Shuai Zhao, Wafik S El-Deiry: Non-canonical approaches to targeting hypoxic tumors. Am J Cancer Res 2022;12(12):5351-5374. (Full text, PDF)
Zhongbo Zhu, Lijuan Shi, Yawei Dong, Yanmei Zhang, Fan Yang, Jingjing Wei, Minfeng Huo, Peiqing Li, Xiping Liu: Effect of crosstalk among conspirators in tumor microenvironment on niche metastasis of gastric cancer. Am J Cancer Res 2022;12(12):5375-5402. (Full text, PDF)
Matthew GK Benesch, Rongrong Wu, Gopal Menon, Kazuaki Takabe: High beta integrin expression is differentially associated with worsened pancreatic ductal adenocarcinoma outcomes. Am J Cancer Res 2022;12(12):5403-5424. (Full text, PDF, Supplemental Table 1)
Senbang Yao, Chen Gan, Tao Wang, Qianqian Zhang, Mingjun Zhang, Huaidong Cheng: High ALDH2 expression is associated with better prognosis in patients with gastric cancer. Am J Cancer Res 2022;12(12):5425-5439. (Full text, PDF)
Chunzhen Li, Yijie Tao, Yining Chen, Yunyang Wu, Yixian He, Shulei Yin, Sheng Xu, Yizhi Yu: Development of a metabolism-related signature for predicting prognosis, immune infiltration and immunotherapy response in breast cancer. Am J Cancer Res 2022;12(12):5440-5461. (Full text, PDF)
Ru-Tsun Mai, Chi-Hong Chao, Yao-Wen Chang, Yu-Ching Kao, Yi Cheng, Hsiang-Yu Hsu, Yi-Yuan Su, Chen-Yun Wang, Bo-Ying Lai: Sumoylation participates in the regulation of YB-1-mediated mismatch repair deficiency and alkylator tolerance. Am J Cancer Res 2022;12(12):5462-5483. (Full text, PDF)
Li-Ying Cao, Jia-Yun Xu, Xiao-Tao Zhuo, Wei Zhang, Li-Jia Wei, Jian-Hong Dong, Ren-Ren Bai, Xin Wang, Yuan-Yuan Jiang, Yong-Jie Wang, Xiang-Yang Ye, Tian Xie, Zhi-Hui Huang: 2,2’-((1R,3R,4S)-4-methyl-4-vinylcyclohexane-1,3-diyl) bis(prop-2-en-1-amine), a bisamino derivative of β-Elemene, inhibits glioblastoma growth through downregulation of YAP signaling. Am J Cancer Res 2022;12(12):5484-5499. (Full text, PDF)
Fangyan Jing, Guanglong Liu, Renyi Zhang, Weisong Xue, Jiabao Lin, Huacong Zhu, Yu Zhu, Chaosong Wu, Yang Luo, Tao Chen, Shenglong Li, Ming Bao: PYY modulates the tumorigenesis and progression of colorectal cancer unveiled by proteomics. Am J Cancer Res 2022;12(12):5500-5515. (Full text, PDF)
Sujing Shi, Dewei Xu, Shuchen Gu, Ningyi Xu, Pinglong Xu, Jin Cao, Xin-Hua Feng: Protein tyrosine phosphatase PTPN2 regulates TGF-β signaling through Smad4 dephosphorylation. Am J Cancer Res 2022;12(12):5516-5531. (Full text, PDF)
Dong Min Lim, Junho Kang, Soo-Yeon Woo, Hee-Sun Choi, Munju Kwon, Jayoung Kim, Hae Ryoun Park, Keehoon Jung, Ninib Baryawno, Hyung-Sik Kim, Dongjun Lee, Yun Hak Kim: Risk stratification of patients with right-sided colorectal cancer based on the tumor-infiltrating M1 macrophage. Am J Cancer Res 2022;12(12):5532-5551. (Full text, PDF, Supplementary Table 1)
Jingxiu Xu, Mingjie Chen, Mingyu Hu, Hanlu Wang, Zhongqiang Zuo, Jianguo Wang, Zhiyin Xie: Claudin 19 inhibits the malignant potential of breast cancer cells by modulating extracellular matrix-associated UBE2C/Wnt signaling. Am J Cancer Res 2022;12(12):5552-5563. (Full text, PDF)
Shana Gregory, Yanan Xu, Ping Xie, Jie Fan, Beixue Gao, Nikita Mani, Radhika Iyer, Amy Tang, Juncheng Wei, Shuvam Mohan Chaudhuri, Shengnan Wang, Huiping Liu, Bin Zhang, Deyu Fang: The ubiquitin-specific peptidase 22 is a deubiquitinase of CD73 in breast cancer cells. Am J Cancer Res 2022;12(12):5564-5575. (Full text, PDF)
Po-Yao Hsu, Po-Cheng Liang, Wen-Tsan Chang, Ming-Ying Lu, Wen-Hsuan Wang, Shih-Chang Chuang, Yu-Ju Wei, Tyng-Yuan Jang, Ming-Lun Yeh, Ching-I Huang, Yi-Hung Lin, Chih-Wen Wang, Ming-Yen Hsieh, Nai-Jen Hou, Meng-Hsuan Hsieh, Yi-Shan Tsai, Yu-Min Ko, Ching-Chih Lin, Kuan-Yu Chen, Chia-Yen Dai, Zu-Yau Lin, Shinn-Cherng Chen, Wan-Long Chuang, Chung-Feng Huang, Jee-Fu Huang, Ming-Lung Yu: Artificial intelligence based on serum biomarkers predicts the efficacy of lenvatinib for unresectable hepatocellular carcinoma. Am J Cancer Res 2022;12(12):5576-5588. (Full text, PDF)
Hsueh-Han Tsai, Jyh-Cherng Yu, Huan-Ming Hsu, Chi-Hong Chu, Zhi-Jie Hong, An-Chieh Feng, Chun-Yu Fu, Ming-Shen Dai, Guo-Shiou Liao: The impact of frailty on breast cancer outcomes: evidence from analysis of the Nationwide Inpatient Sample, 2005-2018. Am J Cancer Res 2022;12(12):5589-5598. (Full text, PDF)
Wanyuan Cui, Kelly-Anne Phillips, Richard A Anderson, Prudence A Francis, Sherene Loi, Sibylle Loibl, Ann H Partridge, Louise A Keogh: Selection of endpoints in breast cancer clinical trials: a qualitative study of key trial stakeholders. Am J Cancer Res 2022;12(12):5599-5612. (Full text, PDF)
Ming-Min Chang, Han-Yu Weng, Meng-Shao Lai, Li-Wen Wang, Shang-Hsun Yang, Chia-Ching Wu, Chia-Yih Wang, Bu-Miin Huang: FGF9 promotes cell proliferation and tumorigenesis in TM3 mouse Leydig progenitor cells. Am J Cancer Res 2022;12(12):5613-5630. (Full text, PDF)
Seongdo Jeong, Dongjun Lee, Hae Ryoun Park, Junho Kang, Yeuni Yu, Jae Joon Hwang, Yun Hak Kim: DeepCIA: a novel deep-learning model for cancer type identification using class activation map via transcription factor expression. Am J Cancer Res 2022;12(12):5631-5645. (Full text, PDF, Supplementary Tables 5, 6, 7)
Na Guo, Jiawen Zhang: Interleukin-17 promotes the development of ovarian cancer through upregulation of MTA1 expression. Am J Cancer Res 2022;12(12):5646-5656. (Full text, PDF)
Sei Sai, Taiju Yamada, Keiko Ito, Nobuyuki Kanematsu, Masao Suzuki, Mitsuhiro Hayashi, Masashi Koto: Carbon-ion beam irradiation in combination with cisplatin effectively suppresses xenografted malignant pleural mesothelioma. Am J Cancer Res 2022;12(12):5657-5667. (Full text, PDF)
Adam E Frampton, Jennifer Morton, Owen Sansom, Thomas R Jeffry Evans, Fraser Duthie, Colin J McKay, Jas Samra, Anthony J Gill, Andrew Biankin, Karin A Oien: Prognostic implications of microRNA-21 overexpression in pancreatic ductal adenocarcinoma: an international multicenter study of 686 patients. Am J Cancer Res 2022;12(12):5668-5683. (Full text, PDF)
Wenyun Xu, Li Tan, Sheng Xu, Yongchu Hu, Zui Zou: Application of “twelve-step” approach based on SEEKflex for difficult awake tracheal intubation in patients with cervical spinal tumor. Am J Cancer Res 2022;12(12):5684-5691. (Full text, PDF)
Xiaowei Wu, Yu Deng, Yukun Zu, Jin Yin: Histone demethylase KDM4C activates HIF1α/VEGFA signaling through the costimulatory factor STAT3 in NSCLC: Am J Cancer Res. 2020; 10(2): 491-506. Am J Cancer Res 2022;12(12):5692-5693. (Full text, PDF)
Jianjun Sha, Lei Xia, Qing Han, Chenfei Chi, Yinjie Zhu, Jiahua Pan, Yiran Huang, Weiliang Xia, Baijun Dong, Wei Xue, Chen Yang: Downregulation of circ-TRPS1 suppressed prostatic cancer prognoses by regulating miR-124-3p/EZH2 axis-mediated stemness: Am J Cancer Res. 2020; 10(12): 4372-4385. Am J Cancer Res 2022;12(12):5694-5695. (Full text, PDF)
Weidong Wu, Nanding Yu, Feng Li, Pengqiang Gao, Shiyu Lin, Yong Zhu: RPL35 promotes neuroblastoma progression via the enhanced aerobic glycolysis: Am J Cancer Res. 2021; 11(11): 5701-5714. Am J Cancer Res 2022;12(12):5696. (Full text, PDF)
