Wu Lin, Jiong Qian, Haohao Wang, Ling Ren, Yan Yang, Chuanzhi Chen, Xiangliu Chen, Yingying Huang, Jin Liu, Nong Xu, Lisong Teng: Cisplatin plus anti-PD-1 antibody enhanced treatment efficacy in advanced esophageal squamous cell carcinoma. Am J Cancer Res 2022;12(2):451-468. (Full text, PDF)
Abrar I Aljohani, Michael S Toss, Khloud A El-Sharawy, Sameer Mirza, Graham R Ball, Andrew R Green, Emad A Rakha: Upregulation of Cyclin B2 (CCNB2) in breast cancer contributes to the development of lymphovascular invasion. Am J Cancer Res 2022;12(2):469-489. (Full text, PDF)
Masanori Oshi, Joy Sarkar, Rongrong Wu, Yoshihisa Tokumaru, Li Yan, Kazuya Nakagawa, Atsushi Ishibe, Ryusei Matsuyama, Itaru Endo, Kazuaki Takabe: Intratumoral density of regulatory T cells is a predictor of host immune response and chemotherapy response in colorectal cancer. Am J Cancer Res 2022;12(2):490-503. (Full text, PDF)
Rongrong Wu, Joy Sarkar, Yoshihisa Tokumaru, Yamato Takabe, Masanori Oshi, Mariko Asaoka, Li Yan, Takashi Ishikawa, Kazuaki Takabe: Intratumoral lymphatic endothelial cell infiltration reflecting lymphangiogenesis is counterbalanced by immune responses and better cancer biology in the breast cancer tumor microenvironment. Am J Cancer Res 2022;12(2):504-520. (Full text, PDF)
Katherine Tucker, Yajie Yin, Stuart-Allison Staley, Ziyi Zhao, Ziwei Fang, Yali Fan, Xin Zhang, Hongyan Suo, Wenchuan Sun, Varun Vijay Prabhu, Joshua E Allen, Chunxiao Zhou, Victoria L Bae-Jump: ONC206 has anti-tumorigenic effects in human ovarian cancer cells and in a transgenic mouse model of high-grade serous ovarian cancer. Am J Cancer Res 2022;12(2):521-536. (Full text, PDF)
An Hu, Jian-Wei Zhang, Li-Yun Yang, Pei-Pei Qiao, Dan Lu: AHRR contributes to inflammatory lymphangiogenesis by activating the EPAS1/VEGFD signaling axis in head and neck cancer. Am J Cancer Res 2022;12(2):537-548. (Full text, PDF)
Piaopiao Xu, Xiangling Chen, Yongping Xu, Li Fu, Yun Li, Haoyu Fu, Qing Yao, Haitian Quan, Liguang Lou: Trastuzumab in combination with PEGylated interferon-α1b exerts synergistic antitumor activity through enhanced inhibition of HER2 downstream signaling and antibody-dependent cellular cytotoxicity. Am J Cancer Res 2022;12(2):549-561. (Full text, PDF)
Akira Fujimori, Hirokazu Hirakawa, Cuihua Liu, Taishin Akiyama, Bevin P Engelward, Jac A Nickoloff, Masao Suzuki, Bing Wang, Mitsuru Nenoi, Sei Sai: Recombinant cell-detecting RaDR-GFP in mice reveals an association between genomic instability and radiation-induced-thymic lymphoma. Am J Cancer Res 2022;12(2):562-573. (Full text, PDF)
Chanjuan Qu, Jian Wang, Yuqing Wang, Fangfei He, Xudong Shi, Zhuoli Zhang, Yining Wang: Multimodality imaging in the assessment of bone marrow-derived mesenchymal stem cell therapy for doxorubicin-induced cardiomyopathy. Am J Cancer Res 2022;12(2):574-584. (Full text, PDF)
Eirini G Martinou, Carla S Moller-Levet, Angeliki M Angelidi: PBX4 functions as a potential novel oncopromoter in colorectal cancer: a comprehensive analysis of the PBX gene family. Am J Cancer Res 2022;12(2):585-600. (Full text, PDF)
Ming-Tsung Lin, Sherry Yueh-Hsia Chiu, Kuo-Chin Chang, Wei-Feng Li, Chee-Chien Yong, Yueh-Wei Liu, Jing-Houng Wang, Fang-Ying Kuo, Chao-Cheng Huang, Chih-Chi Wang, Chang-Chun Hsiao, Tsung-Hui Hu: Significant association between serum Wisteria floribunda agglutinin-positive Mac-2-binding protein and prognosis of hepatocellular carcinoma after surgical treatment. Am J Cancer Res 2022;12(2):601-614. (Full text, PDF, Supplementary Material)
Yun-Ju Ma, Hai-Ping Dai, Qing-Ya Cui, Wei Cui, Wen-Juan Zhu, Chang-Ju Qu, Li-Qing Kang, Ming-Qing Zhu, Xia-Ming Zhu, Dan-Dan Liu, Yu-Feng Feng, Hong-Jie Shen, Tian-Hui Liu, Hui-Ying Qiu, Lei Yu, De-Pei Wu, Xiao-Wen Tang: Successful application of PD-1 knockdown CLL-1 CAR-T therapy in two AML patients with post-transplant relapse and failure of anti-CD38 CAR-T cell treatment. Am J Cancer Res 2022;12(2):615-621. (Full text, PDF)
Nadia N Khan, Tennille Lewin, Amy Hatton, Charles Pilgrim, Liane Ioannou, Luc te Marvelde, John Zalcberg, Sue Evans: Systematic review of the predictors of health service use in pancreatic cancer. Am J Cancer Res 2022;12(2):622-650. (Full text, PDF)
Alessia Fabbri, Laura Bracci: Immunomodulatory properties of CNF1 toxin from E. coli: implications for colorectal carcinogenesis. Am J Cancer Res 2022;12(2):651-660. (Full text, PDF)
Jéssica Vieira de Assis, Lucélia Antunes Coutinho, Ifeoluwa Temitayo Oyeyemi, Oyetunde Timothy Oyeyemi, Rafaella Fortini e Queiroz Grenfell: Diagnostic and therapeutic biomarkers in colorectal cancer: a review. Am J Cancer Res 2022;12(2):661-680. (Full text, PDF)
Jianhang Zhao, Zhaoxu Xu, Yan Liu, Xiaobin Wang, Xinli Liu, Yanan Gao, Ying Jin: The expression of cancer-testis antigen in ovarian cancer and the development of immunotherapy. Am J Cancer Res 2022;12(2):681-694. (Full text, PDF)
Bo Xue, Wen-Min Guo, Jie-Dong Jia, Gaohaer Kadeerhan, Hua-Ping Liu, Tao Bai, Yuan Shao, Dong-Wen Wang: MUC20 as a novel prognostic biomarker in ccRCC correlating with tumor immune microenvironment modulation. Am J Cancer Res 2022;12(2):695-712. (Full text, PDF)
Yu-Hsuan Hung, Ming-Derg Lai, Wen-Chun Hung, Li-Tzong Chen: Semaphorin 4C promotes motility and immunosuppressive activity of cancer cells via CRMP3 and PD-L1. Am J Cancer Res 2022;12(2):713-728. (Full text, PDF)
Nicholas R Liguori, Ashley Sanchez Sevilla Uruchurtu, Leiqing Zhang, Abbas E Abbas, Young S Lee, Lanlan Zhou, Christopher G Azzoli, Wafik S El-Deiry: Preclinical studies with ONC201/TIC10 and lurbinectedin as a novel combination therapy in small cell lung cancer (SCLC). Am J Cancer Res 2022;12(2):729-743. (Full text, PDF)
Rongrong Wu, Masanori Oshi, Mariko Asaoka, Michelle R Huyser, Yoshihisa Tokumaru, Akimitsu Yamada, Li Yan, Itaru Endo, Takashi Ishikawa, Kazuaki Takabe: APOBEC3F expression in triple-negative breast cancer is associated with tumor microenvironment infiltration and activation of cancer immunity and improved survival. Am J Cancer Res 2022;12(2):744-762. (Full text, PDF)
Kyungjoo Cho, Nam Hee Kim, Sang Hyun Seo, Sang Hyun Song, Chul Hee Jeong, Hyun Sil Kim, Jo Eun Um, Minhee Ku, Jaemoon Yang, Jun Yong Park, Sang Hoon Ahn, Jong In Yook, Seung Up Kim: A micellized bone morphogenetic protein-7 prodrug ameliorates liver fibrosis by suppressing transforming growth factor-β signaling. Am J Cancer Res 2022;12(2):763-778. (Full text, PDF)
Chaoyuan Liu, Luxi Qian, Karin A Vallega, Guangzhi Ma, Dan Zong, Luxiao Chen, Shaomeng Wang, Suresh R Ramalingam, Zhaohui Qin, Shi-Yong Sun: The novel BET degrader, QCA570, is highly active against the growth of human NSCLC cells and synergizes with osimertinib in suppressing osimertinib-resistant EGFR-mutant NSCLC cells. Am J Cancer Res 2022;12(2):779-792. (Full text, PDF)
Eriko Katsuta, Abhisha Sawant Dessai, John ML Ebos, Li Yan, Toru Ouchi, Kazuaki Takabe: H2AX mRNA expression reflects DNA repair, cell proliferation, metastasis, and worse survival in breast cancer. Am J Cancer Res 2022;12(2):793-804. (Full text, PDF)
Ziran Bi, Wen Li, Jie Zhao, Lulian Pang, Yanyan Jing, Xiuqing Zhang, Senbang Yao, Xiangxiang Yin, He Zuo, Huaidong Cheng: Negative correlations of psychological distress with quality of life and immunotherapy efficacy in patients with advanced NSCLC. Am J Cancer Res 2022;12(2):805-815. (Full text, PDF)
Yue-Feng Sun, Yuan Wang, Xiao-Dong Li, Hong Wang: SNHG15, a p53-regulated lncRNA, suppresses cisplatin-induced apoptosis and ROS accumulation through the miR-335-3p/ZNF32 axis. Am J Cancer Res 2022;12(2):816-828. (Full text, PDF, Supplementary Table 1)
Ke-Xun Yu, Wei-Jie Yuan, Chang-Hao Huang, Lei Xiao, Run-Sha Xiao, Peng-Wei Zeng, Lu Chen, Zi-Hua Chen: Socioeconomic deprivation and survival outcomes in patients with colorectal cancer. Am J Cancer Res 2022;12(2):829-838. (Full text, PDF)
Ingrid Espinoza, Chandra Kurapaty, Cheol-Hong Park, Travis Vander Steen, Celina G Kleer, Elizabeth Wiley, Alfred Rademaker, Elisabet Cuyàs, Sara Verdura, Maria Buxó, Carol Reynolds, Javier A Menendez, Ruth Lupu: Depletion of CCN1/CYR61 reduces triple-negative/basal-like breast cancer aggressiveness. Am J Cancer Res 2022;12(2):839-851. (Full text, PDF)
Chia-Wen Tsai, Wen-Shin Chang, Yifan Xu, Maosheng Huang, Pheroze Tamboli, Christopher G Wood, Da-Tian Bau, Jian Gu: Prognostic significance of circulating insulin growth-like factor 1 and insulin growth-like factor binding protein 3 in renal cell carcinoma patients. Am J Cancer Res 2022;12(2):852-860. (Full text, PDF)
Xinyao Chang, Xingchen Liu, Haoze Wang, Xuan Yang, Yan Gu: Glycolysis in the progression of pancreatic cancer. Am J Cancer Res 2022;12(2):861-872. (Full text, PDF)
Po-Yuan Huang, I-An Shih, Ying-Chih Liao, Huey-Ling You, Ming-Jen Lee: A novel HDAC11 inhibitor potentiates the tumoricidal effects of cordycepin against malignant peripheral nerve sheath tumor through the Hippo signaling pathway. Am J Cancer Res 2022;12(2):873-892. (Full text, PDF)
Min Tao, Xiaoyu Li, Lei He, Xiaoming Rong, Hongxuan Wang, Jingrui Pan, Zijing Lu, Xiaoni Zhang, Ying Peng: Decreased RNA m6A methylation enhances the process of the epithelial mesenchymal transition and vasculogenic mimicry in glioblastoma. Am J Cancer Res 2022;12(2):893-906. (Full text, PDF, Supplementary Material)
Changxian Li, Hongwei Wang, Ruixiang Chen, Hui Zhang, Yonghua Xu, Bin Zhang, Yong Li, Changhe Zhang, Yue Yang, Xuehao Wang, Xiangcheng Li: Outcomes and recurrence patterns following curative hepatectomy for hepatocellular carcinoma patients with different China liver cancer staging. Am J Cancer Res 2022;12(2):907-921. (Full text, PDF)
Xiao-Yu Liu, Zhi-Jian Liu, Hong He, Chen Zhang, Yun-Long Wang: MicroRNA-101-3p suppresses cell proliferation, invasion and enhances chemotherapeutic sensitivity in salivary gland adenoid cystic carcinoma by targeting Pim-1: Am J Cancer Res. 2015; 5(10): 3015-3029. Am J Cancer Res 2022;12(2):922-923. (Full text, PDF)
Erjie Xia, Yanyan Shen, Adheesh Bhandari, Xiaofen Zhou, Yinghao Wang, Fan Yang, Ouchen Wang: Long non-coding RNA LINC00673 promotes breast cancer proliferation and metastasis through regulating B7-H6 and epithelial-mesenchymal transition: Am J Cancer Res. 2018; 8(7): 1273-1287. Am J Cancer Res 2022;12(2):924-926. (Full text, PDF)
