Estefania Carrasco-Garcia, Juliana C Santos, Idoia Garcia, Mitsue Brianti, Mikel García-Puga, José Jr Pedrazzoli, Ander Matheu, Marcelo L Ribeiro: Paradoxical role of SOX2 in gastric cancer. Am J Cancer Res 2016;6(4):701-713. (Full text, PDF)
Nandini Dey, Yuliang Sun, Jennifer H Carlson, Hui Wu, Xiaoqian Lin, Brian Leyland-Jones, Pradip De: Anti-tumor efficacy of BEZ235 is complemented by its anti-angiogenic effects via downregulation of PI3K-mTOR-HIF1alpha signaling in HER2-defined breast cancers. Am J Cancer Res 2016;6(4):714-746. (Full text, PDF)
Ling-Chu Chang, Yung-Luen Yu, Min-Tsang Hsieh, Sheng-Hung Wang, Ruey-Hwang Chou, Wei-Chien Huang, Hui-Yi Lin, Hsin-Yi Hung, Li-Jiau Huang, Sheng-Chu Kuo: A novel microtubule inhibitor, MT3-037, causes cancer cell apoptosis by inducing mitotic arrest and interfering with microtubule dynamics. Am J Cancer Res 2016;6(4):747-763. (Full text, PDF)
Yan Chen Wongworawat, Maria Filippova, Vonetta M Williams, Valery Filippov, Penelope J Duerksen-Hughes: Chronic oxidative stress increases the integration frequency of foreign DNA and human papillomavirus 16 in human keratinocytes. Am J Cancer Res 2016;6(4):764-780. (Full text, PDF)
Koji Tanaka, Kelly A Whelan, Prasanna M Chandramouleeswaran, Shingo Kagawa, Sabrina L Rustgi, Chiaki Noguchi, Manti Guha, Satish Srinivasan, Yusuke Amanuma, Shinya Ohashi, Manabu Muto, Andres J Klein-Szanto, Eishi Noguchi, Narayan G Avadhani, Hiroshi Nakagawa: ALDH2 modulates autophagy flux to regulate acetaldehyde-mediated toxicity thresholds. Am J Cancer Res 2016;6(4):781-796. (Full text, PDF)
Wei-Si Liu, Yi-Dong Liu, Qiang Fu, Wei-Juan Zhang, Le Xu, Yuan Chang, Jie-Jie Xu: Prognostic significance of ubiquinol-cytochrome c reductase hinge protein expression in patients with clear cell renal cell carcinoma. Am J Cancer Res 2016;6(4):797-805. (Full text, PDF)
Andreas Machl, Erik W Wilker, Hui Tian, Xiaohong Liu, Patricia Schroeder, Anderson Clark, Bayard R Huck: M2698 is a potent dual-inhibitor of p70S6K and Akt that affects tumor growth in mouse models of cancer and crosses the blood-brain barrier. Am J Cancer Res 2016;6(4):806-818. (Full text, PDF)
Jian-Ye Zhang, Min-Ting Lin, Ho-Yi Tung, Si-Li Tang, Tao Yi, Ya-Zhou Zhang, Yi-Na Tang, Zhong-Zhen Zhao, Hu-Biao Chen: Bruceine D induces apoptosis in human chronic myeloid leukemia K562 cells via mitochondrial pathway. Am J Cancer Res 2016;6(4):819-826. (Full text, PDF)
Mei-Kuang Chen, Mien-Chie Hung: Regulation of therapeutic resistance in cancers by receptor tyrosine kinases. Am J Cancer Res 2016;6(4):827-842. (Full text, PDF)
Xueping Lei, Minfeng Chen, Qiulin Nie, Jianyang Hu, Zhenjian Zhuo, Anita Yiu, Heru Chen, Nanhui Xu, Maohua Huang, Kaihe Ye, Liangliang Bai, Wencai Ye, Dongmei Zhang: In vitro and in vivo antiangiogenic activity of desacetylvinblastine monohydrazide through inhibition of VEGFR2 and Axl pathways. Am J Cancer Res 2016;6(4):843-858. (Full text, PDF)
Tokuhiro Chano, Sofia Avnet, Katsuyuki Kusuzaki, Gloria Bonuccelli, Pierre Sonveaux, Dante Rotili, Antonello Mai, Nicola Baldini: Tumour-specific metabolic adaptation to acidosis is coupled to epigenetic stability in osteosarcoma cells. Am J Cancer Res 2016;6(4):859-875. (Full text, PDF)
Shou-Hua Wang, Xiao-Cai Wu, Ming-Di Zhang, Ming-Zhe Weng, Di Zhou, Zhi-Wei Quan: Upregulation of H19 indicates a poor prognosis in gallbladder carcinoma and promotes epithelial-mesenchymal transition. Am J Cancer Res 2016;6(4):876-877. (Full text, PDF)
