Ying Wang, Di Zhang, Yayi Hou, Sunan Shen, Tingting Wang: The adaptor protein CARD9, from fungal immunity to tumorigenesis. Am J Cancer Res 2020;10(8):2203-2225. (Full text, PDF)
Yuting Zhan, Haihua Wang, Yue Ning, Hongmei Zheng, Sile Liu, Yang Yang, Ming Zhou, Songqing Fan: Understanding the roles of stress granule during chemotherapy for patients with malignant tumors. Am J Cancer Res 2020;10(8):2226-2241. (Full text, PDF)
Chaocai Zhang, Mingzhu Jin, Jiannong Zhao, Juxiang Chen, Weilin Jin: Organoid models of glioblastoma: advances, applications and challenges. Am J Cancer Res 2020;10(8):2242-2257. (Full text, PDF)
Shubham Dwivedi, Anand Krishnan: Neural invasion: a scenic trail for the nervous tumor and hidden therapeutic opportunity. Am J Cancer Res 2020;10(8):2258-2270. (Full text, PDF)
Qing Li, Honggang Yu: The role of non-H. pylori bacteria in the development of gastric cancer. Am J Cancer Res 2020;10(8):2271-2281. (Full text, PDF)
Wensi Zhao, Hu Qiu, Yi Gong, Chen Han, Shasha Ruan, Chenyu Wang, Jiamei Chen, Shaobo Ke, Wei Shi, Jing Wang, Qiuni Xu, Yan Li, Yuxia Shi, Qian Chen, Yongshun Chen: Clinical considerations for the management of cancer patients in the mitigation stage of the COVID-19 pandemic. Am J Cancer Res 2020;10(8):2282-2292. (Full text, PDF)
Longfei Liu, Xiaoping Yi, Can Lu, Lin Qi, Youming Zhang, Minghao Li, Qiao Xiao, Cikui Wang, Liang Zhang, Yingxian Pang, Yong Wang, Xiao Guan: Applications of radiomics in genitourinary tumors. Am J Cancer Res 2020;10(8):2293-2308. (Full text, PDF)
Ting Shi, Xianbo Huang, Lixia Zhu, Xueying Li, Li Li, Xiujin Ye: Adult Ph-positive acute lymphoblastic leukemia-current concepts in cytogenetic abnormalities and outcomes. Am J Cancer Res 2020;10(8):2309-2318. (Full text, PDF)
Jiaxin Fan, Yan Zhao, Hongling Yuan, Jinxiao Yang, Ting Li, Zhenting He, Xiaohou Wu, Chunli Luo: Phospholipase C-ε regulates bladder cancer cells via ATM/EXO1. Am J Cancer Res 2020;10(8):2319-2336. (Full text, PDF)
Yan-Jiun Huang, Tse-Hung Huang, Vijesh Kumar Yadav, Maryam Rachmawati Sumitra, David TW Tzeng, Po-Li Wei, Jing-Wen Shih, Alexander TH Wu: Preclinical investigation of ovatodiolide as a potential inhibitor of colon cancer stem cells via downregulating sphere-derived exosomal β-catenin/STAT3/miR-1246 cargoes. Am J Cancer Res 2020;10(8):2337-2354. (Full text, PDF)
Xiang Jiang, Yingyi Liu, Ganggang Wang, Ye Yao, Chengjie Mei, Xiaoling Wu, Weijie Ma, Yufeng Yuan: Up-regulation of CLIC1 activates MYC signaling and forms a positive feedback regulatory loop with MYC in Hepatocellular carcinoma. Am J Cancer Res 2020;10(8):2355-2370. (Full text, PDF)
Sei Sai, Eun Ho Kim, Guillaume Vares, Masao Suzuki, Dong Yu, Yoshiya Horimoto, Mitsuhiro Hayashi: Combination of carbon-ion beam and dual tyrosine kinase inhibitor, lapatinib, effectively destroys HER2 positive breast cancer stem-like cells. Am J Cancer Res 2020;10(8):2371-2386. (Full text, PDF)
Shijing Wang, Hui Wen, Wenyi Fei, Yuhong Zhao, Yuqi Feng, Lu Kuang, Min Wang, Min Wu: Two engineered site-specific antibody-drug conjugates, HLmD4 and HLvM4, have potent therapeutic activity in two DLL4-positive tumour xenograft models. Am J Cancer Res 2020;10(8):2387-2408. (Full text, PDF)
Man Kit Cheung, Grace Gar Lee Yue, Kei Yin Tsui, Adele Joyce Gomes, Hoi Shan Kwan, Philip Wai Yan Chiu, Clara Bik San Lau: Discovery of an interplay between the gut microbiota and esophageal squamous cell carcinoma in mice. Am J Cancer Res 2020;10(8):2409-2427. (Full text, PDF)
Dong Yuan, Yiyu Chen, Zhu Yang, Gang Li, Mingjun Wu, Jinyue Jiang, Dan Li, Qiubo Yu: SPOP attenuates migration and invasion of choriocarcinoma cells by promoting DHX9 degradation. Am J Cancer Res 2020;10(8):2428-2445. (Full text, PDF, Supplementary Materials 1, 2, 3)
Yu Li, Xing Xiao, Hengxing Chen, Zhen Chen, Kaishun Hu, Dong Yin: Transcription factor NFYA promotes G1/S cell cycle transition and cell proliferation by transactivating cyclin D1 and CDK4 in clear cell renal cell carcinoma. Am J Cancer Res 2020;10(8):2446-2463. (Full text, PDF)
Chenglong Zhao, Xiaopan Cai, Yao Wang, Dongsheng Wang, Ting Wang, Haiyi Gong, Haitao Sun, Qi Jia, Wang Zhou, Zhipeng Wu, Zhenxi Li , Jianru Xiao: NAT1 promotes osteolytic metastasis in luminal breast cancer by regulating the bone metastatic niche via NF-κB/IL-1B signaling pathway. Am J Cancer Res 2020;10(8):2464-2479. (Full text, PDF)
Kexin Li, Furong Huang, Yan Li, Dongdong Li, Hong Lin, Ruoxuan Ni, Qiao Zhang, Mei Zhao, Shengkai Huang, Liang Zou, Changzhi Huang: Stabilization of oncogenic transcripts by the IGF2BP3/ELAVL1 complex promotes tumorigenicity in colorectal cancer. Am J Cancer Res 2020;10(8):2480-2494. (Full text, PDF)
Rupesh Shrestha, Kumaravel Mohankumar, Stephen Safe: Bis-indole derived nuclear receptor 4A1 (NR4A1) antagonists inhibit TGFβ-induced invasion of embryonal rhabdomyosarcoma cells. Am J Cancer Res 2020;10(8):2495-2509. (Full text, PDF)
Lixin Liu, Yangjian Pan, Xiaoli Ren, Zhicheng Zeng, Jingbo Sun, Kun Zhou, Yunshi Liang, Feifei Wang, Yongrong Yan, Wenting Liao, Yanqing Ding, Xiaolong Liu, Li Liang: GFPT2 promotes metastasis and forms a positive feedback loop with p65 in colorectal cancer. Am J Cancer Res 2020;10(8):2510-2522. (Full text, PDF)
Takuro Goto, Eiji Kashiwagi, Guiyang Jiang, Yujiro Nagata, Yuki Teramoto, Alexander S Baras, Shinichi Yamashita, Akihiro Ito, Yoichi Arai, Hiroshi Miyamoto: Estrogen receptor-β signaling induces cisplatin resistance in bladder cancer. Am J Cancer Res 2020;10(8):2523-2534. (Full text, PDF)
Yu-Chuan Wang, Wen-Hao Yang, Chia-Shin Yang, Mei-Hui Hou, Chia-Ling Tsai, Yi-Zhen Chou, Mien-Chie Hung, Yeh Chen: Structural basis of SARS-CoV-2 main protease inhibition by a broad-spectrum anti-coronaviral drug. Am J Cancer Res 2020;10(8):2535-2545. (Full text, PDF)
Ramesh Anita, Arumugam Paramasivam, Jayaseelan Vijayashree Priyadharsini, Srinivasan Chitra: The m6A readers YTHDF1 and YTHDF3 aberrations associated with metastasis and predict poor prognosis in breast cancer patients. Am J Cancer Res 2020;10(8):2546-2554. (Full text, PDF)
Takashi Takeshita, Li Yan, Xuan Peng, Siker Kimbung, Thomas Hatschek, Ingrid A Hedenfalk, Omar M Rashid, Kazuaki Takabe: Transcriptomic and functional pathway features were associated with survival after pathological complete response to neoadjuvant chemotherapy in breast cancer. Am J Cancer Res 2020;10(8):2555-2569. (Full text, PDF)
Naokazu Chiba, Makoto Sunamura, Masashi Nakagawa, Itsuki Koganezawa, Kei Yokozuka, Toshimichi Kobayashi, Kosuke Hikita, Yosuke Ozawa, Masaaki Okihara, Toru Sano, Koichi Tomita, Rina Tsutsui, Masahiro Sugimoto, Shigeyuki Kawachi: Overexpression of hydroxyproline via EGLN/HIF1A is associated with distant metastasis in pancreatic cancer. Am J Cancer Res 2020;10(8):2570-2581. (Full text, PDF)
Dongfang Tang, Hongliang Liu, Yuchen Zhao, Danwen Qian, Sheng Luo, Edward F Jr Patz, Li Su, Sipeng Shen, David C ChristianI, Wen Gao, Qingyi Wei: Genetic variants of BIRC3 and NRG1 in the NLRP3 inflammasome pathway are associated with non-small cell lung cancer survival. Am J Cancer Res 2020;10(8):2582-2595. (Full text, PDF)
Margot De Marco, Antonia Falco, Michela Festa, Antonio Raffone, Lucia Sandullo, Alessandra Rosati, Francesca Reppucci, Anna Lisa Cammarota, Franca Esposito, Danilo Swann Matassa, Maria Pascale, Francesco Salzano, Rosanna Martinelli, Paolo Remondelli, Mario Capunzo, Antonio Mollo, Fulvio Zullo, Antonio Travaglino, Maurizio Guida, Liberato Marzullo: Different mechanisms underlie IL-6 release in chemosensitive and chemoresistant ovarian carcinoma cells. Am J Cancer Res 2020;10(8):2596-2602. (Full text, PDF)
Lihua Liu, Hongliang Liu, Sheng Luo, Edward F Jr Patz, Carolyn Glass, Li Su, Lijuan Lin, David C Christiani, Qingyi Wei: Novel genetic variants of SYK and ITGA1 related lymphangiogenesis signaling pathway predict non-small cell lung cancer survival. Am J Cancer Res 2020;10(8):2603-2616. (Full text, PDF)
Juan Cintrón-García, Achuta Kumar Guddati: Management of CNS toxicity of chemotherapy and targeted agents: 2020. Am J Cancer Res 2020;10(8):2617-2620. (Full text, PDF)
Cheng-Wei Chou, Ri-Yao Yang, Li-Chuan Chan, Ching-Fei Li, Linlin Sun, Heng-Huan Lee, Pei-Chih Lee, Yuh-Pyng Sher, Haoqiang Ying, Mien-Chie Hung: The stabilization of PD-L1 by the endoplasmic reticulum stress protein GRP78 in triple-negative breast cancer. Am J Cancer Res 2020;10(8):2621-2634. (Full text, PDF)
Yaohui Wang, Xi Zhang, Weimin Wang, Xiaoxia Xing, Sifan Wu, Yinying Dong, Yang You, Rongxin Chen, Zhenggang Ren, Weijian Guo, Jiefeng Cui, Wentao Li: Integrin αVβ5/Akt/Sp1 pathway participates in matrix stiffness-mediated effects on VEGFR2 upregulation in vascular endothelial cells. Am J Cancer Res 2020;10(8):2635-2648. (Full text, PDF)
Hassan Lemjabbar-Alaoui, Csaba J Peto, Yi-Wei Yang, David M Jablons: AMXI-5001, a novel dual parp1/2 and microtubule polymerization inhibitor for the treatment of human cancers. Am J Cancer Res 2020;10(8):2649-2676. (Full text, PDF)
Yael Nemlich, Michal J Besser, Jacob Schachter, Gal Markel: ADAR1 regulates melanoma cell invasiveness by controlling beta3-integrin via microRNA-30 family members. Am J Cancer Res 2020;10(8):2677-2686. (Full text, PDF)
Retraction: Upregulating miR-146a by physcion reverses multidrug resistance in human chronic myelogenous leukemia K562/ADM cells. Am J Cancer Res 2020;10(8):2687. (Full text, PDF)
Retraction: miR-429 mediates tumor growth and metastasis in colorectal cancer. Am J Cancer Res 2020;10(8):2688. (Full text, PDF)
Retraction: Aberrant miR-1246 expression promotes radioresistance in non-small cell lung cancer: a potential prognostic biomarker and radiotherapy sensitization target. Am J Cancer Res 2020;10(8):2689. (Full text, PDF)
