NSCLC cell growth and motility by downregulating multiple Src-EGFR-related pathways. Am J Cancer Res 2022;12(6):2576-2593. (Full text, PDF)
Seung-Youn Jung, Jeong-In Park, Jae-Hoon Jeong, Kyung-Hee Song, Jiyeon Ahn, Sang-Gu Hwang, Jaesung Kim, Jong-Kuk Park, Dae-Seog Lim, Jie-Young Song: Receptor interacting protein 1 knockdown induces cell death in liver cancer by suppressing STAT3/ATR activation in a p53-dependent manner. Am J Cancer Res 2022;12(6):2594-2611. (Full text, PDF)
Jinrong He, Shanshan Chen, Tong Yu, Weiqun Chen, Jin Huang, Caixia Peng, Yu Ding: Harmine suppresses breast cancer cell migration and invasion by regulating TAZ-mediated epithelial-mesenchymal transition. Am J Cancer Res 2022;12(6):2612-2626. (Full text, PDF)
Masanori Oshi, Arya Mariam Roy, Shipra Gandhi, Yoshihisa Tokumaru, Li Yan, Akimitsu Yamada, Itaru Endo, Kazuaki Takabe: The clinical relevance of unfolded protein response signaling in breast cancer. Am J Cancer Res 2022;12(6):2627-2640. (Full text, PDF)
Ke Xia, Wenqiang Huang, Xiaoyun Zhao, Xiaoqin Huang, Yan Chen, Li Yu, Yongjun Tan: Increased FOXA1 levels induce apoptosis and inhibit proliferation in FOXA1-low expressing basal breast cancer cells. Am J Cancer Res 2022;12(6):2641-2658. (Full text, PDF, Tables S1, S2)
Ding-Sen Huang, Ting-Ting Liu, Wei-Ting Lu, Chih-Chi Wang, Chih-Che Lin, Chee-Chen Yong, Kuang-Den Chen, Yueh-Wei Liu, Yuan-Hung Kuo, Yi-Hao Yen, Tsung-Hui Hu, Ming-Chao Tsai: Comparison of portal and capsular microscopic vascular invasion in the outcomes of early HCC after curative resection. Am J Cancer Res 2022;12(6):2659-2672. (Full text, PDF)
Won Seok Lee, Eun Ho Kim: Combination therapy of Doxorubicin with TTFields and radiation: newer approaches to combat lung cancer. Am J Cancer Res 2022;12(6):2673-2685. (Full text, PDF)
Zhi Zheng, Yuxi Shang, Rui Xu, Xiaosheng Yan, Xi Wang, Jun Cai, Zhigang Bai, Xiaoye Liu, Jie Yin, Jun Zhang, Zhongtao Zhang: Ubiquitin specific peptidase 38 promotes the progression of gastric cancer through upregulation of fatty acid synthase. Am J Cancer Res 2022;12(6):2686-2696. (Full text, PDF)
Can Cui, Yuting Pan, Chengqian Zhang, Darong Zhu, Ying Xuan, Piliang Hao, Xisong Ke, Xianglian Zhou, Yi Qu: Eltrombopag binds SDC4 directly and enhances MAPK signaling and macropinocytosis in cancer cells. Am J Cancer Res 2022;12(6):2697-2710. (Full text, PDF)
Cheng-Rui Zhong, Ji-Liang Qiu, Yi-Chuan Yuan, Zhi-Yu Qiu, Kai Li, Chen-Wei Wang, Yun-Xing Shi, Ke-Ren Li, Zhu Lin, Zhen-Kun Huang, Wei He, Bin-Kui Li, Yun-Fei Yuan: A detailed assessment of liver function in patients with hepatocellular carcinoma via the modified albumin-bilirubin (mALBI) grade. Am J Cancer Res 2022;12(6):2711-2720. (Full text, PDF)
Yanyan Jing, Jie Zhao, Zhen Yang, Senbang Yao, Lingxue Tang, Wen Li, Sheng Yu, Huaidong Cheng: Managing cancer and living meaningfully (CALM) as an intervention for severe fatigue in gastrointestinal cancer survivors. Am J Cancer Res 2022;12(6):2721-2732. (Full text, PDF)
Xuesong Zhao, Jaya Julie Joshi, Daniel Aird, Craig Karr, Kun Yu, Chialing Huang, Federico Colombo, Milena Virrankoski, Sudeep Prajapati, Anand Selvaraj: Combined inhibition of FGFR4 and VEGFR signaling enhances efficacy in FGF19 driven hepatocellular carcinoma. Am J Cancer Res 2022;12(6):2733-2743. (Full text, PDF)
Chuanxin Xia, Lei Qin, Yinzhi Wang, Ling Yao, Benchang Shia, Szu-Yuan Wu: Risk factors and specific cancer types of second primary malignancies in patients with breast cancer receiving adjuvant radiotherapy: a case-control cohort study based on the SEER database. Am J Cancer Res 2022;12(6):2744-2756. (Full text, PDF)
Xiaodong Qu, Xingyu Zhao, Yuhuan Liu, Na Wang, Luyao Zhang, Xiaojing Zhu, Qiang Dong, Junye Liu, Yongquan Shi: The clinicopathological characteristics of early-onset gastric cancer and its evolutionary trends: a retrospective study. Am J Cancer Res 2022;12(6):2757-2769. (Full text, PDF)
Yongsheng Pang, Aydin Eresen, Zigeng Zhang, Qiaoming Hou, Yining Wang, Vahid Yaghmai, Zhuoli Zhang: Adverse events of sorafenib in hepatocellular carcinoma treatment. Am J Cancer Res 2022;12(6):2770-2782. (Full text, PDF)
Xiao-Lin Hu, Xia-Tong Huang, Jia-Ni Zhang, Jie Liu, Li-Jun Wen, Xin Xu, Jue-Yu Zhou: Long noncoding RNA MIR210HG is induced by hypoxia-inducible factor 1α and promotes cervical cancer progression. Am J Cancer Res 2022;12(6):2783-2797. (Full text, PDF)
Jin Young Min, Gi Ho Lee, Tilak Khanal, Sun Woo Jin, Sang-Yeop Lee, Hyung Gyun Kim, Ju-Yong Hyon, Young-Ho Chung, Sang Keun Ha, Eun Hee Han, Hye Gwang Jeong: Upregulation of CYP1B1 by hypoxia is mediated by ERα activation in breast cancer cells. Am J Cancer Res 2022;12(6):2798-2816. (Full text, PDF)
Yang Dai, Jingcao Huang, Pu Kuang, Yiguo Hu, Qiang Zeng, Wanhua Zhang, He Li, Fangfang Wang, Tingting Guo, Dan Zhang, Dongni Yi, Yuhuan Zheng, Ting Liu: Dasatinib and interferon alpha synergistically induce pyroptosis-like cell death in philadelphia chromosome positive acute lymphoblastic leukemia. Am J Cancer Res 2022;12(6):2817-2832. (Full text, PDF)
Ruoxuan Hei, Jinnan Chen, Xiaojing Zhang, Huiqin Bian, Chen Chen, Xuan Wu, Tiaotiao Han, Yiming Zhang, Junxia Gu, Yaojuan Lu, Qiping Zheng: CircNRIP1 acts as a sponge of miR-1200 to suppress osteosarcoma progression via upregulation of MIA2. Am J Cancer Res 2022;12(6):2833-2849. (Full text, PDF)
Lindsey Buckingham, Tianran Hao, Jillian O’Donnell, Ziyi Zhao, Xin Zhang, Yali Fan, Wenchuan Sun, Yingao Zhang, Hongyan Suo, Angeles Alvarez Secord, Chunxiao Zhou, Victoria Bae-Jump: Ipatasertib, an oral AKT inhibitor, inhibits cell proliferation and migration, and induces apoptosis in serous endometrial cancer. Am J Cancer Res 2022;12(6):2850-2862. (Full text, PDF)
Jingwen Li, Fei Peng, He Huang, Zhen Cai: Trends in the risk of second primary malignances after non-Hodgkin’s lymphoma. Am J Cancer Res 2022;12(6):2863-2875. (Full text, PDF)
Hon-Yi Shi, King-The Lee, Chong-Chi Chiu, Jhi-Joung Wang, Ding-Ping Sun, Hao-Hsien Lee: 5-year recurrence prediction after hepatocellular carcinoma resection: deep learning vs. Cox regression models. Am J Cancer Res 2022;12(6):2876-2890. (Full text, PDF)
Hongzhi Li, Weihua Yuan, Shufang Bin, Guang Wu, Panyuan Li, Min Liu, Jifeng Yang, Xiang Li, Kaiyan Yang, Haihua Gu: Overcome trastuzumab resistance of breast cancer using anti-HER2 chimeric antigen receptor T cells and PD1 blockade: Am J Cancer Res. 2020; 10(2): 688-703. Am J Cancer Res 2022;12(6):2891-2892. (Full text, PDF)
Shijing Wang, Hui Wen, Wenyi Fei, Yuhong Zhao, Yuqi Feng, Lu Kuang, Min Wang, Min Wu: Two engineered site-specific antibody-drug conjugates, HLmD4 and HLvM4, have potent therapeutic activity in two DLL4-positive tumour xenograft models: Am J Cancer Res. 2020; 10(8): 2387-2408. Am J Cancer Res 2022;12(6):2893-2896. (Full text, PDF)
