Susana Goncalves, Pei-Chieh Fong, Mariya Blokhina: Artificial intelligence for early diagnosis of lung cancer through incidental nodule detection in low- and middle-income countries-acceleration during the COVID-19 pandemic but here to stay. Am J Cancer Res 2022;12(1):1-16. (Full text, PDF)
Arathi Rajan, Geetu R Varghese, Induprabha Yadev, Jaimie Anandan, Neetha R Latha, Dipyaman Patra, Neethu Krishnan, Krithiga Kuppusamy, Arathy V Warrier, Satej Bhushan, Revathy Nadhan, Ram Mohan Ram Kumar, Priya Srinivas: Modulation of BRCA1 mediated DNA damage repair by deregulated ER-α signaling in breast cancers. Am J Cancer Res 2022;12(1):17-47. (Full text, PDF)
Wei Gao, Lingyin Hu, Minjuan Zhang, Shuai Liu, Shaowei Xu, Velda Ling-Yu Chow, Jimmy Yu-Wai Chan, Thian-Sze Wong: Mitochondrial DHODH regulates hypoxia-inducible factor 1 expression in OTSCC. Am J Cancer Res 2022;12(1):48-67. (Full text, PDF)
Sugandha Saxena, Caitlin Molczyk, Abhilasha Purohit, Evie Ehrhorn, Paran Goel, Dipakkumar R Prajapati, Pranita Atri, Sukhwinder Kaur, Paul M Grandgenett, Michael A Hollingsworth, Surinder K Batra, Rakesh K Singh: Differential expression profile of CXC-receptor-2 ligands as potential biomarkers in pancreatic ductal adenocarcinoma. Am J Cancer Res 2022;12(1):68-90. (Full text, PDF)
Jing Peng, Wencan Li, Nianxi Tan, Xihua Lai, Weilin Jiang, Guang Chen: USP47 stabilizes BACH1 to promote the Warburg effect and non-small cell lung cancer development via stimulating Hk2 and Gapdh transcription. Am J Cancer Res 2022;12(1):91-107. (Full text, PDF)
Zhiwei Chen, Hyoung Jae Lee, Hangun Kim, Sayeon Cho, Kwonseop Kim: δ-Catenin promotes cell migration and invasion via Bcl-2-regulated suppression of autophagy in prostate cancer cells. Am J Cancer Res 2022;12(1):108-122. (Full text, PDF)
Fu Ou-Yang, Chung-Liang Li, Chia-Chi Chen, Yi-Chun Shen, Sin-Hua Moi, Chi-Wen Luo, Wei-Ya Xia, Ying-Nai Wang, Heng-Huan Lee, Lu-Hai Wang, Shao-Chun Wang, Mei-Ren Pan, Ming-Feng Hou, Mien-Chie Hung: De-glycosylated membrane PD-L1 in tumor tissues as a biomarker for responsiveness to atezolizumab (Tecentriq) in advanced breast cancer patients. Am J Cancer Res 2022;12(1):123-137. (Full text, PDF)
Kelsey E Huntington, Anna Louie, Lanlan Zhou, Attila A Seyhan, Aaron WP Maxwell, Wafik S El-Deiry: Colorectal cancer extracellular acidosis decreases immune cell killing and is partially ameliorated by pH-modulating agents that modify tumor cell cytokine profiles. Am J Cancer Res 2022;12(1):138-151. (Full text, PDF)
Haoyu Wang, Xiaokang Li, Ying Yuan, Yiwei Tong, Siyi Zhu, Renhong Huang, Kunwei Shen, Yi Guo, Yuanyuan Wang, Xiaosong Chen: Association of machine learning ultrasound radiomics and disease outcome in triple negative breast cancer. Am J Cancer Res 2022;12(1):152-164. (Full text, PDF)
Conor H O’Neill, Min Tan, Jun Yan, Yan Li, Robert C G Martin: Perioperative systemic immunophenotype following irreversible electroporation (IRE) predicts recurrence. Am J Cancer Res 2022;12(1):165-175. (Full text, PDF)
Trang Thi-Huynh Le, Chia-Ling Hsieh, I-Hsuan Lin, Cheng-Ying Chu, Anh Duy Do, Seu-Hwa Chen, Katsumi Shigemura, Koichi Kitagawa, Masato Fujisawa, Ming-Che Liu, Kuan-Chou Chen, Shian-Ying Sung: The ADAM9/UBN2/AKR1C3 axis promotes resistance to androgen-deprivation in prostate cancer. Am J Cancer Res 2022;12(1):176-197. (Full text, PDF)
Seungjun Seo, Eun Ho Kim, Won-Seok Chang, Won-Seok Lee, Ki-Hwan Kim, Jong-Ki Kim: Enhanced proton treatment with a LDLR-ligand peptide-conjugated gold nanoparticles targeting the tumor microenvironment in an infiltrative brain tumor model. Am J Cancer Res 2022;12(1):198-209. (Full text, PDF)
Prathyusha Konda, John A Roque III, Liubov M Lifshits, Angelita Alcos, Eissa Azzam, Ge Shi, Colin G Cameron, Sherri A McFarland, Shashi Gujar: Photodynamic therapy of melanoma with new, structurally similar, NIR-absorbing ruthenium (II) complexes promotes tumor growth control via distinct hallmarks of immunogenic cell death. Am J Cancer Res 2022;12(1):210-228. (Full text, PDF)
Yuxin Zhuang, Guang Yang, Shaoyu Wu, Jianjun Chen, Jiayin Guo, Dongling Quan, Tingting Zhang, Zichao Yang, Shaobin Tan, Yuheng Ji, Zhipeng Chen, Lin Lv: 5-arylalkynyl-2-benzoyl thiophene: a novel microtubule inhibitor exhibits antitumor activity without neurological toxicity. Am J Cancer Res 2022;12(1):229-246. (Full text, PDF)
Jingtai Zhi, Jiaoyu Yi, Xiukun Hou, Wei Wang, Weiwei Yang, Linfei Hu, Jianfeng Huang, Shicheng Guo, Xianhui Ruan, Ming Gao, Xiangqian Zheng: Targeting SHP2 sensitizes differentiated thyroid carcinoma to the MEK inhibitor. Am J Cancer Res 2022;12(1):247-264. (Full text, PDF)
Hong-Min Lu, Yu-Jie Fu, Ning Liu, Wu-Yan Xia, Hai-Yan Chen, Meng-Yao Liu, Lin-Feng Li, Jian-Xin Gao: A novel tumor-specific broad-spectral monoclonal antibody to PL2L60 is highly effective for the treatment of various types of cancers from human and mouse. Am J Cancer Res 2022;12(1):265-279. (Full text, PDF)
Marlène Deschuyter, David Yannick Leger, Anne Verboom, Alain Chaunavel, Abderrahman Maftah, Jean-Michel Petit: ST3GAL2 knock-down decreases tumoral character of colorectal cancer cells in vitro and in vivo. Am J Cancer Res 2022;12(1):280-302. (Full text, PDF)
Jian-Xia Xu, Jie-Ni Yu, Xiao-Jie Wang, Yan-Xi Xiong, Yuan-Fei Lu, Jia-Ping Zhou, Qiao-Mei Zhou, Xiao-Yan Yang, Dan Shi, Xiao-Shan Huang, Shu-Feng Fan, Ri-Sheng Yu: A radiologic diagnostic scoring model based on CT features for differentiating gastric schwannoma from gastric gastrointestinal stromal tumors. Am J Cancer Res 2022;12(1):303-314. (Full text, PDF)
Amriti R Lulla, Yan Zhou, Marie D Ralff, Avital Lev, David T Dicker, Wafik S El-Deiry: miR-3132 upregulates surface TRAIL to induce apoptotic cell death in cancer cells. Am J Cancer Res 2022;12(1):315-326. (Full text, PDF)
Jørgen Sikkeland, Matthew Yoke Wui Ng, Hatice Zeynep Nenseth, Bilal Unal, Su Qu, Yang Jin, Anne Simonsen, Fahri Saatcioglu: STAMP2 suppresses autophagy in prostate cancer cells by modulating the integrated stress response pathway. Am J Cancer Res 2022;12(1):327-336. (Full text, PDF)
David J H Shih, Mei-Kuang Chen, Jun Yin, Daniel J McGrail, Hui Dai, Rongbin Wei, Jing Zhang, Wenjin Jim Zheng, Kim-Anh Do, Liuqing Yang, Mien-Chie Hung, Shiaw-Yih Lin: Exploiting induced vulnerability to overcome PARPi resistance and clonal heterogeneity in BRCA mutant triple-negative inflammatory breast cancer. Am J Cancer Res 2022;12(1):337-354. (Full text, PDF)
Alia M Attia, Hanan A Eltybe, Mayada F Sedik, Ahmed Mubarak Hefni, Marwa I Abdelgawad, Ashraf Farrag, Abdelhakeem A Essa, Mohamed M El-Barody, Noha M Attia: The efficacy and safety of extended adjuvant temozolomide following concurrent radio-chemotherapy among Egyptian patients with newly diagnosed glioblastoma multiforme. Am J Cancer Res 2022;12(1):355-370. (Full text, PDF)
Fariborz Asghari Alashti, Bahram Goliaei, Zarrin Minuchehr: Analyzing large scale gene expression data in colorectal cancer reveals important clues; CLCA1 and SELENBP1 downregulated in CRC not in normal and not in adenoma. Am J Cancer Res 2022;12(1):371-380. (Full text, PDF)
Peiqiang Yi, Huan Li, Jun Su, Jialin Cai, Cheng Xu, Jiayi Chen, Lu Cao, Min Li: Trastuzumab aggravates radiation induced cardiotoxicity in mice. Am J Cancer Res 2022;12(1):381-395. (Full text, PDF)
Patricia Castillo, Omonigho Aisagbonhi, Cheryl C Saenz, Wael M ElShamy: Novel insights linking BRCA1-IRIS role in mammary gland development to formation of aggressive PABCs: the case for longer breastfeeding. Am J Cancer Res 2022;12(1):396-426. (Full text, PDF)
Hanying Wang, Xin He, Zheng Li, Hongchuan Jin, Xian Wang, Ling Li: Guanosine primes acute myeloid leukemia for differentiation via guanine nucleotide salvage synthesis. Am J Cancer Res 2022;12(1):427-444. (Full text, PDF, Supplementary Table 1)
Rushikesh Potdar, Benjamin A Gartrell, Robert Given, Lawrence Karsh, Jeffrey Frankel, Karen Nenno, Kris O'MalleyLeFebvre, Amitabha Bhaumik, Sharon McCarthy, Tracy McGowan, Christopher Pieczonka: Concomitant use of oral anticoagulants in patients with advanced prostate cancer receiving apalutamide: A post-hoc analysis of TITAN and SPARTAN studies. Am J Cancer Res 2022;12(1):445-450. (Full text, PDF)
