Yichi Zhang, Elizabeth Holland, Anna Dinh, Duc Au, Lichun Sun: Bombesin-drug conjugates in targeted therapy for small cell lung cancer. Am J Cancer Res 2022;12(3):927-937. (Full text, PDF)
Ying Jin, Soek Sin Teh, Harrison Lik Nang Lau, Jianbo Xiao, Siau Hui Mah: Retinoids as anti-cancer agents and their mechanisms of action. Am J Cancer Res 2022;12(3):938-960. (Full text, PDF)
Qian Bai, Zhenjie Pan, Ghulam Nabi, Farooq Rashid, Yang Liu, Suliman Khan: Emerging role of competing endogenous RNA and associated noncoding RNAs in thyroid cancer. Am J Cancer Res 2022;12(3):961-973. (Full text, PDF)
Santhi Latha Pandrangi, Prasanthi Chittineedi, Rajasekhar Chikati, Joji Reddy Lingareddy, Meeravali Nagoor, Suresh Kumar Ponnada: Role of dietary iron revisited: in metabolism, ferroptosis and pathophysiology of cancer. Am J Cancer Res 2022;12(3):974-985. (Full text, PDF)
Muhammad Usman, Mohammad K Okla, Hafiz Muhammad Asif, Gehad AbdElgayed, Fatima Muccee, Shakira Ghazanfar, Mukhtiar Ahmad, Muhammad Junaid Iqbal, Aamina Murad Sahar, Ghania Khaliq, Rabbia Shoaib, Hira Zaheer, Yasir Hameed: A pan-cancer analysis of GINS complex subunit 4 to identify its potential role as a biomarker in multiple human cancers. Am J Cancer Res 2022;12(3):986-1008. (Full text, PDF)
Fen Zhang, Jiecheng Ye, Wenjing Guo, Fenfen Zhang, Liyuan Wang, Anjia Han: TYMS-TM4SF4 axis promotes the progression of colorectal cancer by EMT and upregulating stem cell marker. Am J Cancer Res 2022;12(3):1009-1026. (Full text, PDF)
Ruyu Fan, Shipeng He, Yongqing Wang, Jiaming Qiao, Hongcheng Liu, Levon Galstyan, Arman Ghazaryan, Hui Cai, Shini Feng, Pinyue Ni, Guoqiang Dong, Huafei Li: Targeted delivery of a PROTAC induced PDEδ degrader by a biomimetic drug delivery system for enhanced cytotoxicity against pancreatic cancer cells. Am J Cancer Res 2022;12(3):1027-1041. (Full text, PDF)
Ming Hung Lin, Atikul Islam, Yen-Hui Liu, Chia-Wei Weng, Jun-Han Zhan, Ru-Hao Liang, Alexander S Tikhomirov, Andrey E Shchekotikhin, Pin Ju Chueh: Antibiotic heliomycin and its water-soluble 4-aminomethylated derivative provoke cell death in T24 bladder cancer cells by targeting sirtuin 1 (SIRT1). Am J Cancer Res 2022;12(3):1042-1055. (Full text, PDF)
Bi-Cong Yan, Feng-Hua Ma, Ying Li, Yan-Feng Fan, Zhi-Long Huang, Xiao-Liang Ma, Xue-Ting Wen, Jin-Wei Qiang: An MRI radiomics nomogram improves the accuracy in identifying eligible candidates for fertility-preserving treatment in endometrioid adenocarcinoma. Am J Cancer Res 2022;12(3):1056-1068. (Full text, PDF)
Qian Wu, Yi-Fei Xuan, Ai-Ling Su, Xu-Bin Bao, Ze-Hong Miao, Ying-Qing Wang: TNKS inhibitors potentiate proliferative inhibition of BET inhibitors via reducing β-Catenin in colorectal cancer cells. Am J Cancer Res 2022;12(3):1069-1087. (Full text, PDF)
Yin-Chen Hsu, Sin-Ming Huang, Li-Chun Chang, Yan-Ming Chen, Ya-Hsuan Chang, Jing-Wei Lin, Chien-Chia Lin, Ching-Wen Chen, Hsuan-Yu Chen, Han-Mo Chiu, Sung-Liang Yu: Screening of early-staged colorectal neoplasia by clonal hematopoiesis-based liquid biopsy and machine-learning. Am J Cancer Res 2022;12(3):1088-1101. (Full text, PDF)
Shengjian Huang, Yang Liu, Zhihong Chen, Michael Wang, Vivian C Jiang: PIK-75 overcomes venetoclax resistance via blocking PI3K-AKT signaling and MCL-1 expression in mantle cell lymphoma. Am J Cancer Res 2022;12(3):1102-1115. (Full text, PDF)
Elodie Jouberton, Aurélien Voissiere, Frédérique Penault-Llorca, Florent Cachin, Elisabeth Miot-Noirault: Multicellular tumor spheroids of LNCaP-Luc prostate cancer cells as in vitro screening models for cytotoxic drugs. Am J Cancer Res 2022;12(3):1116-1128. (Full text, PDF)
Chiami Moyama, Mitsugu Fujita, Shota Ando, Keiko Taniguchi, Hiromi Ii, Seisuke Tanigawa, Naoya Hashimoto, Susumu Nakata: Stat5b inhibition blocks proliferation and tumorigenicity of glioblastoma stem cells derived from a de novo murine brain cancer model. Am J Cancer Res 2022;12(3):1129-1142. (Full text, PDF)
Jing Wei, Song Xia, Aiqin Sun, Yaping Qu, Jinyi Gao, Genbao Shao, Wannian Yang, Qiong Lin: Geranylgeranylation signaling promotes breast cancer cell mitosis via the YAP-activated transcription of kinetochore/centromere genes. Am J Cancer Res 2022;12(3):1143-1155. (Full text, PDF)
Alia M Attia, Ashraf Farrag, Noha M Attia, Lamiaa MR Khalaf, Hesham M Hassan, Mahmoud Gamal Ameen, Ebrahim Aboeleuon, Sanaa Saber Abd El-Raheem, Ahmed Mahran, Ahmed Mubarak Hefni: Signet ring cell component predicts the response to neoadjuvant chemoradiotherapy in rectal cancer. Long interim results of a single institution experience. Am J Cancer Res 2022;12(3):1156-1168. (Full text, PDF)
Xin Zhang, Xuan Wang, Wenxing Li, Chengxue Dang, Dongmei Diao: Effectiveness of managing suspected metastasis using plasma D-dimer testing in gastric cancer patients. Am J Cancer Res 2022;12(3):1169-1178. (Full text, PDF)
Zongdong Yu, Hong Li, Jie Zhu, Haibiao Wang, Xiaofeng Jin: The roles of E3 ligases in Hepatocellular carcinoma. Am J Cancer Res 2022;12(3):1179-1214. (Full text, PDF)
Zishao Zhong, Bingjie Zhan, Baohui Xu, Hengjun Gao: Emphasizing the importance of successful eradication of Helicobacter pylori on initial treatment. Am J Cancer Res 2022;12(3):1215-1221. (Full text, PDF)
Derui Yan, Shang Cai, Lu Bai, Zixuan Du, Huijun Li, Peng Sun, Jianping Cao, Nengjun Yi, Song-Bai Liu, Zaixiang Tang: Integration of immune and hypoxia gene signatures improves the prediction of radiosensitivity in breast cancer. Am J Cancer Res 2022;12(3):1222-1240. (Full text, PDF)
Young Min Chung, Wen Bin Tsai, Pragya P Khan, Jessica Ma, Jonathan S Berek, James W Larrick, Mickey C-T Hu: FOXO3-dependent suppression of PD-L1 promotes anticancer immune responses via activation of natural killer cells. Am J Cancer Res 2022;12(3):1241-1263. (Full text, PDF)
Ming Yang, Shi Chang Liu, Ding Jun Hao, Liang Yan, Zhong Kai Liu, Xin Hua Yin: RP11-867G2.8 promotes EMT and chordoma malignant phenotypes by enhancing FUT4 mRNA stability and translation. Am J Cancer Res 2022;12(3):1264-1281. (Full text, PDF, Supplementary Tables 1, 2)
Ivette J Suárez-Arroyo, Ariana Acevedo-Díaz, Tiffany J Ríos-Fuller, Gabriela Ortiz-Soto, Ricardo Vallejo-Calzada, Jael Reyes-Chea, Gerónimo Maldonado-Martínez, Robert J Schneider, Michelle M Martínez-Montemayor: Ganoderma lucidum enhances carboplatin chemotherapy effect by inhibiting the DNA damage response pathway and stemness. Am J Cancer Res 2022;12(3):1282-1294. (Full text, PDF)
Hyesung Kim, Jae Kyung Myung, Seung Sam Paik, Hyunsung Kim, Hosub Park, Yeon Ju Kim, Seung Bum Lee, Heung Up Kim, Hyun Joo Song, In Ho Jeong, Suji Hong, Chul Min Park, Cheol Lee, Younghoon Kim, Bogun Jang: EPHB2 expression is associated with intestinal phenotype of gastric cancer and indicates better prognosis by suppressing gastric cancer migration. Am J Cancer Res 2022;12(3):1295-1308. (Full text, PDF)
Cara Dauch, Sharon Shim, Matthew Wyatt Cole, Nijole C Pollock, Abigail J Beer, Johnny Ramroop, Victoria Klee, Dawn C Allain, Reena Shakya, Sue E Knoblaugh, Jesse Kulewsky, Amanda Ewart Toland: KMT2D loss drives aggressive tumor phenotypes in cutaneous squamous cell carcinoma. Am J Cancer Res 2022;12(3):1309-1322. (Full text, PDF)
Qing Kay Li, Tung-Shing Mamie Lih, Yuefan Wang, Yingwei Hu, Naseruddin Höti, Daniel W Chan, Hui Zhang: Improving the detection of aggressive prostate cancer using immunohistochemical staining of protein marker panels. Am J Cancer Res 2022;12(3):1323-1336. (Full text, PDF)
Gracjana Krzysiek-Maczka, Aneta Targosz, Tomasz Wrobel, Milena Paw, Urszula Szczyrk, Janusz Opila, Malgorzata Strzalka, Mateusz Wierdak, Piotr Major, Tomasz Brzozowski, Jaros?: Time-extended exposure of gastric epithelial cells to secretome of Helicobacter pylori-activated fibroblasts induces reprogramming of gastric epithelium towards pre-cancerogenic and pro-invasive phenotype. Am J Cancer Res 2022;12(3):1337-1371. (Full text, PDF)
Zheng Xu, Jun Shao, Cihua Zheng, Jing Cai, Bowen Li, Xiaogang Peng, Leifeng Chen, Tiande Liu: The E3 ubiquitin ligase RBCK1 promotes the invasion and metastasis of hepatocellular carcinoma by destroying the PPARγ/PGC1α complex. Am J Cancer Res 2022;12(3):1372-1392. (Full text, PDF)
Tae Won Kim, Dae Hee Pyo, Eunbyeol Ko, Nak Hyeon Yun, Su Jeong Song, Soo Min Choi, Hye Kyung Hong, Seok-Hyung Kim, Yoon-La Choi, Jeeyun Lee, Woo Yong Lee, Yong Beom Cho: Expression of SLC22A18 regulates oxaliplatin resistance by modulating the ERK pathway in colorectal cancer. Am J Cancer Res 2022;12(3):1393-1408. (Full text, PDF)
Luyao Zhang, Na Wang, Min Chen, Siran Wu, Jiaoxia Zeng, Fenli Zhou, Qiong Wu, Junye Liu, Yongquan Shi: HDAC6/FOXP3/HNF4α axis promotes bile acids induced gastric intestinal metaplasia. Am J Cancer Res 2022;12(3):1409-1422. (Full text, PDF)
Yunhui Jo, Young In Han, Eunjun Lee, Jaehyeon Seo, Geon Oh, Heehun Sung, Yongha Gi, Hyunwoo Kim, Sangmin Park, Myonggeun Yoon: The combination of tumor treating fields and hyperthermia has synergistic therapeutic effects in glioblastoma cells by downregulating STAT3. Am J Cancer Res 2022;12(3):1423-1432. (Full text, PDF)
Yao-Yin Li, Chuan-Xiang Zhou, Yan Gao: Podoplanin promotes the invasion of oral squamous cell carcinoma in coordination with MT1-MMP and Rho GTPases: Am J Cancer Res. 2015; 5(2): 514-529. Am J Cancer Res 2022;12(3):1433-1434. (Full text, PDF)
Joshua R Huot, Fabrizio Pin, Andrea Bonetto: Muscle weakness caused by cancer and chemotherapy is associated with loss of motor unit connectivity: Am J Cancer Res. 2021; 11(6): 2990-3001. Am J Cancer Res 2022;12(3):1435. (Full text, PDF)
