Yingpu Li, Hao Wu, Qin Wang, Shouping Xu: ZNF217: the cerberus who fails to guard the gateway to lethal malignancy. Am J Cancer Res 2021;11(7):3378-3405. (Full text, PDF)
Jian Li: Targeting claudins in cancer: diagnosis, prognosis and therapy. Am J Cancer Res 2021;11(7):3406-3424. (Full text, PDF)
Tomasz Pienkowski, Tomasz Kowalczyk, Adam Kretowski, Michal Ciborowski: A review of gliomas-related proteins. Characteristics of potential biomarkers. Am J Cancer Res 2021;11(7):3425-3444. (Full text, PDF)
Youwen Chen, Rui Liu, Chenxi Li, Yurong Song, Guangzhi Liu, Qingcai Huang, Liuchunyang Yu, Dongjie Zhu, Cheng Lu, Aiping Lu, Linfu Li, Yuanyan Liu: Nab-paclitaxel promotes the cancer-immunity cycle as a potential immunomodulator. Am J Cancer Res 2021;11(7):3445-3460. (Full text, PDF)
Todd William Mudd, Achuta Kumar Guddati: Management of hepatotoxicity of chemotherapy and targeted agents. Am J Cancer Res 2021;11(7):3461-3474. (Full text, PDF)
Hagar A Abu Quora, Maram H Zahra, Samah El-Ghlban, Neha Nair, Said M Afify, Ghmkin Hassan, Hend M Nawara, Mona Sheta, Sadia Monzur, Xiaoying Fu, Amira Osman, Akimasa Seno, Masaharu Seno: Microenvironment of mammary fat pads affected the characteristics of the tumors derived from the induced cancer stem cells. Am J Cancer Res 2021;11(7):3475-3495. (Full text, PDF)
Xiaoqing Liu, Shuqi Wang, Hao Zheng, Qingying Liu, Tao Shen, Xiaoning Wang, Dongmei Ren: Epimedokoreanin C, a prenylated flavonoid isolated from Epimedium koreanum, induces non-apoptotic cell death with the characteristics of methuosis in lung cancer cells. Am J Cancer Res 2021;11(7):3496-3514. (Full text, PDF)
Yong Weon Yi, Na Young Park, Joo-In Park, Yeon-Sun Seong, Young Bin Hong: Doxycycline potentiates the anti-proliferation effects of gemcitabine in pancreatic cancer cells. Am J Cancer Res 2021;11(7):3515-3536. (Full text, PDF)
Ling Xin, Chang Liu, Yinhua Liu, Robert E Mansel, Fiona Ruge, Eleri Davies, Wen G Jiang, Tracey A Martin: SIKs suppress tumor function and regulate drug resistance in breast cancer. Am J Cancer Res 2021;11(7):3537-3557. (Full text, PDF)
Chiara Galimberti, Tiziana Piepoli, Ornella Letari, Roberto Artusi, Stefano Persiani, Gianfranco Caselli, Lucio C Rovati: CR13626: a novel oral brain penetrant tyrosine kinase inhibitor that reduces tumor growth and prolongs survival in a mouse model of glioblastoma. Am J Cancer Res 2021;11(7):3558-3574. (Full text, PDF)
Jie Lu, Shuang-Yu Liu, Jing Zhang, Guang-Ming Yang, Gui-Bin Gao, Nan-Nan Yu, Yan-Ping Li, Yi-Xiang Li, Zhong-Qi Ma, Yang Wang, Chun-Hua Lu: Inhibition of BAG3 enhances the anticancer effect of shikonin in hepatocellular carcinoma. Am J Cancer Res 2021;11(7):3575-3593. (Full text, PDF)
Xiaohui Tan, Shuchang Ren, Melinda Z Fu, Shuyang Ren, Canyuan Yang, Xiaoling Wu, Tao Chen, Patricia S Latham, Stephen J Meltzer, Sidney W Fu: microRNA-196b promotes esophageal squamous cell carcinogenesis and chemoradioresistance by inhibiting EPHA7, thereby restoring EPHA2 activity. Am J Cancer Res 2021;11(7):3594-3610. (Full text, PDF)
Masanori Oshi, Shipra Gandhi, Fernando A Angarita, Tae Hee Kim, Yoshihisa Tokumaru, Li Yan, Ryusei Matsuyama, Itaru Endo, Kazuaki Takabe: A novel five-gene score to predict complete pathological response to neoadjuvant chemotherapy in ER-positive/HER2-negative breast cancer. Am J Cancer Res 2021;11(7):3611-3627. (Full text, PDF)
Masanori Oshi, Tsutomu Kawaguchi, Li Yan, Xuan Peng, Qianya Qi, Wanqing Tian, Amy Schulze, Kerry-Ann McDonald, Sumana Narayanan, Jessica Young, Song Liu, Luc GT Morris, Timothy A Chan, Pawel Kalinski, Ryusei Matsuyama, Eigo Otsuji, Itaru Endo, Kazuaki Takabe: Immune cytolytic activity is associated with reduced intra-tumoral genetic heterogeneity and with better clinical outcomes in triple negative breast cancer. Am J Cancer Res 2021;11(7):3628-3644. (Full text, PDF)
Fanying Meng, Wan-Fen Li, Donald Jung, Chun-Chung Wang, Tianyang Qi, Chi-Sheng Shia, Ren-Yu Hsu, Yin-Cheng Hsieh, Jianxin Duan: A novel selective AKR1C3-activated prodrug AST-3424/OBI-3424 exhibits broad anti-tumor activity. Am J Cancer Res 2021;11(7):3645-3659. (Full text, PDF)
Xiaoyan Bai, Xiao Jiang, Yuting Liu, Yiting Wang, Xuewei Jiang, Guang Song, Hongmei Qiu, Qinggao Zhang: Krüppel-like factor 9 upregulates E-cadherin transcription and represses breast cancer invasion and metastasis. Am J Cancer Res 2021;11(7):3660-3673. (Full text, PDF)
Vijayashree Murthy, Masanori Oshi, Yoshihisa Tokumaru, Itaru Endo, Kazuaki Takabe: Increased apoptosis is associated with robust immune cell infiltration and cytolytic activity in breast cancer. Am J Cancer Res 2021;11(7):3674-3687. (Full text, PDF)
Arumugam Paramasivam, Rinku George, Jayaseelan Vijayashree Priyadharsini: Genomic and transcriptomic alterations in m6A regulatory genes are associated with tumorigenesis and poor prognosis in head and neck squamous cell carcinoma. Am J Cancer Res 2021;11(7):3688-3697. (Full text, PDF)
Christine Greil, Julia Felthaus, Marie Follo, Gabriele Ihorst, Daniel Ewerth, Julia Schüler, Dominik Schnerch, Justus Duyster, Monika Engelhardt, Ralph Wäsch: Targeting mitotic exit in solid tumors. Am J Cancer Res 2021;11(7):3698-3710. (Full text, PDF)
I-Cheng Lee, Hao-Jan Lei, Gar-Yang Chau, Yi-Chen Yeh, Chi-Jung Wu, Chien-Wei Su, Teh-Ia Huo, Yee Chao, Han-Chieh Lin, Ming-Chih Hou, Yi-Hsiang Huang: Predictors of long-term recurrence and survival after resection of HBV-related hepatocellular carcinoma: the role of HBsAg. Am J Cancer Res 2021;11(7):3711-3725. (Full text, PDF)
Ya-Ting Cheng, Wei Teng, Kar-Wai Lui, Yi-Chung Hsieh, Wei-Ting Chen, Chien-Hao Huang, Wen-Juei Jeng, Chien-Fu Hung, Chen-Chun Lin, Chun-Yen Lin, Shi-Ming Lin, I-Shyan Sheen: MELD score is the better predictor for 30-day mortality in patients with ruptured hepatocellular carcinoma treated by trans-arterial embolization. Am J Cancer Res 2021;11(7):3726-3734. (Full text, PDF)
Shruti Gupta, Shefali Jain, Justin Yeh, Achuta Kumar Guddati: Unequal allotment of patients in phase III oncology clinical trials. Am J Cancer Res 2021;11(7):3735-3741. (Full text, PDF)