Zodwa Dlamini, Bonginkosi Shoba, Rodney Hull: Splicing machinery genomics events in acute myeloid leukaemia (AML): in search for therapeutic targets, diagnostic and prognostic biomarkers. Am J Cancer Res 2020;10(9):2690-2704. (Full text, PDF)
Xinrong Lin, Xiaosong Xiang, Liping Hao, Ting Wang, Yongting Lai, Mubalake Abudoureyimu, Hao Zhou, Bing Feng, Xiaoyuan Chu, Rui Wang: The role of Aurora-A in human cancers and future therapeutics. Am J Cancer Res 2020;10(9):2705-2729. (Full text, PDF)
Bagora Bayala, Abdou Azaque Zouré, Théodora M Zohoncon, Bienvenu L Tinguerie, Silvère Baron, Youssef Bakri, Jacques Simpore, Jean-Marc A Lobaccaro: Effects of extracts and molecules derived from medicinal plants of West Africa in the prevention and treatment of gynecological cancers. A Review. Am J Cancer Res 2020;10(9):2730-2741. (Full text, PDF)
Hector Picon, Achuta Kumar Guddati: Mechanisms of resistance in head and neck cancer. Am J Cancer Res 2020;10(9):2742-2751. (Full text, PDF)
Guan-Lian Zou, Xiao-Ran Zhang, Yan-Li Ma, Qing Lu, Ren Zhao, Yong-Zhao Zhu, Yan-Yang Wang: The role of Nrf2/PIWIL2/purine metabolism axis in controlling radiation-induced lung fibrosis. Am J Cancer Res 2020;10(9):2752-2767. (Full text, PDF)
Chenhao Zhou, Jialei Weng, Chunxiao Liu, Qiang Zhou, Wanyong Chen, Jennifer L Hsu, Jialei Sun, Manar Atyah, Yang Xu, Yi Shi, Yinghao Shen, Qiongzhu Dong, Mien-Chie Hung, Ning Ren: High RPS3A expression correlates with low tumor immune cell infiltration and unfavorable prognosis in hepatocellular carcinoma patients. Am J Cancer Res 2020;10(9):2768-2784. (Full text, PDF)
Tiantian Han, Jinyi Gao, Lincui Wang, Yaping Qu, Aiqin Sun, Ke Peng, Jun Zhu, Hanqing Liu, Wannian Yang, Genbao Shao, Qiong Lin: ASK1 inhibits proliferation and migration of lung cancer cells via inactivating TAZ. Am J Cancer Res 2020;10(9):2785-2799. (Full text, PDF)
Rui Zhang, Cuicui Lyu, Wenyi Lu, Yedi Pu, Yanyu Jiang, Qi Deng: Synergistic effect of programmed death-1 inhibitor and programmed death-1 ligand-1 inhibitor combined with chemotherapeutic drugs on DLBCL cell lines in vitro and in vivo. Am J Cancer Res 2020;10(9):2800-2812. (Full text, PDF)
Hua-Dong Chen, Ne Guo, Shan-Shan Song, Chuan-Huizi Chen, Ze-Hong Miao, Jin-Xue He: Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors. Am J Cancer Res 2020;10(9):2813-2831. (Full text, PDF)
Xuefeng Gu, Guoqing Wan, Yue Yang, Yihao Liu, Xintong Yang, Yanjun Zheng, Liying Jiang, Peng Zhang, Dingsheng Liu, Weiming Zhao, Gang Huang, Changlian Lu: SLFN5 influences proliferation and apoptosis by upregulating PTEN transcription via ZEB1 and inhibits the purine metabolic pathway in breast cancer. Am J Cancer Res 2020;10(9):2832-2850. (Full text, PDF)
Dianyun Ren, Gengdu Qin, Jingyuan Zhao, Yan Sun, Bin Zhang, Dan Li, Bo Wang, Xin Jin, Heshui Wu: Metformin activates the STING/IRF3/IFN-β pathway by inhibiting AKT phosphorylation in pancreatic cancer. Am J Cancer Res 2020;10(9):2851-2864. (Full text, PDF)
Jiawei Chen, Isabella Wai-Yin Cheuk, Man-Ting Siu, Weiqin Yang, Alfred SL Cheng, Vivian Yvonne Shin, Ava Kwong: Human haptoglobin contributes to breast cancer oncogenesis through glycolytic activity modulation. Am J Cancer Res 2020;10(9):2865-2877. (Full text, PDF)
Junyoung Choi, Hee Jin Lee, Shinkyo Yoon, Hyun-Min Ryu, Eunjin Lee, Yujin Jo, Seyoung Seo, Deokhoon Kim, Chang Hoon Lee, Wanlim Kim, Joo Young Ha, Soo-Youl Kim, Gyungyub Gong, Kyung Hae Jung, Sook Ryun Park, Sang-We Kim, Kang-Seo Park, Dae Ho Lee: Blockade of CCL2 expression overcomes intrinsic PD-1/PD-L1 inhibitor-resistance in transglutaminase 2-induced PD-L1 positive triple negative breast cancer. Am J Cancer Res 2020;10(9):2878-2894. (Full text, PDF)
Min-Juan Zhang, Wei Gao, Shuai Liu, Sharie Pui-Kei Siu, Min Yin, Judy Chun-Wai Ng, Velda Ling-Yu Chow, Jimmy Yu-Wai Chan, Thian-Sze Wong: CD38 triggers inflammasome-mediated pyroptotic cell death in head and neck squamous cell carcinoma. Am J Cancer Res 2020;10(9):2895-2908. (Full text, PDF)
Adam Kowalewski, Damian Jaworski, Paulina Antosik, Marta Smolińska, Joanna Ligmanowska, Dariusz Grzanka, Łukasz Szylberg: TRIP13 predicts poor prognosis in clear cell renal cell carcinoma. Am J Cancer Res 2020;10(9):2909-2918. (Full text, PDF)
Ava Kwong, Isabella WY Cheuk, Vivian Yvonne Shin, Cecilia YS Ho, Chun-Hang Au, Dona NY Ho, Elaine YL Wong, Stephanie WY Yu, Jiawei Chen, Karen KL Chan, Hextan YS Ngan, Tsun-Leung Chan, Edmond SK Ma: Somatic mutation profiling in BRCA-negative breast and ovarian cancer patients by multigene panel sequencing. Am J Cancer Res 2020;10(9):2919-2932. (Full text, PDF)
Valentina K Todorova, Ping-Ching Hsu, Jeanne Y Wei, Angel Lopez-Candales, Jim Zhongning Chen, L Joseph Su, Issam Makhoul: Biomarkers of inflammation, hypercoagulability and endothelial injury predict early asymptomatic doxorubicin-induced cardiotoxicity in breast cancer patients. Am J Cancer Res 2020;10(9):2933-2945. (Full text, PDF)
Chao Ren, Zong-Jiong Mai, Ying Jin, Ming-Ming He, Zhi-Qiang Wang, Hui-Yan Luo, Dong-Sheng Zhang, Chen-Yi Wu, Feng Wang, Rui-Hua Xu: Anti-PD-1 antibody SHR-1210 plus apatinib for metastatic colorectal cancer: a prospective, single-arm, open-label, phase II trial. Am J Cancer Res 2020;10(9):2946-2954. (Full text, PDF)
Su Yon Jung, Jeanette C Papp, Eric M Sobel, Matteo Pellegrini, Herbert Yu, Zuo-Feng Zhang: Pro-inflammatory cytokine polymorphisms in ONECUT2 and HNF4A and primary colorectal carcinoma: a post genome-wide gene-lifestyle interaction study. Am J Cancer Res 2020;10(9):2955-2976. (Full text, PDF)
Wei An, Mu-Yun Liu, Jing Zhang, Yue-Ping Cui, Jie Gao, Li-Peng Wang, Ying Chen, Li-Xin Yang, He-Zhong Chen, Hai Jin, Feng Liu, Jie Chen, Zhao-Shen Li, Luo-Wei Wang, Xin-Gang Shi, Chang Sun: Endoscopic submucosal dissection versus esophagectomy for early esophageal squamous cell carcinoma with tumor invasion to different depths. Am J Cancer Res 2020;10(9):2977-2992. (Full text, PDF)
Zhiqian Chen, Hao Xie, Mingming Hu, Tianyi Huang, Yanan Hu, Na Sang, Yinglan Zhao: Recent progress in treatment of hepatocellular carcinoma. Am J Cancer Res 2020;10(9):2993-3036. (Full text, PDF)
Feng Wang, Tian-Shu Liu, Xiang-Lin Yuan, Hui-Yan Luo, Kang-Sheng Gu, Ying Yuan, Yan-Hong Deng, Jian-Ming Xu, Yu-Xian Bai, Ying Wang, Wang-Jun Liao, He-Long Zhang, Feng Bi, Bang-Mao Wang, Zhi-Xiang Zhuang, Teng-Jia Jiang, Rui-Hua Xu: Trastuzumab plus docetaxel and capecitabine as a first-line treatment for HER2-positive advanced gastric or gastroesophageal junction cancer: a phase II, multicenter, open-label, single-arm study. Am J Cancer Res 2020;10(9):3037-3046. (Full text, PDF)
Davendra Sohal, Smitha Krishnamurthi, Rita Tohme, Xiaorong Gu, Daniel Lindner, Terry H Landowski, John Pink, Tomas Radivoyevitch, Sherry Fada, Zhenghong Lee, Dale Shepard, Alok Khorana, Yogen Saunthararajah: A pilot clinical trial of the cytidine deaminase inhibitor tetrahydrouridine combined with decitabine to target DNMT1 in advanced, chemorefractory pancreatic cancer. Am J Cancer Res 2020;10(9):3047-3060. (Full text, PDF)
