Murad Alahdal, Li Duan, Hongwei Ouyang, Daping Wang: The role of indoleamine 2,3 dioxygenase 1 in the osteoarthritis. Am J Transl Res 2020;12(6):2322-2343. (Full text, PDF)
Zhe Fan, Jingjing Zong, Wan Yee Lau, Yewei Zhang: Indocyanine green and its nanosynthetic particles for the diagnosis and treatment of hepatocellular carcinoma. Am J Transl Res 2020;12(6):2344-2352. (Full text, PDF)
Jing An, Bo Chen, Xin Kang, Rui Zhang, Yunshan Guo, Jingjing Zhao, Hao Yang: Neuroprotective effects of natural compounds on LPS-induced inflammatory responses in microglia. Am J Transl Res 2020;12(6):2353-2378. (Full text, PDF)
Zhi Chen, Wei-Hua Dong, Qi Wu, Jun Wang: Two-layer regulation of TRAF6 mediated by both TLR4/NF-kB signaling and miR-589-5p increases proinflammatory cytokines in the pathology of severe acute pancreatitis. Am J Transl Res 2020;12(6):2379-2395. (Full text, PDF)
Wenchang Zhou, Aoling Cai, Binbin Nie, Wen Zhang, Ting Yang, Ning Zheng, Anne Manyande, Xuxia Wang, Fuqiang Xu, Xuebi Tian, Jie Wang: Investigation of robust visual reaction and functional connectivity in the rat brain induced by rocuronium bromide with functional MRI. Am J Transl Res 2020;12(6):2396-2408. (Full text, PDF)
Qiong Li, Tao Yu, Fang Wang, Xin Liu, Zuolin Wang: Endothelial progenitor cells with stem cells enhance osteogenic efficacy. Am J Transl Res 2020;12(6):2409-2424. (Full text, PDF)
Hua Bai, Peipei Xu, Lili Wang, Bing Chen: A centromere-associated gene score for rapid determination of risk in multiple myeloma. Am J Transl Res 2020;12(6):2425-2438. (Full text, PDF)
Roseane Carvalho Vasconcelos, Camyla Ferreira, Eduarda Medeiros de Araújo, Fabiana Motta, Mauricio Bomio, Raimundo Fernandes de Araújo Júnior, Daniel Felipe Fernandes Paiva, Flavia Q Pirih, Jose Sandro Pereira da Silva, Alan B Chan, Luis J Cruz, Makiko Ishii, Caroline Addison Carvalho Xavier de Medeiros, Gerlane Coelho Bernardo Guerra, Aurigena Antunes de Araújo: Zirconia/hydroxyapatite (80/20) scaffold repair in critical size calvarial defect increased FGF-2, osteocalcin and OPG immunostaining and IL-10 levels. Am J Transl Res 2020;12(6):2439-2450. (Full text, PDF)
Feng Zhang, Qianwen Li, Kai Zhu, Junfeng Zhu, Jiajia Li, Yuan Yuan, Pingping Zhang, Lili Zhou, Lin Liu: LncRNA LINC00265/miR-485-5p/IRF2-mediated autophagy suppresses apoptosis in acute myeloid leukemia cells. Am J Transl Res 2020;12(6):2451-2462. (Full text, PDF)
Mayson H Alkhatib, Majidah A Aljadani, Sawsan H Mahassni: Carrying epirubicin on nanoemulsion containing algae and cinnamon oils augments its apoptotic and anti-invasion effects on human colon cancer cells. Am J Transl Res 2020;12(6):2463-2472. (Full text, PDF)
Yuanxiang Liu, Chengwu Liu, Ruoxuan Huang, Kaidi Chen, Baoxin Huang, Quan Liu, Zhuofan Chen, Zhipeng Li: Effects of fluorinated porcine hydroxyapatite on lateral ridge augmentation: an experimental study in the canine mandible. Am J Transl Res 2020;12(6):2473-2487. (Full text, PDF)
Cho Rong Park, Myung Geun Song, Ji-Yong Park, Hyewon Youn, June-Key Chung, Jae Min Jeong, Yun-Sang Lee, Gi Jeong Cheon, Keon Wook Kang: Conjugation of arginylglycylaspartic acid to human serum albumin decreases the tumor-targeting effect of albumin by hindering its secreted protein acidic and rich in cysteine-mediated accumulation in tumors. Am J Transl Res 2020;12(6):2488-2498. (Full text, PDF)
Xin Yu, Lei Wang, Lin Zou, Mengjie Li, Tiansheng Li, Linlin Hou, Yameng Guo, Danfeng Shen, Guiqin Sun, Di Qu, Xunjia Cheng, Li Chen: Growth inhibition by bacterial Cas2Em proteins expressed in mammalian cells. Am J Transl Res 2020;12(6):2499-2520. (Full text, PDF)
Yung-Che Chen, Kuo-Tung Huang, Mao-Chang Su, Po-Yuan Hsu, Chien-Hung Chin, I-Chun Lin, Chia-Wei Liou, Ting-Ya Wang, Yong-Yong Lin, Chang-Chun Hsiao, Meng-Chih Lin: Aberrant DNA methylation levels of the formyl peptide receptor 1/2/3 genes are associated with obstructive sleep apnea and its clinical phenotypes. Am J Transl Res 2020;12(6):2521-2537. (Full text, PDF)
Zhengjia Liu, Leng Han, Haixiang Yu, Nan Gao, Hua Xin: LINC01619 promotes non-small cell lung cancer development via regulating PAX6 by suppressing microRNA-129-5p. Am J Transl Res 2020;12(6):2538-2553. (Full text, PDF)
Han-Bing Wu, Shi-Si Huang, Chang-Geng Lu, Shao-Dong Tian, Ming Chen: CircAPLP2 regulates the proliferation and metastasis of colorectal cancer by targeting miR-101-3p to activate the Notch signalling pathway. Am J Transl Res 2020;12(6):2554-2569. (Full text, PDF)
Jing Zheng, Min Zeng, Jia-Bin Nian, Lian-Ya Zeng, Zhi Fu, Qiu-Ju Huang, Xin Wei: The CXCR4/miR-125b/FoxP3 axis regulates the function of the epithelial barrier via autophagy in allergic rhinitis. Am J Transl Res 2020;12(6):2570-2584. (Full text, PDF)
Zehuan Li, Zhanghan Chen, Yanling Feng, Guohua Hu, Ying Jiang: CircMMP11 acts as a ce-circRNA in breast cancer progression by regulating miR-1204. Am J Transl Res 2020;12(6):2585-2599. (Full text, PDF)
Ya-Ting Luo, Ying-Fan Liang, Huan He, Meng-Ting Zhang, Rui Wang, Hong-Lin Li: The immunosuppressant fingolimod ameliorates experimental autoimmune myasthenia gravis by regulating T-cell balance and cytokine secretion. Am J Transl Res 2020;12(6):2600-2613. (Full text, PDF)
Peijun Yang, Xuan Zhang, Zhibin Lin, Quancheng Wang, Dongnan Guo, Pengcheng Zhang, Long Yang, Hong Zhang, Rui Ding, Kaishan Tao, Xiao Li, Kefeng Dou: Adoptive transfer of polarized M2c macrophages ameliorates acute rejection in rat liver transplantation. Am J Transl Res 2020;12(6):2614-2626. (Full text, PDF)
Yoon Young Choi, Jin-I Seok, Jong-Ik Hwang, Dong-Sik Kim: Co-administration of everolimus and N-acetylcysteine attenuates hepatic stellate cell activation and hepatic fibrosis. Am J Transl Res 2020;12(6):2627-2639. (Full text, PDF)
Zhenhan Deng, Xueqin Gao, Xuying Sun, Yan Cui, Sarah Amra, Johnny Huard: Gender differences in tibial fractures healing in normal and muscular dystrophic mice. Am J Transl Res 2020;12(6):2640-2651. (Full text, PDF)
Takashi Nagase, Koji Ueno, Takahiro Mizoguchi, Makoto Samura, Takasuke Harada, Kotaro Suehiro, Bungo Shirasawa, Noriyasu Morikage, Kimikazu Hamano: Allogeneic fibroblast sheets accelerate cutaneous wound healing equivalent to autologous fibroblast sheets in mice. Am J Transl Res 2020;12(6):2652-2663. (Full text, PDF)
Jiyuan Xing, Qingmiao Shi, Junjie Zhao, Zujiang Yu: Identifying drug candidates for hepatocellular carcinoma based on differentially expressed genes. Am J Transl Res 2020;12(6):2664-2674. (Full text, PDF, Supplementary Data)
Xinghan Liu, Yujun Xu, Yi Li, Yuchen Pan, Zhiheng Sun, Shuli Zhao, Yayi Hou: Ganoderma lucidum fruiting body extracts inhibit colorectal cancer by inducing apoptosis, autophagy, and G0/G1 phase cell cycle arrest in vitro and in vivo. Am J Transl Res 2020;12(6):2675-2684. (Full text, PDF)
Gang Chen, Jiandong Li, Zhenyu Wang, Wenge Liu: Ezetimibe protects against spinal cord injury by regulating autophagy and apoptosis through inactivation of PI3K/AKT/mTOR signaling. Am J Transl Res 2020;12(6):2685-2694. (Full text, PDF)
Banglv Ju, Zhilan Liu, Chao Nai, Xinyong Zhu: Long non-coding RNA CASC2 induces apoptosis and autophagy in human colon cancer cells via modulation of TRIM16 expression. Am J Transl Res 2020;12(6):2695-2702. (Full text, PDF)
Min Wang, Di Hu, Wen Zeng, Sichao Chen, Yihui Huang, Ling Zhou, Wei Zhou, Wei Wei, Chao Zhang, Zeming Liu, Liang Guo: New proposed tumor-node-metastasis staging system for medullary thyroid carcinoma based on the Surveillance, Epidemiology, and End Results database. Am J Transl Res 2020;12(6):2703-2710. (Full text, PDF)
Yue-Qiu Teng, Hua Jin, Zhi-Yu Liu, Dan-Dan Li, Xiang-Mei Ye, Lu-Yuan Yang, Jin Zhou: The Lyn-SIRT1 signaling pathway is involved in imatinib resistance in chronic myeloid leukaemia. Am J Transl Res 2020;12(6):2711-2725. (Full text, PDF)
Qi Gao, Yanfeng Wang: Long noncoding RNA MALAT1 regulates apoptosis in ischemic stroke by sponging miR-205-3p and modulating PTEN expression. Am J Transl Res 2020;12(6):2738-2748. (Full text, PDF)
Junyu Lu, Qian Li, Zimeng Wu, Zhimei Zhong, Pan Ji, Hongyuan Li, Cuiying He, Jihua Feng, Jianfeng Zhang: Two gene set variation indexes as potential diagnostic tool for sepsis. Am J Transl Res 2020;12(6):2749-2759. (Full text, PDF)
Changlin Zhai, Huilin Hu, Guanmin Tang, Haihua Pan, Yi Zhang, Gang Qian: MicroRNA-101a protects against the H2O2-induced injury on cardiomyocytes via targeting BCL2L11. Am J Transl Res 2020;12(6):2760-2768. (Full text, PDF)
Lina Gong, Pu Yang, Ling Hu, Chen Zhang: MiR-181b suppresses the progression of epilepsy by regulation of lncRNA ZNF883. Am J Transl Res 2020;12(6):2769-2780. (Full text, PDF)
Huiyu Dong, Shengjie Sun, Tao Yan, Chao Liang, Jundong Zhu, Chenkui Miao, Chao Qin, Pengfei Shao, Zengjun Wang, Jie Li, Pu Li: MicroRNA-195 inhibits proliferation and metastasis in renal cell carcinoma via regulating HMGA1. Am J Transl Res 2020;12(6):2781-2792. (Full text, PDF)
Yaqiang Li, Yu Wu, Yiming Zeng, Dongyun Gu: Biomechanical differences before and after arthroscopic partial meniscectomy in patients with semilunar and discoid lateral meniscus injury. Am J Transl Res 2020;12(6):2793-2804. (Full text, PDF)
Ke’Yona T Barton, Dawn R Conklin, Rohit S Ranabhat, Marquis Harper, La’Neesa M Holmes-Cobb, Margarita H Martinez Soto, Jenora T Waterman: Methacholine induced airway contraction in porcine precision cut lung slices from indoor and outdoor reared pigs. Am J Transl Res 2020;12(6):2805-2813. (Full text, PDF)
Lokesh Kumari Kadian, Gulshan Gulshan, Parul Ahuja, Geetanjali Singhal, Shivkant Sharma, Smiti Nanda, Ritu Yadav: Aberrant promoter methylation of NOTCH1 and NOTCH3 and its association with cervical cancer risk factors in North Indian population. Am J Transl Res 2020;12(6):2814-2826. (Full text, PDF)
Yue Li, Ning Li, Jinchun Liu, Xiuqin An: Gr-1highLy6G+Myeloid-derived suppressor cells and their role in a murine model of non-alcoholic steatohepatitis. Am J Transl Res 2020;12(6):2827-2842. (Full text, PDF)
Daiqiang Liu, Xinfeng Chen, Yujie Huang, Shuang Zhang, Jiayi Wu, Jiayan Li, Dan Wang, Bo Tian, Wei Mei: Acute continuous nocturnal light exposure decreases BSR under sevoflurane anesthesia in C57BL/6J mice: possible role of differentially spared light-sensitive pathways under anesthesia. Am J Transl Res 2020;12(6):2843-2859. (Full text, PDF)
Ke Yi, Minmin Hou, Jialing Yuan, Lingyun Yang, Xi Zeng, Mingrong Xi, Jie Chen: LncRNA PVT1 epigenetically stabilizes and post-transcriptionally regulates FOXM1 by acting as a microRNA sponge and thus promotes malignant behaviors of ovarian cancer cells. Am J Transl Res 2020;12(6):2860-2874. (Full text, PDF)
Jun Li, Jian-Yong Zhuo, Wei Zhou, Jia-Wei Hong, Rong-Gao Chen, Hai-Yang Xie, Lin Zhou, Shu-Sen Zheng, Dong-Hai Jiang: Endoplasmic reticulum stress triggers delanzomib-induced apoptosis in HCC cells through the PERK/eIF2α/ATF4/CHOP pathway. Am J Transl Res 2020;12(6):2875-2889. (Full text, PDF)
Gaohua Wu, Fangfang Fan, Pibo Hu, Chao Wang: AGO1 enhances the proliferation and invasion of cholangiocarcinoma via the EMT-associated TGF-β signaling pathway. Am J Transl Res 2020;12(6):2890-2902. (Full text, PDF)
Aijuan He, Anqi Ye, Nan Song, Ninghua Liu, Guangdong Zhou, Yanqun Liu, Xinhai Ye: Phenotypic redifferentiation of dedifferentiated microtia chondrocytes through a three-dimensional chondrogenic culture system. Am J Transl Res 2020;12(6):2903-2915. (Full text, PDF)
Huajian Peng, Xiang Tan, Yongyong Wang, Lei Dai, Guanbiao Liang, Jianji Guo, Mingwu Chen: Clinical significance of Ki67 and circulating tumor cells with an epithelial-mesenchymal transition phenotype in non-small cell lung cancer. Am J Transl Res 2020;12(6):2916-2928. (Full text, PDF)
Leyi Cai, Linzhen Xie, Qirong Dong: Crocin enhances the viability of random pattern skin flaps: involvement of enhancing angiogenesis and inhibiting oxidative stress. Am J Transl Res 2020;12(6):2929-2938. (Full text, PDF)
Tao Yang, Shisheng Li, Jiajia Liu, Danhui Yin, Xinming Yang, Qinglai Tang, Shuhui Wang: Long non-coding RNA KRT16P2/miR-1294/EGFR axis regulates laryngeal squamous cell carcinoma cell aggressiveness. Am J Transl Res 2020;12(6):2939-2955. (Full text, PDF)
Zhiqiang Zhao, Mansi Wu, Xuelin Zhang, Qinglin Jin, Yongqian Wang, Changye Zou, Gang Huang, Junqiang Yin, Xianbiao Xie, Jingnan Shen: CB-5083, an inhibitor of P97, suppresses osteosarcoma growth and stem cell properties by altering protein homeostasis. Am J Transl Res 2020;12(6):2956-2967. (Full text, PDF)
Weili Wang, Zhaoyuan Zhang, Xingyi Kuang, Dan Ma, Jie Xiong, Tingting Lu, Yaming Zhang, Kunling Yu, Siyu Zhang, Jishi Wang, Qin Fang: 4SC-202 induces apoptosis in myelodysplastic syndromes and the underlying mechanism. Am J Transl Res 2020;12(6):2968-2983. (Full text, PDF)
Tianxing Dai, Mingbin Deng, Linsen Ye, Rongqiang Liu, Guozhen Lin, Xiaolong Chen, Hua Li, Wei Liu, Yang Yang, Guihua Chen, Guoying Wang: Prognostic value of combined preoperative gamma-glutamyl transpeptidase to platelet ratio and fibrinogen in patients with HBV-related hepatocellular carcinoma after hepatectomy. Am J Transl Res 2020;12(6):2984-2997. (Full text, PDF)
Ilaria Campesi, Luigi Milella, Mario Palermo, Giovanni Sotgiu, Giorgio Reggiardo, Flavia Franconi: Cigarette smoking affects the differences between male and female phenotypes. Am J Transl Res 2020;12(6):2998-3010. (Full text, PDF)
Qian Chen, Ying Ni, Mi Han, Wen-Jie Zhou, Xiao-Bin Zhu, Ai-Jun Zhang: Integrin-linked kinase improves uterine receptivity formation by activating Wnt/β-catenin signaling and up-regulating MMP-3/9 expression. Am J Transl Res 2020;12(6):3011-3022. (Full text, PDF)
Lingguo Kong, Adheesh Bhandari, Xiaohua Zhang, Ouchen Wang: Proto-oncogene RTL4 promotes tumorigenesis and invasiveness of papillary thyroid cancer. Am J Transl Res 2020;12(6):3023-3032. (Full text, PDF)
Eiji Kashiwagi, Tatsuro Abe, Fumio Kinoshita, Miho Ushijima, Hiroyuki Masaoka, Masaki Shiota, George J Netto, Masatoshi Eto, Hiroshi Miyamoto: The role of adipocytokines and their receptors in bladder cancer: expression of adiponectin or leptin is an independent prognosticator. Am J Transl Res 2020;12(6):3033-3045. (Full text, PDF)
Jingjing Zhao, He Zuo, Ke Ding, Xiuqing Zhang, Ziran Bi, Huaidong Cheng: Changes in plasma IL-1β, TNF-α and IL-4 levels are involved in chemotherapy-related cognitive impairment in early-stage breast cancer patients. Am J Transl Res 2020;12(6):3046-3056. (Full text, PDF)
Yili Zhou, Yili Chi, Adheesh Bhandari, Erjie Xia, Prabhat Chandra Thakur, Jinmiao Qu, Ouchen Wang, Xiaohua Zhang: Downregulated CDH3 decreases proliferation, migration, and invasion in thyroid cancer. Am J Transl Res 2020;12(6):3057-3067. (Full text, PDF)
Xueqin Li, Lei Gao, Linjing Zheng, Jing Shi, Junli Ma: BMP4-mediated autophagy is involved in the metastasis of hepatocellular carcinoma via JNK/Beclin1 signaling. Am J Transl Res 2020;12(6):3068-3077. (Full text, PDF)
Dianying Zhang, Kai Yu, Jie Yang, Shangding Xie, Jian Yang, Li Tan: Senolytic controls bone marrow mesenchymal stem cells fate improving bone formation. Am J Transl Res 2020;12(6):3078-3088. (Full text, PDF)
