Francisco S Chung, Jayson S Santiago, Miguel Francisco M De Jesus, Camille V Trinidad, Melvin Floyd E See: Disrupting P-glycoprotein function in clinical settings: what can we learn from the fundamental aspects of this transporter? Am J Cancer Res 2016;6(8):1583-1598. (Full text, PDF)
Collin M Labak, Paul Y Wang, Rishab Arora, Maheedhara R Guda, Swapna Asuthkar, Andrew J Tsung, Kiran K Velpula: Glucose transport: meeting the metabolic demands of cancer, and applications in glioblastoma treatment. Am J Cancer Res 2016;6(8):1599-1608. (Full text, PDF)
Katsuya Nakai, Mien-Chie Hung, Hirohito Yamaguchi: A perspective on anti-EGFR therapies targeting triple-negative breast cancer. Am J Cancer Res 2016;6(8):1609-1623. (Full text, PDF)
Bin Ai, Zhixin Bie, Shuai Zhang, Ailing Li: Paclitaxel targets VEGF-mediated angiogenesis in ovarian cancer treatment. Am J Cancer Res 2016;6(8):1624-1635. (Full text, PDF)
Hui-Min Sun, Yu-Shuai Mi, Fu-Dong Yu, Yang Han, Xi-Sheng Liu, Su Lu, Yu Zhang, Sen-Lin Zhao, Ling Ye, Ting-Ting Liu, Dao-Hua Yang, Xiao-Feng Sun, Xue-Bin Qin, Zong-Guang Zhou, Hua-Mei Tang, Zhi-Hai Peng: SERPINA4 is a novel independent prognostic indicator and a potential therapeutic target for colorectal cancer. Am J Cancer Res 2016;6(8):1636-1649. (Full text, PDF)
Xing Hua, Yu Xiao, Wenhai Pan, Meiyun Li, Xiaoxiao Huang, Zexiao Liao, Qi Xian, Lina Yu: miR-186 inhibits cell proliferation of prostate cancer by targeting GOLPH3. Am J Cancer Res 2016;6(8):1650-1660. (Full text, PDF)
Yao-Yu Hsieh, Hsiang-Ling Lo, Pei-Ming Yang: EZH2 inhibitors transcriptionally upregulate cytotoxic autophagy and cytoprotective unfolded protein response in human colorectal cancer cells. Am J Cancer Res 2016;6(8):1661-1680. (Full text, PDF)
Wei Wang, Wen Bin Liu, Da Bing Huang, Wei Jia, Chu Shu Ji, Bing Hu: Targeting PCDH20 gene by microRNA-122 confers 5-FU resistance in hepatic carcinoma. Am J Cancer Res 2016;6(8):1681-1694. (Full text, PDF)
Haiqian Liang, Renjie Wang, Ying Jin, Jianwei Li, Sai Zhang: MiR-422a acts as a tumor suppressor in glioblastoma by targeting PIK3CA. Am J Cancer Res 2016;6(8):1695-1707. (Full text, PDF, Supplementary Data)
Xianfang Liu, Zhenghua Lv, Jidong Zou, Xiuxiu Liu, Juke Ma, Jinhua Wang, Na Sa, Peihang Jing, Wei Xu: Afatinib down-regulates MCL-1 expression through the PERK-eIF2α-ATF4 axis and leads to apoptosis in head and neck squamous cell carcinoma. Am J Cancer Res 2016;6(8):1708-1719. (Full text, PDF)
Ivette J Suárez-Arroyo, Yismeilin R Feliz-Mosquea, Juliana Pérez-Laspiur, Rezina Arju, Shah Giashuddin, Gerónimo Maldonado-Martínez, Luis A Cubano, Robert J Schneider, Michelle M Martínez-Montemayor: The proteome signature of the inflammatory breast cancer plasma membrane identifies novel molecular markers of disease. Am J Cancer Res 2016;6(8):1720-1740. (Full text, PDF)
Ping Li, Yan-Fei Jia, Xiao-Li Ma, Yan Zheng, Yi Kong, Yao Zhang, Shuai Zong, Zhi-Tao Chen, Yun-Shan Wang: DEC2 suppresses tumor proliferation and metastasis by regulating ERK/NF-κB pathway in gastric cancer. Am J Cancer Res 2016;6(8):1741-1757. (Full text, PDF)
Jung-Hoo Hwang, Jong Cheon Joo, Dae Joon Kim, Eunbi Jo, Hwa-Seung Yoo, Kyung-Bok Lee, Soo Jung Park, Ik-Soon Jang: Cordycepin promotes apoptosis by modulating the ERK-JNK signaling pathway via DUSP5 in renal cancer cells. Am J Cancer Res 2016;6(8):1758-1771. (Full text, PDF)
Ahmet Imrali, Xueying Mao, Marc Yeste-Velasco, Jonathan Shamash, Yongjie Lu: Rapamycin inhibits prostate cancer cell growth through cyclin D1 and enhances the cytotoxic efficacy of cisplatin. Am J Cancer Res 2016;6(8):1772-1784. (Full text, PDF)
Chi-Hsiang Chiang, Pei-Yi Chu, Ming-Feng Hou, Wen-Chun Hung: MiR-182 promotes proliferation and invasion and elevates the HIF-1α-VEGF-A axis in breast cancer cells by targeting FBXW7. Am J Cancer Res 2016;6(8):1785-1798. (Full text, PDF)
Ana S Pires-Luís, Márcia Vieira-Coimbra, Maria João Ferreira, João Ramalho-Carvalho, Pedro Costa-Pinheiro, Luís Antunes, Paula C Dias, Francisco Lobo, Jorge Oliveira, Inês Graça, Rui Henrique, Carmen Jerónimo: Prognostic significance of MST1R dysregulation in renal cell tumors. Am J Cancer Res 2016;6(8):1799-1811. (Full text, PDF)
Ju-Chi Liu, Hsin Hsiu, Yi-Ping Hsu, Hung-Chi Tsai, Chung-Hsien Kuo: Changes in the spectral index of skin-surface laser Doppler signals of nude mice following the injection of CT26 tumor cells. Am J Cancer Res 2016;6(8):1812-1819. (Full text, PDF)
Wei Liu, Xue-Liang Fu, Jian-Yu Yang, Min-Wei Yang, Ling-Ye Tao, De-Jun Liu, Yan-Miao Huo, Jun-Feng Zhang, Rong Hua, Yong-Wei Sun: Elevated expression of CTHRC1 predicts unfavorable prognosis in patients with pancreatic ductal adenocarcinoma. Am J Cancer Res 2016;6(8):1820-1827. (Full text, PDF)
You-Kang Chang, Yu-Heng Lai, Yen Chu, Ming-Cheng Lee, Chun-Yao Huang, Semon Wu: Haptoglobin is a serological biomarker for adenocarcinoma lung cancer by using the ProteomeLab PF2D combined with mass spectrometry. Am J Cancer Res 2016;6(8):1828-1836. (Full text, PDF)
Wesley K Utomo, Vincent T Janmaat, Auke P Verhaar, Jérôme Cros, Philippe Lévy, Philippe Ruszniewski, Mirella S Vredenbregt-van den Berg, Guido Jenster, Marco J Bruno, Henri Braat, Gwenny M Fuhler, Maikel P Peppelenbosch: DNA integrity as biomarker in pancreatic cyst fluid. Am J Cancer Res 2016;6(8):1837-1841. (Full text, PDF)
