Ge Gao, Liqiang Wang, Changfeng Li: Circ_0006790 carried by bone marrow mesenchymal stem cell-derived exosomes regulates S100A11 DNA methylation through binding to CBX7 in pancreatic ductal adenocarcinoma. Am J Cancer Res 2022;12(5):1934-1959. (Full text, PDF)
Meng Wei, Ran Yang, Mujie Ye, Yong Zhan, Baihui Liu, Lingdu Meng, Lulu Xie, Min Du, Junfeng Wang, Runnan Gao, Deqian Chen, Rui Dong, Kuiran Dong: MYBL2 accelerates epithelial-mesenchymal transition and hepatoblastoma metastasis via the Smad/SNAI1 pathway. Am J Cancer Res 2022;12(5):1960-1981. (Full text, PDF)
Chaotao Tang, Jun Li, Zhenzhen Yang, Youxiang Chen, Chunyan Zeng: Different lipid metabolic profiles and their associated genes in sessile serrated adenoma or polyps compared to hyperplastic polyps. Am J Cancer Res 2022;12(5):1982-1994. (Full text, PDF)
Huaxiang Wang, Chengkai Yang, Yi Jiang, Huanzhang Hu, Jian Fang, Fang Yang: A novel ferroptosis-related gene signature for clinically predicting recurrence after hepatectomy of hepatocellular carcinoma patients. Am J Cancer Res 2022;12(5):1995-2011. (Full text, PDF)
Lin Li, Kai Lei, Yingcheng Lyu, Binghua Tan, Ruihao Liang, Duoguang Wu, Kefeng Wang, Wenjian Wang, Huayue Lin, Minghui Wang: hsa_circ_0001741 promotes esophageal squamous cell carcinoma stemness, invasion and migration by sponging miR-491-5p to upregulate NOTCH3 expression. Am J Cancer Res 2022;12(5):2012-2031. (Full text, PDF)
Hui Qiu, Muchen Xu, Yan Wang, Xin Wen, Xueting Chen, Wanming Liu, Nie Zhang, Xin Ding, Longzhen Zhang: A novel preoperative MRI-based radiomics nomogram outperforms traditional models for prognostic prediction in pancreatic ductal adenocarcinoma. Am J Cancer Res 2022;12(5):2032-2049. (Full text, PDF)
Jiabin Wang, Qingzhu Qiu, Ningzi Lian, Huagen Wang, Qiaoling Zheng, Yinghong Yang, Yubin Ma, Yajun Zhao, Ping Li, Jianxian Lin, Jun Lu, Qiyue Chen, Longlong Cao, Mi Lin, Changming Huang, Jianwei Xie: An immunosuppressive scoring system to predict recurrence and assist in decision regarding postoperative adjuvant treatment in gastric cancer. Am J Cancer Res 2022;12(5):2050-2067. (Full text, PDF)
Jaena Park, Rebecca L Kamerer, Marina Marjanovic, Janet E Sorrells, Sixian You, Ronit Barkalifa, Kimberly A Selting, Stephen A Boppart: Label-free optical redox ratio from urinary extracellular vesicles as a screening biomarker for bladder cancer. Am J Cancer Res 2022;12(5):2068-2083. (Full text, PDF)
Yi-Ling Chen, Kuo-Ting Lee, Chih-Yang Wang, Che-Hung Shen, Sheau-Chiann Chen, Wei-Pang Chung, Ya-Ting Hsu, Yao-Lung Kuo, Pai-Sheng Chen, Chun Hei Antonio Cheung, Chih-Peng Chang, Meng-Ru Shen, Hui-Ping Hsu: Low expression of cytosolic NOTCH1 predicts poor prognosis of breast cancer patients. Am J Cancer Res 2022;12(5):2084-2101. (Full text, PDF)
Taylor E Arnoff, Wafik S El-Deiry: MDM2/MDM4 amplification and CDKN2A deletion in metastatic melanoma and glioblastoma multiforme may have implications for targeted therapeutics and immunotherapy. Am J Cancer Res 2022;12(5):2102-2117. (Full text, PDF)
Venkateshwar Madka, Arielle De La Cruz, Gopal Pathuri, Janani Panneerselvam, Yuting Zhang, Nicole Stratton, Sean Hacking, Niklas K Finnberg, Howard P Safran, Shizuko Sei, Elizabeth R Glaze, Robert Shoemaker, Jennifer T Fox, Alexander G Raufi, Wafik S El-Deiry, Chinthalapally V Rao: Oral administration of TRAIL-inducing small molecule ONC201/TIC10 prevents intestinal polyposis in the Apcmin/+ mouse model. Am J Cancer Res 2022;12(5):2118-2131. (Full text, PDF)
Leisheng Zhang, Min Liu, Baoquan Song, Wenjing Miao, Rucai Zhan, Sijun Yang, Zhihai Han, Hui Cai, Xianghong Xu, Yixiao Zhao, Zhongchao Han, Tiankang Guo, Jun Yao, Qing Huang: Decoding the multidimensional signatures of resident and expanded natural killer cells generated from perinatal blood. Am J Cancer Res 2022;12(5):2132-2145. (Full text, PDF)
Hideo Takahashi, Masanori Oshi, Li Yan, Itaru Endo, Kazuaki Takabe: Gastric cancer with enhanced apical junction pathway has increased metastatic potential and worse clinical outcomes. Am J Cancer Res 2022;12(5):2146-2159. (Full text, PDF)
Nanye Wang, Huimin Fan, Shuhua Fu, Shaojun Li, Bin Zhou, Qifang Jin, Zhipeng You: Long noncoding RNA UCA1 promotes carboplatin resistance in retinoblastoma cells by acting as a ceRNA of miR-206. Am J Cancer Res 2022;12(5):2160-2172. (Full text, PDF)
Lin Yang, Travis Vander Steen, Ingrid Espinoza, Elisabet Cuyàs, Sara Verdura, Javier A Menendez, Ruth Lupu: Nuclear moonlighting of the secreted growth factor heregulin drives endocrine-resistant breast cancer independently of HER2/HER3 signaling. Am J Cancer Res 2022;12(5):2173-2188. (Full text, PDF)
Yung-Yeh Su, Yu-Lin Ting, Chih-Jung Wang, Ying-Jui Chao, Ting-Kai Liao, Ping-Jui Su, Nai-Jung Chiang, I-Chuang Liao, Yu-Ting Yu, Yi-Sheng Liu, Hong-Ming Tsai, Yi-Jie Li, Chien-Jui Huang, I-Ting Liu, Hui-Jen Tsai, Chia-Jui Yen, Yan-Shen Shan, Li-Tzong Chen: Improved survival with induction chemotherapy and conversion surgery in locally advanced unresectable pancreatic cancer: a single institution experience. Am J Cancer Res 2022;12(5):2189-2202. (Full text, PDF)
Shuo Wang, Qi Shi, Yuze Zhao, Yuguang Song, Guoliang Qiao, Guangjie Liu, Qian Zhu, Lefu Huang, Chang Xu, Bing Liu, Zheng Chen, Hongyan Huang: Expansion of CD3+CD8+PD1+ T lymphocytes and TCR repertoire diversity predict clinical responses to adoptive cell therapy in advanced gastric cancer. Am J Cancer Res 2022;12(5):2203-2215. (Full text, PDF)
Lulu Wang, Rongrong Chen, Li Li, Lixia Zhu, Xianbo Huang, Xiujin Ye: Prognostic implication of early minimal residual disease evaluation in patients with chronic myelomonocytic leukemia. Am J Cancer Res 2022;12(5):2216-2225. (Full text, PDF)
Jiongjia Cheng, Xiaofeng Wang, Xuechun Yuan, Guangxiang Liu, Qian Chu: Emerging roles of exosome-derived biomarkers in cancer theranostics: messages from novel protein targets. Am J Cancer Res 2022;12(5):2226-2248. (Full text, PDF)
Joni C Sedillo, Vincent L Cryns: Targeting the methionine addiction of cancer. Am J Cancer Res 2022;12(5):2249-2276. (Full text, PDF)
Yuan Li, Lu Lu, Guangtao Zhang, Guang Ji, Hanchen Xu: The role and therapeutic implication of endoplasmic reticulum stress in inflammatory cancer transformation. Am J Cancer Res 2022;12(5):2277-2292. (Full text, PDF)
Andrew J Massey: Chk1 inhibitor-induced DNA damage increases BFL1 and decreases BIM but does not protect human cancer cell lines from Chk1 inhibitor-induced apoptosis. Am J Cancer Res 2022;12(5):2293-2309. (Full text, PDF)
Shanshan Sun, Jiali Shi, Xin Wang, Changgang Huang, Yuqian Huang, Jiayun Xu, Yuanyuan Jiang, Liying Cao, Tian Xie, Yongjie Wang, Zhihui Huang: Atractylon inhibits the tumorigenesis of glioblastoma through SIRT3 signaling. Am J Cancer Res 2022;12(5):2310-2322. (Full text, PDF)
Xingjie Ma, Weibo Qi, Fan Yang, Huan Pan: Deubiquitinase JOSD1 promotes tumor progression via stabilizing Snail in lung adenocarcinoma. Am J Cancer Res 2022;12(5):2323-2336. (Full text, PDF)
Hongjun Fei, Xiongming Chen: Development of a novel five-gene immune-related risk model for the prognosis evaluation of prostate adenocarcinoma patients. Am J Cancer Res 2022;12(5):2337-2349. (Full text, PDF)
Ock-Hwa Kim, Bo-Yun Choi, Dong Kwan Kim, Na Hyun Kim, Jin Kyung Rho, Woo Jun Sul, Sei Won Lee: The microbiome of lung cancer tissue and its association with pathological and clinical parameters. Am J Cancer Res 2022;12(5):2350-2362. (Full text, PDF)
Zhen Xue, Shuang Zheng, Dongli Linghu, Boning Liu, Yi Yang, Mei-Kuang Chen, Hua Huang, Jiaming Song, Hongyue Li, Jing Wang, Mien-Chie Hung, Diansheng Zhong, Linlin Sun: PD-L1 deficiency sensitizes tumor cells to DNA-PK inhibition and enhances cGAS-STING activation. Am J Cancer Res 2022;12(5):2363-2375. (Full text, PDF)
Ming-Szu Hung, Yu-Ching Lin, Fen-Fen Chen, Yuan-Yuan Jiang, Yu-Hung Fang, Ming-Shian Lu, Chin-Kuo Lin, Tsung-Ming Yang, Jrhau Lung, Chih-Cheng Chen, Kuan-Der Lee, Ying-Huang Tsai: The potential and limitation of targeted chromosomal breakpoint sequencing for the ROS1 fusion gene identification in lung cancer. Am J Cancer Res 2022;12(5):2376-2386. (Full text, PDF, Supplementary Table 3)
Xue Hou, Suxia Lin, Yongdong Liu, Kaicheng Wang, Zicheng Yu, Junhao Jia, Juan Yu, Wei Zheng, Jing Bai, Lianpeng Chang, Jing Chen, Meichen Li, Likun Chen: Analysis of the tumor microenvironment and mutation burden identifies prognostic features in thymic epithelial tumors. Am J Cancer Res 2022;12(5):2387-2396. (Full text, PDF)
Siqi Tang, Keyong Liao, Yongpeng Shi, Tingting Tang, Beibei Cui, Zunnan Huang: Bioinformatics analysis of potential Key lncRNA-miRNA-mRNA molecules as prognostic markers and important ceRNA axes in gastric cancer. Am J Cancer Res 2022;12(5):2397-2418. (Full text, PDF, Supplementary Table 3)
Weisi Liu, Bishoy M Faltas: Loss of function mutations in CDKN1A are permissive for APOBEC3-induced mutagenesis in urothelial carcinoma. Am J Cancer Res 2022;12(5):2419-2421. (Full text, PDF)
