Murali Munisamy, Nayonika Mukherjee, Levin Thomas, Amy Trinh Pham, Arash Shakeri, Yusheng Zhao, Jill Kolesar, Praveen P N Rao, Vivek M Rangnekar, Mahadev Rao: Therapeutic opportunities in cancer therapy: targeting the p53-MDM2/MDMX interactions. Am J Cancer Res 2021;11(12):5762-5781. (Full text, PDF)
Faiza Naz, Mengran Shi, Salvia Sajid, Zhao Yang, Changyuan Yu: Cancer stem cells: a major culprit of intra-tumor heterogeneity. Am J Cancer Res 2021;11(12):5782-5811. (Full text, PDF)
Chen Fu, Ziting Yang, Jiankun Yu, Minjie Wei: The interaction between gut microbiome and anti-tumor drug therapy. Am J Cancer Res 2021;11(12):5812-5832. (Full text, PDF)
Qinyi Wang, Junmin Wang, Hongjiao Xiang, Peilun Ding, Tao Wu, Guang Ji: The biochemical and clinical implications of phosphatase and tensin homolog deleted on chromosome ten in different cancers. Am J Cancer Res 2021;11(12):5833-5855. (Full text, PDF)
Lin-Lin Sun, Dong-Li Linghu, Mien-Chie Hung: Ferroptosis: a promising target for cancer immunotherapy. Am J Cancer Res 2021;11(12):5856-5863. (Full text, PDF)
Jin Wu, Guanting Lu, Xinjiang Wang: MDM4 alternative splicing and implication in MDM4 targeted cancer therapies. Am J Cancer Res 2021;11(12):5864-5880. (Full text, PDF)
Bhuvanesh Sukhlal Kalal, Prashant Kumar Modi, Mohd Altaf Najar, Santosh Kumar Behera, Dinesh Upadhya, Thottethodi Subrahmanya Keshava Prasad, Vinitha Ramanath Pai: Hyperphosphorylation of HDAC2 promotes drug resistance in a novel dual drug resistant mouse melanoma cell line model: an in vitro study. Am J Cancer Res 2021;11(12):5881-5901. (Full text, PDF)
Jianqiang Du, Haifeng Sun, Yuying Sun, Jianfei Du, Wangnan Cao, Shengzhi Sun: Assessment of age, period, and cohort effects of lung cancer incidence in Hong Kong and projection up to 2030 based on changing demographics. Am J Cancer Res 2021;11(12):5902-5916. (Full text, PDF)
Yiming Yang, Andrew J Sanders, Fiona Ruge, Xuefei Dong, Yuxin Cui, Qing Ping Dou, Shuqin Jia, Chunyi Hao, Jiafu Ji, Wen G Jiang: Activated leukocyte cell adhesion molecule (ALCAM)/CD166 in pancreatic cancer, a pivotal link to clinical outcome and vascular embolism. Am J Cancer Res 2021;11(12):5917-5932. (Full text, PDF)
Francesca Giordano, Francesca Ida Montalto, Maria Luisa Panno, Sebastiano Andò, Francesca De Amicis: A Notch inhibitor plus Resveratrol induced blockade of autophagy drives glioblastoma cell death by promoting a switch to apoptosis. Am J Cancer Res 2021;11(12):5933-5950. (Full text, PDF)
Nancy Santos-Martínez, Lorenza Díaz, Victor M Ortiz-Ortega, David Ordaz-Rosado, Heriberto Prado-Garcia, Euclides Avila, Fernando Larrea, Rocío García-Becerra: Calcitriol induces estrogen receptor α expression through direct transcriptional regulation and epigenetic modifications in estrogen receptor-negative breast cancer cells. Am J Cancer Res 2021;11(12):5951-5964. (Full text, PDF)
Joanna Szarkowska, Pawel Cwiek, Michal Szymanski, Natalia Rusetska, Iga Jancewicz, Malgorzata Stachowiak, Monika Swiatek, Maciej Luba, Ryszard Konopinski, Szymon Kubala, Renata Zub, Jakub Kucharz, Pawel Wiechno, Janusz A Siedlecki, Sergiusz Markowicz, Elzbieta Sarnowska, Tomasz J Sarnowski: RRM2 gene expression depends on BAF180 subunit of SWISNF chromatin remodeling complex and correlates with abundance of tumor infiltrating lymphocytes in ccRCC. Am J Cancer Res 2021;11(12):5965-5978. (Full text, PDF)
Hongjun Fei, Xiongming Chen: Establishment and validation of an autophagy-related prognostic signature for survival predicting in cutaneous melanoma. Am J Cancer Res 2021;11(12):5979-5991. (Full text, PDF)
Silu Wang, Linyong Du, Hao Chen, Xing Zhang, Bicheng Chen, Lihong Yang: Paracrine production of IL-6 promotes a hypercoagulable state in pancreatic cancer. Am J Cancer Res 2021;11(12):5992-6003. (Full text, PDF)
Heung Man Lee, Shao Chin Lee, Lan He, Alice Pik Shan Kong, Dandan Mao, Yong Hou, Arthur Chi Kong Chung, Gang Xu, Ronald Ching Wan Ma, Juliana Chung Ngor Chan: Legacy effect of high glucose on promoting survival of HCT116 colorectal cancer cells by reducing endoplasmic reticulum stress response. Am J Cancer Res 2021;11(12):6004-6023. (Full text, PDF)
Marcin Michalak, Michał S Lach, Sylwia Borska, Błażej Nowakowski, Kazuo Umezawa, Wiktoria M Suchorska: DHMEQ enhances the cytotoxic effect of cisplatin and carboplatin in ovarian cancer cell lines. Am J Cancer Res 2021;11(12):6024-6041. (Full text, PDF)
Yüksel Filik, Karin Bauer, Emir Hadzijusufovic, Patrick Haider, Georg Greiner, Nadine Witzeneder, Gregor Hoermann, Philipp J Hohensinner, Karoline V Gleixner, Johann Wojta, Wolfgang R Sperr, Peter Valent: PI3-kinase inhibition as a strategy to suppress the leukemic stem cell niche in Ph+ chronic myeloid leukemia. Am J Cancer Res 2021;11(12):6042-6059. (Full text, PDF)
Manabu Futamura, Yoshihisa Tokumaru, Kazuaki Takabe, Hirofumi Arakawa, Yoshimi Asano, Ryutaro Mori, Junichi Mase, Akira Nakakami, Kazuhiro Yoshida: MIEAP, a p53-downstream gene, is associated with suppression of breast cancer cell proliferation and better survival. Am J Cancer Res 2021;11(12):6060-6073. (Full text, PDF)
Chuan Zhang, Zhulu Chen, Chunhua Mo, Diansha Gao, Yuxi Zhu, Shu Qin, Zhong Zuo: Real-world cardiovascular toxicity of immune checkpoint inhibitors in cancer patients: a retrospective controlled cohort study. Am J Cancer Res 2021;11(12):6074-6085. (Full text, PDF)
Leya Groysman, Lindsey Carlsen, Kelsey E Huntington, Wen H Shen, Lanlan Zhou, Wafik S El-Deiry: Chemotherapy-induced cytokines and prognostic gene signatures vary across breast and colorectal cancer. Am J Cancer Res 2021;11(12):6086-6106. (Full text, PDF)
Miao Xue, Yanqin Wu, Bowen Zhu, Xinhua Zou, Wenzhe Fan, Jiaping Li: Advanced hepatocellular carcinoma treated by transcatheter arterial chemoembolization with drug-eluting beads plus lenvatinib versus sorafenib, a propensity score matching retrospective study. Am J Cancer Res 2021;11(12):6107-6118. (Full text, PDF)
Zhixun Zhao, Xiaochen Zhang, Zhongwu Li, Yibo Gao, Xu Guan, Zheng Jiang, Zheng Liu, Ming Yang, Haipeng Chen, Xiaolong Ma, Runkun Yang, Zhao Lu, Hengchang Liu, Lujing Yang, Aiwen Wu, Shuangmei Zou, Xishan Wang: Automated assessment of DNA ploidy, chromatin organization, and stroma fraction to predict prognosis and adjuvant therapy response in patients with stage II colorectal carcinoma. Am J Cancer Res 2021;11(12):6119-6132. (Full text, PDF)
Shuhei Komatsu, Taisuke Imamura, Jun Kiuchi, Yusuke Takashima, Hajime Kamiya, Takuma Ohashi, Hirotaka Konishi, Atsushi Shiozaki, Takeshi Kubota, Kazuma Okamoto, Eigo Otsuji: Depletion of tumor suppressor miRNA-148a in plasma relates to tumor progression and poor outcomes in gastric cancer. Am J Cancer Res 2021;11(12):6133-6146. (Full text, PDF, Table S1)
Javeria Zaheer, A Ram Yu, Hyeongi Kim, Hyun Ji Kang, Min Kyoung Kang, Jae Jun Lee, Jin Su Kim: Diacerein, an inhibitor of IL-1β downstream mediated apoptosis, improves radioimmunotherapy in a mouse model of Burkitt’s lymphoma. Am J Cancer Res 2021;11(12):6147-6159. (Full text, PDF)
Chia-Te Yen, Wen-Jui Wu, Yen-Ting Chen, Wei-Chin Chang, Sheng-Hsiung Yang, Sheng-Yeh Shen, Jian Su, Hsuan-Yu Chen: Surgical resection of brain metastases prolongs overall survival in non-small-cell lung cancer. Am J Cancer Res 2021;11(12):6160-6172. (Full text, PDF)
Wei-Fan Hsu, Hung-Wei Wang, Cheng-Kuo Chen, Hsueh-Chou Lai, Po-Heng Chuang, Ming-Hung Tsai, Wen-Pang Su, Hung-Yao Chen, Chia-Sheng Chu, Jen-Wei Chou, Sheng-Hung Chen, Tsung-Yu Tsai, Wang-De Hsiao, Chun-Che Lin, Guan-Tarn Huang, Jaw-Town Lin, Cheng-Yuan Peng: Alpha-fetoprotein response predicts treatment outcomes in patients with unresectable hepatocellular carcinoma receiving immune checkpoint inhibitors with or without tyrosine kinase inhibitors or locoregional therapies. Am J Cancer Res 2021;11(12):6173-6187. (Full text, PDF)
Jing Yu, Jiayi Wu, Ou Huang, Jianrong He, Li Zhu, Weiguo Chen, Yafen Li, Xiaosong Chen, Kunwei Shen: Distribution and influence of the 21-gene recurrence score on chemotherapy decision-making in special type of breast cancer. Am J Cancer Res 2021;11(12):6188-6199. (Full text, PDF)
Charles R Rogers, Roger Figueroa, Ellen Brooks, Ethan M Petersen, Carson D Kennedy, Darrell M Gray II, Michael Sapienza, Man Hung: Factors associated with colorectal cancer screening intent and uptake among adult Non-Hispanic Black men. Am J Cancer Res 2021;11(12):6200-6213. (Full text, PDF)
Omar Alhalabi, Pavlos Msaouel: Truncating CDKN1A mutations: an insight into the biology of urinary tract carcinomas? Am J Cancer Res 2021;11(12):6214-6217. (Full text, PDF)
Retraction: MicroRNA-187 exerts tumor-suppressing functions in osteosarcoma by targeting ZEB2. Am J Cancer Res 2021;11(12):6218. (Full text, PDF)
